Results 131 to 140 of about 116,047 (273)
Biomolecular condensates in Hippo pathway regulation
Journal of Zhejiang University-SCIENCE BHippo signaling is a highly conserved pathway central to diverse cellular processes. Dysregulation of this pathway not only leads to developmental abnormalities but is also closely related to the occurrence and progression of various cancers. Recent studies have uncovered that, in addition to the classical signaling cascade regulation, biomolecular ...
Yangqing Shao +3 more
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Emerging experimental methods to study the thermodynamics of biomolecular condensate formation
The formation of biomolecular condensates in vivo is increasingly recognized to underlie a multitude of crucial cellular functions. Furthermore, the evolution of highly dynamic protein condensates into progressively less reversible assemblies is thought ...
Buell, Alexander K., Ray, Soumik
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Investigation of biomolecular condensate formation in the cellular response to genotoxic stress
Cells are constantly exposed to endogenous and environmental stressors, and must mount an appropriate response in order to maintain health and function. Biomolecular condensates, which are membraneless compartments in the cellular environment, have been ...
Tereshchenko, Maria
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Frontiers in BiophysicsBiomolecular condensates capture the scientific imagination by executing dazzling 3D tours en l’air within the bulk cellular matrix, driven by an intricate theater of multivalent, electrostatic, hydrophobic, and π-driven interactions.
Doris Loh, Russel J. Reiter
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Bone ResearchBiomolecular condensates are membraneless assemblies that concentrate proteins, nucleic acids, and other biomolecules into dynamic cellular compartments.
Qichen Miao +5 more
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Scanning probe microscopy for rheological analysis of biomolecular condensates
STAR ProtocolsSummary: Biomolecular condensates are membrane-less phase-separated assemblies that play key roles in cellular organization. Here, we present a protocol to characterize the full range of rheological properties of condensate droplets, from liquid to solid
Aida Naghilou, Alireza Mashaghi
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Tandem-repeat proteins introduce tuneable properties to engineered biomolecular condensates. [PDF]
The cell's ability to rapidly partition biomolecules into biomolecular condensates is linked to a diverse range of cellular functions. Understanding how the structural attributes of biomolecular condensates are linked with their biological roles can be ...
core +3 more sources
Decoding the genomic landscape of chromatin-associated biomolecular condensates
Nature CommunicationsBiomolecular condensates play a significant role in chromatin activities, primarily by concentrating and compartmentalizing proteins and/or nucleic acids.
Zhaowei Yu +7 more
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The next phase of biomolecular condensate research
Cell ReportsThe Cell Reports team recently attended the Keystone Symposia on Biological Condensates. The meeting was a great opportunity to learn about the latest developments in this exciting area. In this Voices piece, we asked three researchers in the field how the landscape of biomolecular condensate research is evolving.
Mingjie, Zhang +2 more
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Carbon Energy, EarlyView.Converting biomass‐derived syngas into value‐added fuels and chemicals offers a promising route toward carbon neutrality, yet unfavorable H2/COx ratios, elevated CO2 levels, and trace impurities pose persistent obstacles. This review examines strategies spanning syngas conditioning, impurity‐tolerant catalyst development, and integrated process design,
Xuan Bie +7 more
wiley +1 more source