Results 81 to 90 of about 481,378 (312)

Education in Computational Biology Today and Tomorrow

PLoS Computational Biology, 2013
The etymology of the word “education” in Wikipedia is enlightening: “a rearing” and “I lead forth” (http://en.wikipedia.org/wiki/Education#Etymology). Computational biology educators are leading and raising the next generation of scientists and, in doing so, are in need of new tools, methods, and approaches.
Joanne A. Fox, B. F. Francis Ouellette
openaire   +4 more sources

Be aware of behaviour: learning and teaching behavioural biology in secondary education

, 2012
Learning and teaching New Biology requires new educational approaches to acquire knowledge of the (new) biology, competences to understand complex systems, and new learning and teaching strategies.
van Moolenbroek, J., Biology Education, Sub Onderwijsinstituut Biologie   +2 more
core  

Expertise for teaching biology situated in the context of genetic testing

, 2012
\u3cp\u3eContemporary genomics research will impact the daily practice of biology teachers who want to teach up-to-date genetics in secondary education.
Vermunt, J. D., Sub Mathematics Education, Biology Education, Akkerman, S.F., van der Zande, P.A.M., Brekelmans, JMG Mieke, Teacher learning and expertise throughout the professional career, Akkerman, Sanne F, Brekelmans, M., Freudenthal Institute for Science and Mathematics Education, Vermunt, JD, Sub Onderwijsinstituut Biologie, Interactivity and learning in education, Afd Educatie, Zande, Paul Van der, Waarlo, Arend Jan, Waarlo, A.J.   +16 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Evaluating Universal Design for Learning and Active Learning Strategies in Biology Open Educational Resources (OERs)

Teaching & Learning Inquiry: The ISSOTL Journal
With the onset of COVID-19, colleges and universities moved to emergency remote teaching, and instructors immediately adjusted their curricula. Many instructors adapted or developed new online lessons that they subsequently published as Open Educational
Krista Wojdak, Michelle K. Smith, Hayley Orndorf, Marie Louise Ramirez   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Boosting 21st Century Skills: Project-Based Microteaching’s Impact on Communication and Collaboration in Biology Education

Utamax
This study uniquely addresses the gap in preparing prospective biology teachers for 21st-century education by integrating Project-Based Learning (PjBL) into microteaching.
Ali Sadikin, Muhammad Rusdi, Muhammad Haris Effendi Hasibuan, Jodion Siburian   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source