Results 271 to 280 of about 774,999 (361)

Biologic Drug Prices in Medicare Part B After Entry of Biosimilars to the Market.

JAMA Netw Open
Abdelaziz A, Winn AN, Dusetzina SB, Mitchell AP.   +3 more
europepmc   +1 more source

The unintended consequences of the inflation reduction act on biosimilar market incentives and Medicare savings. [PDF]

Health Aff Sch
Beinfeld MT, Ghule P, LaMountain F, Wong W, Ko S, Chambers JD.   +5 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Impact of clinical factors and season on inflammatory cytokines in biologic-treated and untreated asthma. [PDF]

Respir Res
Nopsopon T, Cabrera-Perez J, Lee PY, Brodeur KE, Lugogo NL, Hsu EE, LeSon C, Hahn G, Carr SA, Weiss ST, Akenroye A.   +10 more
europepmc   +1 more source

Biological Control of the Grasshopper Hesperotettix viridis pratensis by the Nematode Mermis nigrescens.

, 1971
S. Mongkolkiti, Robert M. Hosford
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Global prevalence of eligibility for biologic therapy in ATS/ERS-defined severe asthma: A systematic review. [PDF]

World Allergy Organ J
Yang F, Salciccioli JD, Patel RE, McClean M, Bloom CI.   +4 more
europepmc   +1 more source

Calcium and phosphate and their role in matrix vesicles: A biological view

Larwsk Hayann, Pietro Ciancaglini, Ana Paula Ramos, Dobrawa Napierala   +3 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source