Results 51 to 60 of about 27,882,966 (366)
BMC CancerCD8+T cells secreting granzyme A (GZMA) can induce pyroptosis in tumor cells by effectively cleaving gasdermin B (GSDMB), which is stimulated by interferon-γ (IFN-γ). However, the interaction between GZMA-expressing CD8+T cells and GSDMB-expressing tumor
Jiayi Yang +11 more
doaj +1 more source
Immune Regulation and Antitumor Effect of TIM-1
Journal of Immunology Research, 2016 T cells play an important role in antitumor immunity, and the T cell immunoglobulin domain and the mucin domain protein-1 (TIM-1) on its surface, as a costimulatory molecule, has a strong regulatory effect on T cells.
Peng Du +3 more
doaj +1 more source
Cancer Cell International, 2018 Following publication of the original article [1], the authors reported a typing mistake in the title. In this Correction the incorrect and correct titles are shown.
Lujun Chen +6 more
doaj +1 more source
Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari +5 more
wiley +1 more source
Expression of B7-H6 expression in human hepatocellular carcinoma and its clinical significance
Cancer Cell International, 2018 Background Recent studies have suggested that B7-H6, a new member of the B7 family of ligands, not only is a crucial regulator of NK cell-mediated immune responses but also has important clinical implications due to its abnormal expression in many human ...
Lujun Chen +6 more
doaj +1 more source
Capsule endoscopy in Crohn's disease surveillance: A monocentric, retrospective analysis in Italy
Frontiers in Medical Technology, 2022 BackgroundCrohn's disease (CD) is a potentially debilitating condition that burdens Italian healthcare substantially. The symptomatic management relies on prompt therapy adjustment to reduce flares and follow-up diagnostic inputs to maximise remission ...
Carlo Calabrese +10 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
Biologic agents in the treatment of glomerulonephritides [PDF]
Nephrology, 2015 AbstractCurrent immunosuppression strategies in the treatment of glomerulonephritides remain unsatisfactory, especially in glomerular diseases that are frequently relapsing or are resistant to treatment. Toxicities associated with the use of drugs with non‐specific targets for the immune response result in treatment non‐compliance, and increase ...
See Cheng, Yeo, Adrian, Liew
openaire +2 more sources
Use of Biological Treatments in Elderly Patients with Skin Psoriasis in the Real World
Life, 2021 Biological drugs have prompted a revolution in the treatment of patients with psoriasis because of their favourable efficacy/risk profile. The aims of our study are to determine whether there is any difference in the pattern of use of biological ...
Cristina Galache Osuna +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source