Results 81 to 90 of about 406,090 (330)

Progress and applications of quantum precision measurement based on SERF effect

open access: yesFrontiers in Physics, 2022
With the development of quantum precision measurement technology, measurement methods based on magnetic, optical and atomic interactions have started to receive widespread attention.
Yueyang Zhai   +5 more
doaj   +1 more source

Evaluation of a novel virtual screening strategy using receptor decoy binding sites [PDF]

open access: yes, 2016
Virtual screening is used in biomedical research to predict the binding affinity of a large set of small organic molecules to protein receptor targets.
Kukol, A.   +3 more
core   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Nanoinformatics: developing new computing applications for nanomedicine [PDF]

open access: yes, 2012
Nanoinformatics has recently emerged to address the need of computing applications at the nano level. In this regard, the authors have participated in various initiatives to identify its concepts, foundations and challenges.
Alberto Anguita   +58 more
core   +7 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Culture and carelessness: Constituting disability in South India [PDF]

open access: yes, 2012
This is the author's accepted manuscript. The final published article is available from the link below.Professional and lay explanations of disability, collected via interviews and participant-observation during fieldwork in Hyderabad, South India ...
Allen   +37 more
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Magnetic Nanotransducers in Biomedicine

open access: yesChemistry – A European Journal, 2017
AbstractOwing to their abilities to identify diseased conditions, to modulate biological processes, and to control cellular activities, magnetic nanoparticles have become one of the most popular nanomaterials in the biomedical field. Targeted drug delivery, controlled drug release, hyperthermia treatment, imaging, and stimulation of several biological ...
Agostina Grillone   +2 more
openaire   +2 more sources

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