Results 221 to 230 of about 63,349 (279)

An in vivo BSL-2 model for henipavirus infection based on bioluminescence imaging of recombinant Cedar virus replication in mice. [PDF]

Front Chem Biol
Huaman C, Clouse C, Rader M, Yan L, Bai S, Gunn BM, Amaya M, Laing ED, Broder CC, Schaefer BC.   +9 more
europepmc   +1 more source

Engineered TIGIT‐Blockade Membrane Vesicles Synergize with Microwave Ablation to Mediate Liver Metastases Eradication

Advanced Science, EarlyView.
Microwave ablation (MWA) represents a highly effective and clinically significant therapeutic modality for the treatment of liver metastases. This study develops engineered cell membrane vesicles to specifically target the transition zone of MWA for liver metastases. This strategy can inhibit VEGF‐mediated immunosuppression, block CD155/TIGIT signaling
Shaoyue Li, Weichen Xu, Yuting Shen, Xuexia Shan, Jiawei Sun, Shisi Ding, Xiaodong Hou, Shaoning Zhang, Zhiyuan Niu, Taixia Wang, Xin Guan, Xiao Li, Weiwei Ren, Dou Du, Huixiong Xu, Wenwen Yue, Liping Sun   +16 more
wiley   +1 more source

In vivo bioluminescence imaging of the intracerebral fibroin-controlled AAV-α-synuclein diffusion for monitoring the central nervous system and peripheral expression. [PDF]

Sci Rep
Mazzocco C, Genevois C, Li Q, Doudnikoff E, Dutheil N, Leste-Lasserre T, Arotcarena ML, Bezard E.   +7 more
europepmc   +1 more source

GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier, Mayher Kaur, Milena Chaufan, Felix‐Levin Hormann, Luiza Martins Nascentes Melo, Mario Palma, Jordan Torpey, Yanshan Liang, Alanis Carmona, Cameron Fraser, Midori Flores, Krystina J. Szylo, Mahsa Yavari, Sheng Hui, Alpaslan Tasdogan, Sven Heiles, Jessalyn M. Ubellacker   +16 more
wiley   +1 more source

Bioluminescence imaging reveals enhanced SARS-CoV-2 clearance in mice with combinatorial regimens. [PDF]

iScience
Ullah I, Escudie F, Scandale I, Gilani Z, Gendron-Lepage G, Gaudette F, Mowbray C, Fraisse L, Bazin R, Finzi A, Mothes W, Kumar P, Chatelain E, Uchil PD.   +13 more
europepmc   +1 more source

Bioluminescence imaging of Cyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung

, 2023
Veland N, Gleneadie H, Brown K, Sardini A, Pombo J, Dimond A, Burns V, Sarkisyan K, Schiering C, Webster Z, Merkenschlager M, Fisher A.   +11 more
europepmc   +1 more source

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

Advanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan, Weijia Li, Wenxue Huang, Jilin Wu, Yao Yu, Yiyao Huang, Lin Yang, Ming Xie, Qishen Yang, Jun Zheng, Yuexuan Zhu, Qi Sun, Biao Li, Leqian Li, Zongwei Wang, Jie Zhao, Peng Wu, Bisheng Cheng   +17 more
wiley   +1 more source

Multicomponent Bioluminescence Imaging with a π-Extended Luciferin. [PDF]

J Am Chem Soc, 2020
Yao Z, Zhang BS, Steinhardt RC, Mills JH, Prescher JA.   +4 more
europepmc   +1 more source

A LDH‐Based Supramolecular Photosensitizer‐Functionalized Bioactive Glass Scaffold for Integrated Postoperative Osteosarcoma Recurrence Prevention and Bone Regeneration

Advanced Science, EarlyView.
An intercalation assembly strategy is proposed to construct a novel LDH‐based supramolecular photosensitizer, which exhibits outstanding reactive oxygen species generation activity under 1270 nm laser irradiation. The deposition of supramolecular photosensitizer onto the surface of bioactive glass scaffolds results in the development of an innovative ...
Tao Wang, Yixin Bian, Tingting Hu, Mengyang Li, Yuqin Tan, Yu Yang, Xiaolan Jian, Xisheng Weng, Chaoliang Tan, Ruizheng Liang   +9 more
wiley   +1 more source

Bioluminescence imaging ofCyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung

, 2023
Veland N, Gleneadie HJ, Brown KE, Sardini A, Pombo J, Dimond A, Burns V, Sarkisyan K, Schiering C, Webster Z, Merkenschlager M, Fisher AG.   +11 more
europepmc   +1 more source