Results 11 to 20 of about 23,130 (165)
Size exclusion chromatography as green support for forced degradation study of adalimumab
Acta Pharmaceutica, 2023 Size exclusion chromatography (SEC) has become a powerful tool for analysing size variants of biologic drugs in their native form. Modern SEC can be defined by the use of chromatographic columns packed with sub-3 µm particles, allowing an increase in ...
Kovačić Jelena +3 more
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COVID-19 Crisis: How Can Plant Biotechnology Help?
Plants, 2021 The emergence of the COVID-19 pandemic has led to significant public health crisis all over the world. The rapid spreading nature and high mortality rate of COVID-19 places a huge pressure on scientists to develop effective diagnostics and therapeutics ...
Md. Jahidul Islam Shohag +5 more
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SAFETY OF BIOLOGICAL PREPARATIONS AND SMALL MOLECULES. ARE THERE ANY DIFFERENCES?
Педиатрическая фармакология, 2013 A considerable number of biopharmaceuticals have recently been introduced into clinical practice. Their role is becoming more and more important in managing various diseases, including incapacitating and life-threatening diseases.
A. S. Kolbin, A. V. Kharchev
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Microbiology Spectrum, 2014 ABSTRACTPlasmids are currently an indispensable molecular tool in life science research and a central asset for the modern biotechnology industry, supporting its mission to produce pharmaceutical proteins, antibodies, vaccines, industrial enzymes, and molecular diagnostics, to name a few key products.
Duarte Miguel F, Prazeres +1 more
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Prospects and Trends in the Brazilian Market for Biologically Sourced Products
Journal of Technology Management & Innovation, 2012 The aim of this paper was to select the most interesting Brazilian biopharmaceuticals, with the best market opportunity for production. The biopharmaceuticals filgrastim, infliximab, somatropin, imiglucerase, betainterferon and factor VIII were selected ...
Luciana da Silva Madeira +2 more
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Pharmaceutics, 2020 Detection and characterization of particles in the visible and subvisible size range is critical in many fields of industrial research. Commercial particle analysis systems have proliferated over the last decade.
Julia Gross-Rother +4 more
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Minicircle Biopharmaceuticals–An Overview of Purification Strategies
Frontiers in Chemical Engineering, 2021 Minicircles are non-viral delivery vectors with promising features for biopharmaceutical applications. These vectors are plasmid-derived circular DNA molecules that are obtained in vivo in Escherichia coli by the intramolecular recombination of a ...
Cláudia P. A. Alves +4 more
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, 2023 Biopharmaceutics, in connection with pharmacokinetics, is the field that investigates and describes everything that happens with a medicinal product and the active substance between the moment of administration, the moment it exerts its action and the moment it is eliminated from the body. Biopharmaceutics connects the physico-chemical properties of an
Frijlink, Henderik +3 more
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Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis
Nature Communications, 2017 Fibroblast Growth Factor 19 (FGF19) neutralizing antibodies inhibit hepatocellular carcinoma (HCC) growth but have safety issues. Here, the authors show that FGF19 promotes HCC by activating STAT3 signalling via IL-6 production and that targeting IL-6 ...
Mei Zhou +4 more
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Biopharmaceuticals—Current Information and New Challenges
Scientia PharmaceuticaBiopharmaceuticals are medical drugs produced by means of biotechnology. In contrast with small-molecule (traditional) drugs, which are usually synthesized chemically, biopharmaceuticals are derived from biological sources, including tissues, cells, or ...
Miroslav Radenković
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