Results 11 to 20 of about 64,944 (323)

Qualitative in vivo Bioluminescence Imaging

open access: yesBio-Protocol, 2018
Bioluminescence imaging (BLI) technology is an advanced method of carrying out molecular imaging on live laboratory animals in vivo. This powerful technique is widely-used in studying a variety of biological processes, and it has been an ideal tool in ...
Devbarna Sinha   +2 more
doaj   +5 more sources

Color-tunable bioluminescence imaging portfolio for cell imaging [PDF]

open access: yesScientific Reports, 2021
The present study describes a color-tunable imaging portfolio together with twelve novel coelenterazine (CTZ) analogues. The three groups of CTZ analogues create diverse hues of bioluminescence (BL) ranging from blue to far red with marine luciferases ...
Shota Tamaki   +6 more
doaj   +3 more sources

Multi-Modal Multi-Spectral Intravital Macroscopic Imaging of Signaling Dynamics in Real Time during Tumor–Immune Interactions

open access: yesCells, 2021
A major obstacle in studying the interplay between cancer cells and the immune system has been the examination of proposed biological pathways and cell interactions in a dynamic, physiologically relevant system in vivo.
Tracy W. Liu   +3 more
doaj   +1 more source

Bioluminescence Imaging [PDF]

open access: yesProceedings of the American Thoracic Society, 2005
Bioluminescence refers to the process of visible light emission in living organisms. Bioluminescence imaging is a powerful methodology that has been developed over the last decade as a tool for molecular imaging of small laboratory animals, enabling the study of ongoing biological processes in vivo.
Ruxana T, Sadikot, Timothy S, Blackwell
openaire   +2 more sources

Molecular Design of d-Luciferin-Based Bioluminescence and 1,2-Dioxetane-Based Chemiluminescence Substrates for Altered Output Wavelength and Detecting Various Molecules

open access: yesMolecules, 2021
Optical imaging including fluorescence and luminescence is the most popular method for the in vivo imaging in mice. Luminescence imaging is considered to be superior to fluorescence imaging due to the lack of both autofluorescence and the scattering of ...
Hideo Takakura
doaj   +1 more source

Multi-Modal Multi-Spectral Intravital Microscopic Imaging of Signaling Dynamics in Real-Time during Tumor–Immune Interactions

open access: yesCells, 2021
Intravital microscopic imaging (IVM) allows for the study of interactions between immune cells and tumor cells in a dynamic, physiologically relevant system in vivo. Current IVM strategies primarily use fluorescence imaging; however, with the advances in
Tracy W. Liu   +2 more
doaj   +1 more source

Accepting higher morbidity in exchange for sacrificing fewer animals in studies developing novel infection-control strategies. [PDF]

open access: yes, 2020
Preventing bacterial infections from becoming the leading cause of death by the year 2050 requires the development of novel, infection-control strategies, building heavily on biomaterials science, including nanotechnology.
Busscher, Henk J.   +16 more
core   +2 more sources

Molecular Imaging Using Bioluminescence [PDF]

open access: bronzeThe Open Nuclear Medicine Journal, 2010
Recent progress in the development of non-invasive imaging technologies continues to strengthen the role of molecular imaging in biological research. Small animal imaging with bioluminescence has been validated recently in a variety of research models and have been shown to provide continuous quantitative monitoring of the location(s), magnitude, and ...
Byeong Il Lee, Jung‐Joon Min
openalex   +2 more sources

Smartphone-Based Portable Bioluminescence Imaging System Enabling Observation at Various Scales from Whole Mouse Body to Organelle

open access: yesSensors, 2020
Current smartphones equipped with high-sensitivity and high-resolution sensors in the camera can respond to the needs of low-light imaging, streaming acquisition, targets of various scales, etc.
Mitsuru Hattori   +4 more
doaj   +1 more source

In vivo imaging of Zika virus reveals dynamics of viral invasion in immune-sheltered tissues and vertical propagation during pregnancy [PDF]

open access: yes, 2020
Rationale: Zika virus (ZIKV) is a pathogenic virus known to cause a wide range of congenital abnormalities, including microcephaly, Guillain-Barre syndrome, meningoencephalitis, and other neurological complications, in humans. This study investigated the
Hu, Q   +12 more
core   +1 more source

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