Results 91 to 100 of about 8,042,386 (212)

Luminescence-Resonance-Energy-Transfer-Based Luminescence Nanoprobe for In Situ Imaging of CD36 Activation and CD36–oxLDL Binding in Atherogenesis

, 2019
Macrophage foam cell formation mediated by CD36 receptor dependent internalization of oxidized low-density lipoprotein (oxLDL) is an important hallmark of early atherosclerosis.
Wen Gao, Bo Tang (23472), Zhenhua Liu, Huazhen Yang, Wenhua Cao, Zhenhua Liu (335797), Yuhui Sun (3913441), Lili Tong (1781044), Yuhui Sun, Bo Tang, Huazhen Yang (6413597), Wen Gao (414330), Wenhua Cao (3913444), Lili Tong   +13 more
core   +1 more source

Bioluminescence in dinoflagellates – diversity, molecular phylogeny and field ecology

, 2011
Marine dinoflagellates are an ecologically important group of protists within the plankton, performing key process such as photosynthesis, heterotrophy and toxin production.
Valiadi, Martha
core   +1 more source

Confirmation of SGIp1: endophilin interaction using bioluminescence resonance energy transfer (BRET)

, 2004
Confirmation of SGIp1: endophilin interaction using bioluminescence resonance energy transfer ...
Kristy Bolton (13077711), Gregory Collier (13049697), Matthew Prior (13055622), Richard Fahey (13049820), L Kerr-Bayles (13281264), Ken Walder (13099344), J Trevaskis (13280241), K Whitecross (13279590)   +7 more
core  

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Measuring GPCR stoichiometry using types-1, -2, and -3 bioluminescence resonance energy transfer-based assays

, 2019
How G protein-coupled receptors are assembled is a matter of considerable interest owing in large part to their remarkable pharmacological importance.
James, John R., James H. Felce, John R. James, Felce, James H., Simon J. Davis, Davis, Simon J.   +5 more
core   +1 more source

Glycosylated dendrimer nanoamplifiers hijack DNA damage‐immune crosstalk for enhanced dual‐track therapy of orthotopic glioblastoma

BMEMat, EarlyView.
A glycosylated dendrimer nanoamplifier hijacks DNA damage‐immune crosstalk for enhanced radio‐immunotherapy of glioblastoma. The responsive release of demethylcantharidin simultaneously blocks repair‐mediated resistance by inhibiting DNA repair and overcomes adaptive immune resistance.
Cong Song, Binghan Liu, Junjie Liu, Ce Li, Wenqing Man, Xurui Sun, Chang Yuan, Yanjun Wang, Hong Pan, Shuanglian Wang, Zhiming Zheng   +10 more
wiley   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

BMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue, Hai Cai, Ying Sun, Yaxin Ma, Siyuan Liu, Jinying Zhu, Yan Chen, Xuemei Zeng, Shuangqian Yan   +8 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Red fluorescent protein-aequorin fusions as improved bioluminescent Ca2+ reporters in single cells and mice.

PLoS ONE, 2011
Bioluminescence recording of Ca(2+) signals with the photoprotein aequorin does not require radiative energy input and can be measured with a low background and good temporal resolution.
Adil Bakayan, Cecilia F Vaquero, Fernando Picazo, Juan Llopis   +3 more
doaj   +1 more source

Channel‐trap coupled charge modulation in sulfur‐vacancy‐rich nanotransducer for enhanced dual‐mode cancer catalytic therapy

BMEMat, EarlyView.
Sulfur vacancy‐rich ZnS–NCx heterojunctions are engineered as dual‐function nanotransducers, in which channel‐trap‐coupled electronic pathways enable efficient capture and transport of ultrasound‐induced piezoelectrons. This vacancy‐mediated regulation simultaneously enhances sonodynamic activity and biomimetic POD/GSHOx catalysis, triggering a self ...
Songjing Zhong, Zeyu Zhang, Wenting Chen, Quanhong Hu, Hongyi Sun, Ruidong Yin, Qinyu Zhao, Hongbo Fan, Yuanbo Cui, Yuxuan Zhang, Linlin Li   +10 more
wiley   +1 more source