Results 131 to 140 of about 44,745 (290)

Bioluminescence imaging of TNBC intracranial tumor model.

, 2013
(A) Dynamic changes in intracranial tumor growth after treatment as measured by bioluminescence imaging in photons/second. Groups are as follows: Control (black), non-liposomal doxorubicin (NonL-doxo, green), PEGylated liposomal doxorubicin [PLD] (blue),
Tal Kafri (220972), Ryan Bash (408851), Charlene Santos (408850), C. Ryan Miller (165511), Charles M. Perou (109977), Norman Sharpless (408853), Allison Schorzman (408849), Carey K. Anders (43869), Allison M. Deal (408847), Barbara Adamo (408845), Lisa Carey (408852), William C. Zamboni (408854), Olga Karginova (408846), Sumit Rawal (408848), David Darr (218674)   +14 more
core   +1 more source

Amplification of Endoplasmic Reticulum Stress via Inhibiting Lipid Droplet Formation to Enhance Chemodynamic Immunotherapy

Advanced Science, EarlyView.
An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai, Shaoru Zhuang, Yang Zhu, Rujiang Ao, Meili Yu, Tingting Cui, Jun Wang, Xuegang Niu, Hongwei Huang, Shanshan Peng, Yu He, Lisen Lin, Huanghao Yang   +12 more
wiley   +1 more source

In vivo dual substrate bioluminescent imaging.

Journal of visualized experiments : JoVE, 2011
Our understanding of how and when breast cancer cells transit from established primary tumors to metastatic sites has increased at an exceptional rate since the advent of in vivo bioluminescent imaging technologies. Indeed, the ability to locate and quantify tumor growth longitudinally in a single cohort of animals to completion of the study as opposed
Wendt, Michael K., Molter, Joseph, Flask, Christopher A., Schiemann, William P.   +3 more
openaire   +2 more sources

Optimizing bioluminescence imaging to study protozoan parasite infections.

, 2014
Bioluminescence imaging is a non-invasive technique which can be used to monitor infections in real-time. However, its utility is restricted by difficulties in detecting pathogens in deep tissue.
Kelly, John M, Taylor, Martin C
core   +1 more source

Asymmetrically Coordinated Dual‐Atom Manganese Contrast Agents Enabling High‐Efficiency T1 Enhanced MRI for Precise Tumor Visualization

Advanced Science, EarlyView.
A novel dual‐atom manganese MRI contrast agent (Mn‐BN) with a unique asymmetric coordination geometry provided a promising platform for sensitive and specific tumor imaging. In mice model, Mn‐BN nanoparticles precisely functioned as both a primary tumor‐specific enhancer in subcutaneous models and a hepatocyte‐specific agent in liver metastases models ...
Ding Yang, Qing‐Yang Li, Jianli Liang, Gengyou Li, Nan Sun, Qianqian Song, Haitao Zhu, Xiaoting Li, Zechuan Li, Jiankai Dong, Weisheng Guo, Yafang Xiao, Chun‐Sing Lee, Ying‐Shi Sun   +13 more
wiley   +1 more source

A dual-luciferase bioluminescence system for the assessment of cellular therapies

Molecular Therapy: Oncology
Bioluminescence imaging is a well-established platform for evaluating engineered cell therapies in preclinical studies. However, despite the discovery of new luciferases and substrates, optimal combinations to simultaneously monitor two cell populations ...
Alejandro G. Torres Chavez, Mary K. McKenna, Kishore Balasubramanian, Lisa Riffle, Nimit L. Patel, Joseph D. Kalen, Brad St. Croix, Ann M. Leen, Pradip Bajgain   +8 more
doaj   +1 more source

In Vivo Bioluminescence Imaging of Transplanted Mesenchymal Stem Cells as a Potential Source for Pancreatic Regeneration

Molecular Imaging, 2014
Stem cell therapy has been studied intensively as a promising therapeutic strategy toward a cure for diabetes. To study the effect of mesenchymal stem cell (MSC) transplantation for pancreatic regeneration, we monitored the localization and distribution ...
Song Lee, Hyewon Youn, Taemoon Chung, Do Won Hwang, So Won Oh, Keon Wook Kang, June-Key Chung, Dong Soo Lee   +7 more
doaj   +1 more source

Bioluminescence imaging and hematoxylin and eosin staining of subcutaneous tissue.

, 2019
A, Time course of graft survival as assessed by bioluminescence imaging. B, Quantification of bioluminescence. C, Hematoxylin and eosin staining of serially sectioned subcutaneous tissues collected at days 1, 7, 10, and 14.
Ai Kawamura (651809), Koichi Toda (651812), Takayuki Asahara (191004), Shigeru Miyagawa (310845), Yuki Nakamura (138324), Akima Harada (3387104), Yoshiki Sawa (219191), Satsuki Fukushima (75828), Takuji Kawamura (651807), Shohei Yoshida (517200), Noriyuki Kashiyama (651808), Haruchika Masuda (219184)   +11 more
core   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

Development of Firefly Luciferase Bioluminescence for In vivo Optical Imaging

, 2018
Firefly luciferase is ubiquitously used as a genetic reporter for the non-invasive bioluminescence imaging of small animal models. This widespread use of Firefly luciferase in vivo has been facilitated by genetic engineering producing mutants which are ...
Stowe, Cassandra
core