Results 71 to 80 of about 466,709 (358)

Six questions on the construction of ontologies in biomedicine [PDF]

open access: yes, 2005
(Report assembled for the Workshop of the AMIA Working Group on Formal Biomedical Knowledge Representation in connection with AMIA Symposium, Washington DC, 2005.) Best practices in ontology building for biomedicine have been frequently ...
Burgun, A.   +11 more
core  

Molecularly Imprinted Nanomaterials with Stimuli Responsiveness for Applications in Biomedicine

open access: yesMolecules, 2023
The review aims to summarize recent reports of stimuli-responsive nanomaterials based on molecularly imprinted polymers (MIPs) and discuss their applications in biomedicine.
Yan Zhang   +5 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effects of omega-3 fatty acids on arterial stiffness in patients with hypertension: a randomized pilot study. [PDF]

open access: yes, 2015
BackgroundOmega-3 fatty acids prevent cardiovascular disease (CVD) events in patients with myocardial infarction or heart failure. Benefits in patients without overt CVD have not been demonstrated, though most studies did not use treatment doses (3.36 g)
Beaty, Brenda   +5 more
core   +1 more source

Cellulose-Based Nanomaterials Advance Biomedicine: A Review

open access: yesInternational Journal of Molecular Sciences, 2022
There are various biomaterials, but none fulfills all requirements. Cellulose biopolymers have advanced biomedicine to satisfy high market demand and circumvent many ecological concerns.
H. Abdelhamid, A. Mathew
semanticscholar   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Sweet Taste Preference: Relationships with Other Tastes, Liking for Sugary Foods and Exploratory Genome-Wide Association Analysis in Subjects with Metabolic Syndrome

open access: yesBiomedicines, 2021
Taste perception and its association with nutrition and related diseases (type 2 diabetes, obesity, metabolic syndrome, cardiovascular, etc.) are emerging fields of biomedicine.
Rebeca Fernández-Carrión   +10 more
doaj   +1 more source

The Role of Costimulatory Receptors of the Tumour Necrosis Factor Receptor Family in Atherosclerosis [PDF]

open access: yes, 2011
Atherosclerosis is a chronic inflammatory disease that is mediated by both the innate and adaptive immune responses. T lymphocytes, that together with B cells are the cellular effectors of the adaptive immune system, are currently endowed with crucial ...
Antunes, RF, Dumitriu, IE, Kaski, JC
core   +3 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Objets-frontière à l’épreuve

open access: yesRevue d'anthropologie des connaissances, 2009
This paper analyzes the creation of a research collective around a gene-therapy clinical trial thanks to the concept of boundary-object. It describes the scientific, organizational and regulation dimensions of the trial, and analyzes the different ...
Martin Rémondet
doaj   +1 more source

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