Results 231 to 240 of about 105,850 (272)

Bright Ferritin for Non‐Invasive MRI Monitoring of the Fate of Transplanted hPSC‐Cardiomyocytes in the Infarcted Rat Heart

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate that a recently reported bright ferritin magnetic resonance imaging (MRI) platform can track transplanted human pluripotent stem cell (hPSC)‐derived cardiomyocytes (hPSC‐CMs) longitudinally and on‐demand in the rat heart.
Keyu Zhuang, Faisal J. Alibhai, Beiping Qiang, Rocco Romagnuolo, Kyle D. W. Vollett, Bradley K. C. Freeman, M. Juliana Gomez‐Garcia, Tamilla Sadikov Valdman, Tameshwar Ganesh, Yu‐Qing Zhou, Hai‐Ying Mary Cheng, Michael A. Laflamme, Hai‐Ling Margaret Cheng   +12 more
wiley   +1 more source

FDA-approved IMPDH inhibitors synergize with ribavirin to inhibit respiratory syncytial virus by interfering with purine <i>de novo</i> synthesis. [PDF]

Emerg Microbes Infect
Hu H, Wang Q, Ai Q, Zhou P, He Y, Ye Z, Ma K, Zhou M, Huang S, Wang L, Qi N, Xiao G, Wang S.   +12 more
europepmc   +1 more source

Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

Phytotherapy Research, EarlyView.
Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi, Jing‐wei Zhao, Jia‐yun Zhu, Cheng Zhao, Zi‐yi Yang, Li‐jia Pan, Ben Ma, Zheng‐yu Chen, Zi‐ying Wang, Chun‐jie Li, Shi‐lei Liu, Jia‐wei Mei, Ping Dong   +12 more
wiley   +1 more source

Low temperature abolishes human cellular circadian rhythm through Hopf bifurcation. [PDF]

NPJ Syst Biol Appl
Xiao Y, Sainoo Y, Nishimura T, Ito H.
europepmc   +1 more source

Epigallocatechin‐3‐Gallate Suppresses Glioma by Targeting Integrin αvβ3/FAK/ERK Signaling Axis and Matrix Metalloproteinases

Phytotherapy Research, EarlyView.
EGCG suppresses glioma progression by targeting integrin αvβ3/FAK/ERK signaling and inhibiting MMP‐2/MMP‐9‐mediated ECM degradation, thereby blocking proliferation, migration, invasion, and promoting apoptosis. ABSTRACT Epigallocatechin‐3‐gallate (EGCG), the most abundant and biologically active catechin in green tea, has been widely reported to ...
Rui Sun, Yonghan Pan, Ning Yang, Bing Kang, Hong Xiao, Xianglong Tang, Taiping Li, Mengjie Zhao   +7 more
wiley   +1 more source

Temperature changes are signaled in cyanobacteria through the PipX interaction network. [PDF]

Front Microbiol
Llop A, Bibak S, Mata-Balaguer T, Tremiño L, Fuertes-García L, Neira JL, Dixon R, Contreras A.   +7 more
europepmc   +1 more source

Rhyming in the cold: first evidence of soniferous fishes in the Southern Ocean

Remote Sensing in Ecology and Conservation, EarlyView.
The acoustic ecology of Southern Ocean fishes remains unknown due to a lack of dedicated acoustic research on the fishes of this ocean. Passive acoustic monitoring data were collected at the South African sub‐Antarctic Prince Edward Islands using an underwater acoustic recorder, and towed underwater Ski‐Monkey cameras were deployed to identify fish ...
Fannie W. Shabangu, Grant van der Heever, Charles von der Meden, Hannah Truter, Stephen J. Lamberth, Ofer Gon   +5 more
wiley   +1 more source

Applications of bioluminescence-mediated photodynamic therapy (BL-PDT) for the treatment of deep-seated tumours. [PDF]

Discov Oncol
Mohlongo M, George BP, Abrahamse H.
europepmc   +1 more source

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

Small, EarlyView.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran, Yevel Flores‐Garcia, Chanel M. Naar, Shuxiong Chen, Mili Mehta, Fijs W. B. van Leeuwen, Abhai Tripathi, Rajagopal Murugan, Meta Roestenberg, Fidel Zavala, Bernd H. A. Rehm   +10 more
wiley   +1 more source

A luminescence-based point-of-care HIV viral load test for antiretroviral therapy monitoring. [PDF]

Lab Chip
Kim S, Hong HR, Oh JM, Chun J, Chellappaa A, Yoo J, Husain SM, Lee J, Kim J, Thirumalaraju P, Song Y, Kanakasabapathy MK, Gwak J, Hardie JM, Kuritzkes DR, Li JZ, Tsibris AM, Shafiee H.   +17 more
europepmc   +1 more source