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Pharmacokinetics of Biopharmaceuticals: Their Critical Role in Molecular Design
Biomedicines, 2023 Biopharmaceuticals have developed rapidly in recent years due to the remarkable progress in gene recombination and cell culture technologies. Since the basic structure of biopharmaceuticals can be designed and modified, it is possible to control the ...
Takuo Ogihara +2 more
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Immunogenicity of biopharmaceuticals [PDF]
Nephrology Dialysis Transplantation, 2006 The availability of biopharmaceuticals has been increasing over the past decade and as their patents expire, the emergence of biosimilar agents approaches. The primary issue of concern for the safety of these agents is the potential for immunogenicity.
Michele, Kessler +2 more
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Immune-Modulating Lipid Nanomaterials for the Delivery of Biopharmaceuticals
Pharmaceutics, 2023 In recent years, with the approval of preventative vaccines for pandemics, lipid nanoparticles have become a prominent RNA delivery vehicle. The lack of long-lasting effects of non-viral vectors is an advantage for infectious disease vaccines.
Songhee Kim +3 more
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Potential and Applications of Nanocarriers for Efficient Delivery of Biopharmaceuticals
Pharmaceutics, 2020 During the past two decades, the clinical use of biopharmaceutical products has markedly increased because of their obvious advantages over conventional small-molecule drug products.
Alam Zeb +14 more
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The biopharmaceutical anomaly [PDF]
Nature Biotechnology, 2020 Investment and funding has continued to flow into biotech, unlike most business sectors. But with healthcare and hospital budgets increasingly under pressure, do belt-tightening and consolidation lie ahead? Melanie Senior investigates, with additional reporting by Riku Lahteenmaki.
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Advanced Materials Interfaces, 2023 Spinal cord injury (SCI) has seriously affected the lives of patients and brought economic and medical burdens to society. Biopharmaceuticals, including transplanted cells, growth factors, enzyme drugs, and microRNA, present multidimensional therapeutic ...
Xunqi Zhang +3 more
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Bioethical issues in the development of biopharmaceuticals [PDF]
Filozofija i Društvo, 2012 Development of biopharmaceuticals is a challenging issue in bioethics. Unlike conventional, small molecular weight drugs, biopharmaceuticals are proteins derived from DNA technology and hybrid techniques with complex three dimensional structures ...
Todorović Zoran, Protić Dragana
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Global Profiling of N-Glycoproteins and N-Glycans in the Diatom Phaeodactylum tricornutum
Frontiers in Plant Science, 2021 N-glycosylation is an important posttranslational modification in all eukaryotes, but little is known about the N-glycoproteins and N-glycans in microalgae.
Xihui Xie +17 more
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Biotechnology Journal, 2006 AbstractThe biopharmaceutical industry, whose products are produced mainly by recombinant DNA technology, antibody technologies and cytotechnology, is the most important sector in industrial biotechnology, and is one of the most rapidly growing high‐tech industries.
Xianwen, Hu, Qingjun, Ma, Shuyong, Zhang
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What are biopharmaceuticals? [PDF]
Exploration of Drug ScienceThroughout history, biopharmaceuticals have been essential in addressing health crises and enhancing human well-being. With advancements in genetic engineering, biotechnology, and bioinformatics, the development and approval rates of new ...
Abhay H. Pande +2 more
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