Results 71 to 80 of about 27,882,966 (366)

Revolutionizing tumor immunotherapy: unleashing the power of progenitor exhausted T cells

Cancer Biology & Medicine
In exploring persistent infections and malignancies, a distinctive subgroup of CD8+ T cells, progenitor exhausted CD8+ T (Tpex) cells, has been identified.
Zhang Fang, Xinyi Ding, Hao Huang, Hongwei Jiang, Jingting Jiang, Xiao Zheng   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Targeting lymphotoxin β receptor: from mechanism to precision therapy

Journal of Enzyme Inhibition and Medicinal Chemistry
The tumour necrosis factor receptor superfamily (TNFRSF) represents a pivotal signalling network that orchestrates immune homeostasis and regulates cell fate decisions.
Panpan Zheng, Jingyi Dai, Xiao Zheng, Jingting Jiang   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

NAALADL2-AS2 functions as a competing endogenous RNA to regulate apoptosis and drug resistance in DLBCL

Cancer Biology & Therapy
To explore role of NAALADL2-AS2 as ceRNA in DLBCL. Fluorescence in situ hybridization was used to determine location of NAALADL2-AS2 in cells and to verify its expression in DLBCL tissues.
Xiaoli Xu, Juan Liu, Cheng Fang, Xu Deng, Danxia Zhu, Jingting Jiang, Changping Wu   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Critical review on biological treatment strategies of dairy wastewater

Desalination and Water Treatment, 2019
Dairy products are one of the richest sources of vital nutrients in the diet of human beings and it occupies an important place in satisfying their nutrient requirements.
G. J. Joshiba, P. Kumar, Carolin C. Femina, E. Jayashree, R. Racchana, S. Sivanesan   +5 more
semanticscholar   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

From traditional adsorption processes to bioremediation: Modern technologies for purifying natural waters from pollutants [PDF]

Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология
The relevance of the study is determined by the fact that human activity has led to an increase in the anthropogenic impact on the environment. Various pollutants from a large number of discharges of municipal, industrial and medical wastewater are ...
Salishcheva, Olesya Vladimirovna, Ворошилин, Роман Алексеевич   +1 more
doaj   +1 more source