Results 41 to 50 of about 2,411,306 (333)

Biomarkers of coronary endothelial health: correlation with invasive measures of collateral function, flow and resistance in chronically occluded coronary arteries and the effect of recanalization [PDF]

open access: yes, 2016
Objectives: In the presence of a chronically occluded coronary artery, the collateral circulation matures by a process of arteriogenesis; however, there is considerable variation between individuals in the functional capacity of that collateral network ...
Alamgir, Farquad   +6 more
core   +1 more source

Claudin18.2 is a novel molecular biomarker for tumor-targeted immunotherapy

open access: yesBiomarker Research, 2022
The claudin18.2 (CLDN18.2) protein, an isoform of claudin18, a member of the tight junction protein family, is a highly selective biomarker with limited expression in normal tissues and often abnormal expression during the occurrence and development of ...
Weijie Cao   +6 more
semanticscholar   +1 more source

Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial. [PDF]

open access: yes, 2017
More efficacious treatment regimens are needed for tuberculosis, however, drug development is impeded by a lack of reliable biomarkers of disease severity and of treatment effect. We conducted a directed screen of host biomarkers in participants enrolled
Barbero, S   +14 more
core   +2 more sources

Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium [PDF]

open access: yes, 2020
Importance: There is potential scientific and clinical value in validation of objective biomarkers for sport-related concussion (SRC). Objective: To investigate the association of acute-phase blood biomarker levels with SRC in collegiate athletes.
Broglio, Steven P.   +26 more
core   +1 more source

Toward a Topology-Based Therapeutic Design of Membrane Proteins: Validation of NaPi2b Topology in Live Ovarian Cancer Cells

open access: yesFrontiers in Molecular Biosciences, 2022
NaPi2b is a sodium-dependent phosphate transporter that belongs to the SLC34 family of transporters which is mainly responsible for phosphate homeostasis in humans.
Leisan Bulatova   +8 more
doaj   +1 more source

Patient-derived organoids as a predictive biomarker for treatment response in cancer patients

open access: yesnpj Precision Oncology, 2021
Effective predictive biomarkers are needed to enable personalized medicine and increase treatment efficacy and survival for cancer patients, thereby reducing toxic side effects and treatment costs.
G. Wensink   +6 more
semanticscholar   +1 more source

Atezolizumab plus bevacizumab combination enables an unresectable hepatocellular carcinoma resectable and links immune exclusion and tumor dedifferentiation to acquired resistance

open access: yesExperimental Hematology & Oncology, 2021
We reported a patient with unresectable hepatocellular carcinoma (HCC) who initially received 15 cycles of atezolizumab plus bevacizumab combination and had best tumor response of partial response, but later experienced disease progression.
Yulei Wang   +6 more
doaj   +1 more source

A Magnetic Bead-Based Sensor for the Quantification of Multiple Prostate Cancer Biomarkers. [PDF]

open access: yes, 2015
Novel biomarker assays and upgraded analytical tools are urgently needed to accurately discriminate benign prostatic hypertrophy (BPH) from prostate cancer (CaP).
Brooks, James D   +7 more
core   +4 more sources

HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia. [PDF]

open access: yes, 2019
IntroductionPneumonia is an important cause of morbidity and mortality in persons living with human immunodeficiency virus (HIV) infection. How immune activation differs among HIV-infected and HIV-uninfected adults with pneumonia is unknown.MethodsThe ...
Byanyima, Patrick   +16 more
core   +2 more sources

miR-21: a non‐specific biomarker of all maladies

open access: yesBiomarker Research, 2021
miRNA-21 is among the most abundant and highly conserved microRNAs (miRNAs) recognized. It is expressed in essentially all cells where it performs vital regulatory roles in health and disease.
A. Jenike, M. Halushka
semanticscholar   +1 more source

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