Results 211 to 220 of about 739,943 (342)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

900 TBio BFX 4101: a neoantigen prioritization pipeline for selected tumor-infiltrating lymphocyte therapy

Journal for ImmunoTherapy of Cancer, 2023
Quanyuan He, Christian E Laing, Stewart E Abbot, Tony Collins, Meghan Verschoor, Chantal G Martin, Michael Ciancanelli   +6 more
doaj   +1 more source

Trends in Psoriatic Arthritis Management From 1993 to 2019: Rise of Biologics and Decline of Oral Small Molecules. [PDF]

J Psoriasis Psoriatic Arthritis
Woodie BR, Balachandar S, Fleischer AB.
europepmc   +1 more source

THE EFFECTS OF RADIATIONS ON BIOLOGICAL SYSTEMS [PDF]

, 1935
Raymond G. Hussey, William R. Thompson
openalex   +1 more source

Biological diversity [PDF]

Current Biology, 2005
openaire   +2 more sources

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Essays upon heredity and kindred biological problems

, 1889
Auǵust Weismann, Edward Bagnall Poulton, S. Schönland, A. E. Shipley   +3 more
openalex   +2 more sources

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

Molecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

Clinical remission in chronic rhinosinusitis with nasal polyps with biologics: a premature promise? [PDF]

Eur Respir Rev
Gelardi M, Giancaspro R.
europepmc   +1 more source

The distribution of bird-life in Colombia; a contribution to a biological survey of South America

, 1917
Frank M. Chapman, Louis Agassiz Fuertes
openalex   +2 more sources