Results 101 to 110 of about 7,863 (172)

The Natural Quassinoid Brusatol Enhances Venetoclax Efficacy and Overcomes Resistance in Myeloid Leukemias

Cancer Science, Volume 117, Issue 8, Page 2274-2288, August 2026.
Schematic illustration of the mechanisms by which the natural quassinoid brusatol induces apoptosis in myeloid leukemias and enhances venetoclax efficacy via p53‐dependent apoptosis and mitochondrial dysfunction. ABSTRACT While venetoclax‐based combinations have shown promising results in acute myeloid leukemia (AML), the remission duration is ...
Shin‐ichiro Kawaguchi, Kazuya Sato, Junko Izawa, Norihito Takayama, Hiroko Hayakawa, Ken Suzaki, Susumu Goyama, Chiyoko Kato, Eiji Sakashita, Kaoru Tominaga, Hitoshi Endo, Yoshinobu Kanda   +11 more
wiley   +1 more source

Identification of Pyrazolidine‐3‐One Derivatives as a Novel Structural Scaffold for ATP Synthase Inhibitors

ChemMedChem, Volume 21, Issue 14, 29 July 2026.
Following the discovery of oxadiazin‐5‐ones as partial inhibitors of the ATP synthase, we herein report the synthesis of a library of pyrazolidine‐3‐ones and pyrazol‐3‐ones, designed by reducing the six‐membered N–N heterocycles to five‐membered rings.
Lisa Reichert, Aro Delparente, Ida R. Hipfinger, Lukas Reininger, Ana Pinto Castro, Daniel J. Hubin, Roger Schibli, Amy E. Fraley, Linjing Mu   +8 more
wiley   +1 more source

Predicting response to platinum and non-platinum drugs through bioluminescence resonance energy transfer (BRET) based bio-molecular interactions in platinum resistant epithelial ovarian cancer. [PDF]

Transl Oncol, 2021
Bishnu A, Mehrotra M, Dhadve A, Dimri S, De A, Ray P.   +5 more
europepmc   +1 more source

Effects of radiofrequency field exposure on proteotoxic-induced and heat-induced HSF1 response in live cells using the bioluminescence resonance energy transfer technique. [PDF]

Cell Stress Chaperones, 2021
Poque E, Ruigrok HJ, Arnaud-Cormos D, Habauzit D, Chappe Y, Martin C, De Gannes FP, Hurtier A, Garenne A, Lagroye I, Le Dréan Y, Lévêque P, Percherancier Y.   +12 more
europepmc   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Experimental determination of the bioluminescence resonance energy transfer (BRET) Förster distances of NanoBRET and red-shifted BRET pairs. [PDF]

Anal Chim Acta X, 2020
Weihs F, Wang J, Pfleger KDG, Dacres H.
europepmc   +1 more source

Bioluminescent sentinel plants enable autonomous diagnostics of viral infections

Nature Communications
Plants engineered with synthetic genetic programs can transform how we monitor and manage the extension of crop pests and diseases. Here, we establish a bioluminescent platform in Nicotiana benthamiana for autonomous viral sensing based on the fungal ...
Camilo Calvache, Marta Rodriguez-Rodriguez, Victor Vazquez-Vilriales, Elena Garcia-Perez, Aubin Fleiss, Mustafá Ezzeddin-Ayoub, Fabio Pasin, José-Antonio Daròs, Karen S. Sarkisyan, Diego Orzaez, Marta Vazquez-Vilar   +10 more
doaj   +1 more source

Real‐Time Visualization of Isoform‐Specific RAF‐KRAS Interactions in Living Cells Using FRET‐BRET Hybrid Biosensors

Advanced Science
The RAS–RAF–MEK–ERK signaling cascade is a central component of the mitogen‐activated protein kinase (MAPK) pathway, regulating cell proliferation, differentiation, and survival, and is frequently dysregulated in cancer.
Jeong‐Min Go, Dahee Lee, Minji Kim, Kiseok Han, Gyuho Choi, ChanHui Song, Sanghyun Ahn, Yerim Lee, Jinyoung Lee, Yingxiao Wang, Jung‐Soo Suh, Hwayoung Yun, Tae‐Jin Kim   +12 more
doaj   +1 more source

Multiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism. [PDF]

Adv Sci (Weinh), 2020
Wu AY, Sung YC, Chen YJ, Chou ST, Guo V, Chien JC, Ko JJ, Yang AL, Huang HC, Chuang JC, Wu S, Ho MR, Ericsson M, Lin WW, Cheung CHY, Juan HF, Ueda K, Chen Y, Lai CP.   +18 more
europepmc   +1 more source

Bioluminescence Resonance Energy Transfer: Techniques and Potential

, 2005
MOHAMMED SOUTTO, YAO XU, CARL H. JOHNSON
openaire   +1 more source