Results 271 to 280 of about 739,943 (342)

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Biologics for the Treatment of Moderate-to-Severe Plaque Psoriasis: A Systematic Review and Network Meta-analysis. [PDF]

Dermatol Ther (Heidelb)
Lebwohl MG, Carvalho A, Asahina A, Zhang J, Fazeli MS, Kasireddy E, Serafini P, Ferro T, Gogineni R, Thaçi D.   +9 more
europepmc   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

FEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Follow-On Biologics, Patient Safety and Policy Focus of JSPH Program in DC [PDF]

, 2009

core   +1 more source

Resolution of Superimposed Linear Psoriasis With Bimekizumab After Resistance to Several Biologics. [PDF]

Cureus
Yatsuzuka K, Muto J, Yoshida S, Shiraishi K, Fujisawa Y.   +4 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Use of Biologics During Pregnancy Among Patients With Autoimmune Conditions.

JAMA Netw Open
Ewig CLY, Wang Y, Smolinski NE, Thai TN, Rasmussen SA, Winterstein AG.   +5 more
europepmc   +1 more source

Real-world evidence on biologic use in paediatric asthma: there but not there yet? [PDF]

ERJ Open Res
Chen W.
europepmc   +1 more source