Periostin as a biomarker of airway inflammation [PDF]
, 2016 No abstract ...
Johnstone, Steven, McSharry, Charles
core +1 more source
Computational modelling of the behaviour of biomarker particles of colorectal cancer in fecal matter [PDF]
, 2019 Colorectal adenocarcinoma is one of the carcinogenic diseases that is increasing the morbidity and mortality rates worldwide. The disease initially occurs through the segregation of biomarker substances in the human system without manifesting symptoms ...
Hoyos, L., Suárez, G., Vallejo, E.
core
Development of PancRISK, a urine biomarker-based risk score for stratified screening of pancreatic cancer patients [PDF]
, 2019 © The Author(s) 2019. Published by Springer Nature on behalf of Cancer Research UK.BACKGROUND: An accurate and simple risk prediction model that would facilitate earlier detection of pancreatic adenocarcinoma (PDAC) is not available at present.
Blyuss, Oleg +7 more
core +3 more sources
Test for Incremental Value of New Biomarkers Based on OR Rules [PDF]
arXiv, 2018 In early detection of disease, a single biomarker often has inadequate classification performance, making it important to identify new biomarkers to combine with the existing marker for improved performance. A biologically natural method to combine biomarkers is to use logic rules, e.g. the OR/AND rules.
arxiv
Intrathecal enzyme replacement for Hurler syndrome: biomarker association with neurocognitive outcomes. [PDF]
, 2019 PurposeAbnormalities in cerebrospinal fluid (CSF) have been reported in Hurler syndrome, a fatal neurodegenerative lysosomal disorder. While no biomarker has predicted neurocognitive response to treatment, one of these abnormalities, glycosaminoglycan ...
Dickson, Patricia I +12 more
core
Molecular characterization of breast cancer CTCs associated with brain metastasis
Nature Communications, 2017 Characterization of CTCs derived from breast cancer patients with brain metastasis (BCBM) may allow for early diagnosis of brain metastasis and/or help for treatment choice and its efficacy.
Debasish Boral +10 more
doaj +1 more source
Resting-state functional connectivity-based biomarkers and functional MRI-based neurofeedback for psychiatric disorders: a challenge for developing theranostic biomarkers [PDF]
arXiv, 2017 Psychiatric research has been hampered by an explanatory gap between psychiatric symptoms and their neural underpinnings, which has resulted in poor treatment outcomes. This situation has prompted us to shift from symptom-based diagnosis to data-driven diagnosis, aiming to redefine psychiatric disorders as disorders of neural circuitry.
arxiv
The potential of glycomics as prognostic biomarkers in liver disease and liver transplantation [PDF]
, 2019 The study of glycomics is a novel and fascinating approach for the development of biomarkers. It has become clear that in the field of liver disease specific glycomic patters are present in specific disease states, which has led to the development of ...
Callewaert, Nico +3 more
core
Conditional Screening for Ultra-high Dimensional Covariates with Survival Outcomes [PDF]
arXiv, 2016 Identifying important biomarkers that are predictive for cancer patients' prognosis is key in gaining better insights into the biological influences on the disease and has become a critical component of precision medicine. The emergence of large-scale biomedical survival studies, which typically involve excessive number of biomarkers, has brought high ...
arxiv
Graph-Based Biomarker Discovery and Interpretation for Alzheimer's Disease [PDF]
arXivEarly diagnosis and discovery of therapeutic drug targets are crucial objectives for the effective management of Alzheimer's Disease (AD). Current approaches for AD diagnosis and treatment planning are based on radiological imaging and largely inaccessible for population-level screening due to prohibitive costs and limited availability. Recently, blood
arxiv