Results 61 to 70 of about 4,500,543 (306)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash +4 more
wiley +1 more source
Expression of B7-H6 expression in human hepatocellular carcinoma and its clinical significance
Cancer Cell International, 2018 Background Recent studies have suggested that B7-H6, a new member of the B7 family of ligands, not only is a crucial regulator of NK cell-mediated immune responses but also has important clinical implications due to its abnormal expression in many human ...
Lujun Chen +6 more
doaj +1 more source
Early Condylectomy: Biological Considerations [PDF]
, 2018 Objective: To describe the early treatment of two patients with unilateral condylar hyperplasia (UCH) diagnosis and therapeutic surgical protocol (early condylectomy) supported by the current biological knowledge about the development and repair of ...
Almeida, Luis Eduardo +2 more
core +1 more source
Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report
Pediatric Blood &Cancer, EarlyView.ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan +6 more
wiley +1 more source
Mechanism of T cell regulation by microRNAs
Cancer Biology & Medicine, 2013 MicroRNAs (miRNAs) are small, non-coding single-stranded RNAs that can modulate target gene expression at posttranscriptional level and participate in cell proliferation, differentiation, and apoptosis. T cells have important functions in acquired immune
Juan Liu +3 more
doaj +1 more source
The Performance of Net-Like Rotating Biological Contactor Bioreactor in Removal of Sulfamethoxazole Antibiotic [PDF]
آب و فاضلاب, 2019 Pharmaceutical wastewater treatment is a complicated process due to presence of various kinds of toxic chemicals and antibiotics that are harmful to any type of organisms.
Nastaran Azimi +2 more
doaj +1 more source
Aberrant fatty acid profile and FFAR4 signaling confer endocrine resistance in breast cancer
Journal of Experimental & Clinical Cancer Research, 2019 Background Evidence suggests that fatty acid receptor FFAR4 plays a tumor-promoting role in adipose tissue-adjacent malignancies, but its clinical relevance remains unexplored.
Xiao Chu +16 more
doaj +1 more source
Off-label use of rituximab in dermatology: pemphigus treatment [PDF]
Anais Brasileiros de Dermatologia, 2013 Since its approval in 1997 by the FDA (United States Food and Drug Administration), rituximab has been used for certain B-cell lymphomas and treatment-resistant rheumatoid arthritis.
Lislaine Bomm +4 more
doaj +1 more source
Psychobiological factors of resilience and depression in late life. [PDF]
, 2019 In contrast to traditional perspectives of resilience as a stable, trait-like characteristic, resilience is now recognized as a multidimentional, dynamic capacity influenced by life-long interactions between internal and environmental resources.
Funes, Cynthia +3 more
core +2 more sources
Biological treatment of psoriatic arthritis [PDF]
Vnitřní lékařství, 2018 Psoriatic arthritis (PsA) is a heterogeneous disease affecting, besides synovial joints, also the entheses, the soft tissues of the whole finger (dactylitis) and the axial skeleton. Currently the classification criteria CASPAR are used to diagnose PsA.
openaire +2 more sources