Results 61 to 70 of about 2,936,789 (384)

Turnover of type I and III collagen predicts progression of idiopathic pulmonary fibrosis

Respiratory Research, 2021
Background Idiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of fibrillar collagens in the alveolar space resulting in reduced pulmonary function and a high mortality rate.
H. Jessen, N. Hoyer, T. S. Prior, P. Frederiksen, M. A. Karsdal, D. J. Leeming, E. Bendstrup, J. M. B. Sand, S. B. Shaker   +8 more
doaj   +1 more source

Pan-tumor genomic biomarkers for PD-1 checkpoint blockade–based immunotherapy

Science, 2018
Mining immunotherapy clinical trials Clinical trial data can provide a wealth of information about how drugs work. Yet such information often belongs to pharmaceutical companies and is rarely accessible to the scientific community at large.
R. Cristescu, R. Mogg, M. Ayers, Andrew Albright, E. Murphy, J. Yearley, Xinwei Sher, Xiao Qiao Liu, Hongchao Lu, M. Nebozhyn, Chunsheng Zhang, J. Lunceford, A. Joe, Jonathan C Cheng, A. Webber, N. Ibrahim, E. Plimack, P. Ott, T. Seiwert, A. Ribas, T. Mcclanahan, J. Tomassini, A. Loboda, D. Kaufman   +23 more
semanticscholar   +1 more source

Biomarkers in Pain

Biomedicines, 2023
The focus of this Special Issue on Biomedicines is on the value of “Biomarkers in Pain” from a broad perspective [...]
Anders Larsson, Emmanuel Bäckryd, Mats Eriksson   +2 more
openaire   +5 more sources

Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men [PDF]

, 2009
Aims: The extent to which hemostatic and inflammatory biomarkers are related to angina pectoris as compared with myocardial infarction (MI) remains uncertain.
Lennon, L, Lowe, GD, Rumley, A, Shaper, AG, Wannamethee, SG, Whincup, PH   +5 more
core   +1 more source

Collagens and Cancer associated fibroblasts in the reactive stroma and its relation to Cancer biology

Journal of Experimental & Clinical Cancer Research, 2019
The extracellular matrix (ECM) plays an important role in cancer progression. It can be divided into the basement membrane (BM) that supports epithelial/endothelial cell behavior and the interstitial matrix (IM) that supports the underlying stromal ...
Neel I. Nissen, Morten Karsdal, Nicholas Willumsen   +2 more
doaj   +1 more source

Association of Systemic Inflammation With Retinal Vascular Caliber in Patients With AIDS. [PDF]

, 2019
PurposeTo evaluate relationships among retinal vascular caliber and biomarkers of systemic inflammation in patients with AIDS.MethodsA total of 454 participants with AIDS had retinal vascular caliber (central retinal artery equivalent and central retinal
Cheu, Ryan, Danis, Ronald P, Hunt, Peter W, Jabs, Douglas A, Jones, Norman, Klatt, Nichole R, Milush, Jeffrey M, Pak, Jeong Won, Trang, Garrett, Van Natta, Mark L   +9 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway

Journal of Experimental & Clinical Cancer Research, 2022
Background Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in ...
Yujia Li, Hui Chen, Qi Yang, Lixin Wan, Jing Zhao, Yuanyuan Wu, Jiaxin Wang, Yating Yang, Menglan Niu, Hongliang Liu, Junqi Liu, Hushan Yang, Shaogui Wan, Yanming Wang, Dengke Bao   +14 more
doaj   +1 more source

Flexible combination of multiple diagnostic biomarkers to improve diagnostic accuracy

, 2015
In medical research, it is common to collect information of multiple continuous biomarkers to improve the accuracy of diagnostic tests. Combining the measurements of these biomarkers into one single score is a popular practice to integrate the collected ...
Fang, Yixin, Rong, Alan, Wang, Junhui, Xu, Tu   +3 more
core   +1 more source

Salivary biomarkers in psychobiological medicine. [PDF]

, 2006
The value of salivary biomarkers for diagnostic and prognostic assessments has become increasingly well established in medicine, pharmacology, and dentistry. Certain salivary components mirror the neuro-endocrine status of the organism.
Chiappelli, Francesco, Iribarren, Francisco Javier, Prolo, Paolo   +2 more
core   +2 more sources