Results 131 to 140 of about 143,872 (300)
Full‐Length FUS Protein Condensates Adopt a Domain‐Preferential Spatial Architecture
AggregateBiomolecular condensates play crucial roles in cellular physiology and are implicated in neurodegenerative diseases and cancer. However, the mechanisms governing their formation and spatial organization remain poorly understood, largely due to technical ...
Si‐Cheng Tong +5 more
doaj +1 more source
Statistical mechanics models in protein association problems [PDF]
Doctor of PhilosophyDepartment of PhysicsJeremy D. SchmitProtein-Protein interactions can lead to disordered states such as precipitates or gels, or to ordered states such as crystals or microtubules.
Ramallo, Nelson Javier
core
On the reactivity of zinc hydroxide acetate dihydrate in ethanol [PDF]
, 2013 Zinc hydroxide acetate dihydrate, Zn5(OH)8(CH 3CO2)2·2H2O, reacts in ethanol at room temperature to yield a mixture of zinc oxide and anhydrous zinc acetate. The process is driven by dehydration of the starting salt.
Cortie, MB +3 more
core +1 more source
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
Advances in Physics: XBiomolecular condensates are integral to processes underlying cellular function and dysfunction, and they also present a versatile platform for engineering living cells.
M. Julia Maristany +5 more
doaj +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
Advanced Science, EarlyView.ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation
Advanced Science, EarlyView.Nanoplastics are pervasive environmental contaminants with potentially profound implications for human health. Emerging evidence suggests a possible link between nanoplastic exposure and neurodegeneration, a key driver of ageing and dementia, yet causality remains unresolved.
Yuhuan Li +5 more
wiley +1 more source
Sensing and Filtering Environmental Fluctuations: The Case of Biomolecular Condensates in Plants
Advanced Science, EarlyView.The diversity of plant condensates reflects constraints of sessile organisms to coordinate postembryonic development with environmental adaptation. This review examines how plants employ condensates to integrate temperature, light, redox, and nutrient signals.
Panagiotis N. Moschou, Dorothee Staiger
wiley +1 more source
CellsAlzheimer’s disease (AD) is marked by the pathological aggregation of amyloid β (Aβ) and tau proteins. Emerging research reveals that these proteins undergo liquid–liquid phase separation (LLPS), forming biomolecular condensates that promote aggregation ...
Urszula Kochman +6 more
doaj +1 more source
Streamlined V3.5+ Electrolyte Production by Leveraging Chemical and Catalytic Reductions
Advanced Energy Materials, EarlyView.A tuned catalytic process for V3.5+ electrolyte production is shown to streamline the conventional chemical‐to‐catalytic sequence by extending catalysis into the rate‐determining reduction regime. This study shows that initiating catalysis in this regime shortens the overall production time by 67% based on rigorous thermodynamic and kinetic analysis of
Kyunghwa Seok +2 more
wiley +1 more source