Results 11 to 20 of about 63,349 (279)
Qualitative in vivo Bioluminescence Imaging
Bio-Protocol, 2018 Bioluminescence imaging (BLI) technology is an advanced method of carrying out molecular imaging on live laboratory animals in vivo. This powerful technique is widely-used in studying a variety of biological processes, and it has been an ideal tool in ...
Devbarna Sinha +2 more
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Color-tunable bioluminescence imaging portfolio for cell imaging [PDF]
Scientific Reports, 2021 The present study describes a color-tunable imaging portfolio together with twelve novel coelenterazine (CTZ) analogues. The three groups of CTZ analogues create diverse hues of bioluminescence (BL) ranging from blue to far red with marine luciferases ...
Shota Tamaki +6 more
doaj +3 more sources
Proceedings of the American Thoracic Society, 2005 Bioluminescence refers to the process of visible light emission in living organisms. Bioluminescence imaging is a powerful methodology that has been developed over the last decade as a tool for molecular imaging of small laboratory animals, enabling the study of ongoing biological processes in vivo.
Ruxana T, Sadikot, Timothy S, Blackwell
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Accepting higher morbidity in exchange for sacrificing fewer animals in studies developing novel infection-control strategies. [PDF]
, 2020 Preventing bacterial infections from becoming the leading cause of death by the year 2050 requires the development of novel, infection-control strategies, building heavily on biomaterials science, including nanotechnology.
Busscher, Henk J. +16 more
core +2 more sources
In vivo imaging of Zika virus reveals dynamics of viral invasion in immune-sheltered tissues and vertical propagation during pregnancy [PDF]
, 2020 Rationale: Zika virus (ZIKV) is a pathogenic virus known to cause a wide range of congenital abnormalities, including microcephaly, Guillain-Barre syndrome, meningoencephalitis, and other neurological complications, in humans. This study investigated the
Hu, Q +12 more
core +1 more source
Sensors, 2020 Current smartphones equipped with high-sensitivity and high-resolution sensors in the camera can respond to the needs of low-light imaging, streaming acquisition, targets of various scales, etc.
Mitsuru Hattori +4 more
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Development of bioluminescent bioreporters for in vitro and in vivo tracking of Yersinia pestis. [PDF]
PLoS ONE, 2012 Yersinia pestis causes an acute infection known as the plague. Conventional techniques to enumerate Y. pestis can be labor intensive and do not lend themselves to high throughput assays.
Yanwen Sun +3 more
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Emerging tools for bioluminescence imaging
Current Opinion in Chemical Biology, 2021 Bioluminescence (BL) relies on the enzymatic reaction between luciferase, a substrate conventionally named luciferin, and various cofactors. BL imaging has become a widely used technique to interrogate gene expression and cell fate, both in small and large animal models of research.
Zambito, Giorgia +2 more
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Multicomponent Bioluminescence Imaging with Naphthylamino Luciferins. [PDF]
Chembiochem, 2021 AbstractBioluminescent tools have been used for decades to image processes in complex tissues and preclinical models. However, few distinct probes are available to probe multicellular interactions. We and others are addressing this limitation by engineering new luciferases that can selectively process synthetic luciferin analogues.
Brennan CK +3 more
europepmc +5 more sources
Frontiers in Bioengineering and Biotechnology, 2019 Early detection of tumors is today a major challenge and requires sensitive imaging methodologies coupled with new efficient probes. In vivo optical bioluminescence imaging has been widely used in the field of preclinical oncology to visualize tumors and
Fabiane Sônego +8 more
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