Results 51 to 60 of about 5,448,839 (367)

Inferring Biologically Relevant Models: Nested Canalyzing Functions [PDF]

open access: yes, 2010
Inferring dynamic biochemical networks is one of the main challenges in systems biology. Given experimental data, the objective is to identify the rules of interaction among the different entities of the network.
Hinkelmann, Franziska   +1 more
core   +3 more sources

Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type in vitro model of the choroid plexus

open access: yesiScience, 2022
Summary: The choroid plexus (CP) is a highly vascularized structure containing endothelial and epithelial cells located in the ventricular system of the central nervous system (CNS).
Walter Muranyi   +9 more
doaj  

AlphaFold and the future of structural biology

open access: yesIUCrJ, 2023
This editorial acknowledges the transformative impact of new machine-learning methods, such as the use of AlphaFold, but also makes the case for the continuing need for experimental structural biology.
Randy J. Read   +4 more
doaj   +1 more source

Critical assessment of methods of protein structure prediction (CASP)—Round XIV

open access: yesProteins: Structure, Function, and Bioinformatics, 2021
Critical assessment of structure prediction (CASP) is a community experiment to advance methods of computing three‐dimensional protein structure from amino acid sequence. Core components are rigorous blind testing of methods and evaluation of the results
A. Kryshtafovych   +4 more
semanticscholar   +1 more source

Critical assessment of methods of protein structure prediction: Progress and new directions in round XI [PDF]

open access: yes, 2016
Modeling of protein structure from amino acid sequence now plays a major role in structural biology. Here we report new developments and progress from the CASP11 community experiment, assessing the state of the art in structure modeling. Notable points
Fidelis, Krzysztof   +4 more
core   +1 more source

The proteomic profile of the human myotendinous junction

open access: yesiScience, 2022
Summary: Proteomics analysis of skeletal muscle has recently progressed from whole muscle tissue to single myofibers. Here, we further focus on a specific myofiber domain crucial for force transmission from muscle to tendon, the myotendinous junction ...
Anders Karlsen   +8 more
doaj  

Research methods and data analysis techniques in education articles published by Indonesian biology educational journals

open access: yesJurnal Pendidikan Biologi Indonesia, 2018
The essential of studies which focus on research methods in biology educational field is providing recommendations for the next researchers the proper methods they need to use. Unfortunately, this kind of research is still hard to find in Indonesia.
Ahmad Fauzi, Ika Wahyu Pradipta
semanticscholar   +1 more source

Evolving methods for rational de novo design of functional RNA molecules

open access: yes, 2019
Artificial RNA molecules with novel functionality have many applications in synthetic biology, pharmacy and white biotechnology. The de novo design of such devices using computational methods and prediction tools is a resource-efficient alternative to ...
Findeiß, Sven   +3 more
core   +1 more source

Quantitative biology: where modern biology meets physical sciences [PDF]

open access: yes, 2014
Quantitative methods and approaches have been playing an increasingly important role in cell biology in recent years. They involve making accurate measurements to test a predefined hypothesis in order to compare experimental data with predictions ...
Fai, Thomas G.   +5 more
core   +2 more sources

Three live-imaging techniques for comprehensively understanding the initial trigger for insulin-responsive intracellular GLUT4 trafficking

open access: yesiScience, 2022
Summary: Quantitative features of GLUT4 glucose transporter’s behavior deep inside cells remain largely unknown. Our previous analyses with live-cell imaging of intracellular GLUT4 trafficking demonstrated two crucial early events responsible for ...
Hiroyasu Hatakeyama   +2 more
doaj  

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