Results 41 to 50 of about 4,500,543 (306)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

A Comprehensive Review of AIM2 in Cancer: Functional Roles, Molecular Pathways, and Clinical Relevance

Journal of Immunology Research
Inflammation has been recognized as a component of cancer progression, and inflammasome receptor components also regulate various biological processes, including cell proliferation, gene transcription, and tumorigenesis.
Nuo Wang, Shaoxian Wu, Zhang Fang, Lujun Chen, Xiao Zheng   +4 more
doaj   +1 more source

Chemical and spectroscopic analysis of olive mill waste water during a biological treatment [PDF]

, 2007
The treatment of olive mill waste water was studied on the laboratory scale. Physico–chemical analyses showed the final products had a mean pH of 5.4 without neutralisation and 5.7 when lime was added to the process.
Bailly, Jean-René, El Hajjouji, Houda, Hafidi, Mohamed, Merlina, Georges, Revel, Jean-Claude, Winterton, Peter   +5 more
core   +5 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

IL-1R2 promotes tumorigenesis and modulates the tumor immune microenvironment in colorectal cancer

Cancer Immunology, Immunotherapy
Colorectal cancer (CRC) continues to be a major global health challenge due to its high incidence and mortality rates, emphasizing the critical need for innovative therapeutic strategies. IL-1R2, a member of the IL-1 receptor family, plays a pivotal role
Yanyan Lang, Hao Huang, Hongwei Jiang, Shaoxian Wu, Zhang Fang, Dachuan Zhang, Heya Qian, Yingting Liu, Maoling Yuan, Bin Xu, Lujun Chen, Xiao Zheng, Jingting Jiang   +12 more
doaj   +1 more source

EVALUATION OF DIFFERENT BIOLOGICAL WASTE TREATMENT STRATEGIES [PDF]

, 2002
Biological treatment of organic waste by aerobic composting and anaerobic digestion (biogas production) was compared with respect to a number of environmental effects and sustainability criterias including energy balance, nutrient recycling, global ...
Møller, J., Reeh, U.
core  

Protein folding disorders: Toward a basic biological paradigm [PDF]

, 2010
Mechanistic 'physics' models of protein folding fail to account for the observed spectrum of protein folding and aggregation disorders, suggesting that a more appropriately biological paradigm will be needed for understanding the etiology ...
Rodrick Wallace
core   +3 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

IL-1β-mediated suppression of CIITA attenuates IFN-γ-induced MHC-II expression on Fibroblasts

Cell Communication and Signaling
Background Cancer-associated fibroblasts (CAFs) are key regulators in tumor microenvironment and tumor immunity, partly through MHC-II expression that modulates T-cell differentiation.
Lujun Chen, Hongwei Jiang, Bo Tan, Renhao Geng, Junjun Chen, Shaoxian Wu, Zhang Fang, Yanyan Lang, Hui Ma, Xiao Zheng, Jingting Jiang   +10 more
doaj   +1 more source

Radiotherapy Upregulates Programmed Death Ligand-1 through the Pathways Downstream of Epidermal Growth Factor Receptor in Glioma

EBioMedicine, 2018
Background: In the present study, we aimed to investigate the role of epidermal growth factor receptor (EGFR) pathway in the up-regulation of programmed death ligand-1 (PD-L1) caused by radiotherapy (RT).
Xing Song, Yingjie Shao, Tianwei Jiang, Yun Ding, Bin Xu, Xiao Zheng, Qi Wang, Xin Chen, Wendong Gu, Changping Wu, Jingting Jiang   +10 more
doaj   +1 more source