Results 61 to 70 of about 1,313,247 (306)

Freeform Fabrication of Ionomeric Polymer-Metal Composite Actuators [PDF]

, 2005
Ionomeric polymer-metal composite (IPMC) actuators are a type of soft electromechanically active material which offers large displacement, rapid motion with only ~1V stimulus.
Lipson, Hod, Malone, Evan
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Enhanced antibacterial activity and superior biocompatibility of cobalt-deposited titanium discs for possible use in implant dentistry

iScience
Summary: The clinical success of implants depends on rapid osseointegration, and new materials are being developed considering the increasing demand. Considering cobalt (Co) antibacterial characteristics, we developed Co-deposited titanium (Ti) using ...
Vaibhav Madiwal, Bhushan Khairnar, Jyutika Rajwade   +2 more
doaj   +1 more source

Recent advances in surface-functionalised photosensitive antibacterials with synergistic effects

Biosurface and Biotribology, 2019
The alarm has been ringing over the gradually increasing drug-resistant bacteria, which calls for the development of safer antibacterial materials. Photosensitive antibacterials are considered as a promising alternative solution due to their unique light-
Peizi Liao, Jiahao Hu, Huagao Wang, Jinyang Li, Zuowan Zhou, Zuowan Zhou   +5 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Biomedical and microbiological applications of bio-based porous materials: a review [PDF]

, 2017
Extensive employment of biomaterials in the areas of biomedical and microbiological applications is considered to be of prime importance. As expected, oil based polymer materials were gradually replaced by natural or synthetic biopolymers due to their ...
Abdelaal, Cheng Chuah, Ghosh, Gunathilake, Gupta, Jovanović-Malinovska, Kailasapathy, Kazemzadeh Narbat, Kuan Ching, Luqman Abdullah, Mohd, Nedovic, O’brien, Pichatborvonkul, Stolarzewicz, T. Udenni Gunathilake, Yern Ching, Zanjani   +17 more
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Seawater-contaminated ulnar rabbit bone defects repair using 3D-printed β-TCP/vancomycin composite scaffolds

European Cells & Materials
Background: Repairing extensive bone defects following seawater immersion poses a significant challenge for orthopedic surgeons. Recent advancements in three-dimensional (3D) printing technology have demonstrated considerable potential in fabricating ...
HD Lao, D Liu, R Yi, YN Yuan, M Zhao, GS Li, XY Nie, JL Gu, XM Cai, H Li, SE Lin, JJ Zhou   +11 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Extraction of biological hydroxyapatite from bovine bone for biomedical applications [PDF]

, 2020
Current biomedical field demands intensive research on cost-effective and high availability materials to fulfil its various applications. Owing to its similar characteristic to human bone, biological hydroxyapatite (HAp) has been used as an alternative ...
A. Latif, A.F., Abdullah, H.Z., Idris, M.I., Lee, T.C., Mohd Pu"ad, N.A.S, Muhamad, M.S, Ramli, N.D.   +6 more
core   +1 more source