Results 191 to 200 of about 39,175 (290)

Optical method supported by machine learning for dynamics of C‐reactive protein concentrations changes detection in biological matrix samples

Journal of Biophotonics, EarlyView.
The proposed method is based on an optical system supported by machine learning, that allows to monitoring dynamic of C‐reactive protein (CRP) level changes in near‐real time. Monitoring the presence level of CRP in wastewater might be used to track the spread of diseases or identify areas with increased morbidity.
Patryk Sokołowski, Kacper Cierpiak, Małgorzata Szczerska, Maciej Wróbel, Aneta Łuczkiewicz, Sylwia Fudala‐Książek, Paweł Wityk   +6 more
wiley   +1 more source

Reply to Miller et al. Comment on "Hermeling et al. Nano-Dry-Melting: A Novel Technology for Manufacturing of Pharmaceutical Amorphous Solid Dispersions. <i>Pharmaceutics</i> 2022, <i>14</i>, 2145". [PDF]

Pharmaceutics
Hermeling M, Nueboldt C, Heumann R, Hoheisel W, Breitkreutz J.   +4 more
europepmc   +1 more source

Dose-dependent reduction in neointimal hyperplasia following coronary stenting with halofuginone, a collagen synthesis inhibitor Paul C. Keelan, LaDonna J. Camrud, Janis Donovan, Kimberly J. Yuhala, Lior Zelikovich, Debra A. Lewis, Robert S. Schwartz. Mayo Clinic and Foundation, Rochester, MN, Collgard Biopharmaceuticals, Tel Aviv, Israel

, 2001

openalex   +1 more source

Surge Dose^® Formulations of NSAIDs Provide for Ultra-Rapid and Consistent Drug Absorption in Both the Fasted and Fed State as Predicted by Physiologically Based Biopharmaceutics Modelling. [PDF]

Pharmaceutics
Dickinson H, Jiang Z, Dickinson PA, Wilding IR, Elliott GA.   +4 more
europepmc   +1 more source

Strategic Biopharmaceutical Portfolio Development: An Analysis of Constraint‐Induced Implications [PDF]

, 2008
Edmund D. George, Suzanne S. Farid
openalex   +1 more source

Comparing Multi-Label Classification Methods for Provisional Biopharmaceutics Class Prediction. [PDF]

, 2015
Freitas, Alex A., Ghafourian, Taravat, Newby, D.   +2 more
core  

Saliva as a TDM matrix and its application in the model‐informed precision dosing

The Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu, Yujie Wen, Jinxia Lu, Maobai Liu, Xin Luo, Wei Huang, Helin Xie, Yu Cheng, Hongqiang Qiu, Xuemei Wu   +9 more
wiley   +1 more source

Current State and New Horizons in Applications of Physiologically Based Biopharmaceutics Modeling (PBBM): A Workshop Report. [PDF]

Mol Pharm
Tannergren C, Arora S, Babiskin A, Borges L, Chatterjee P, Cheng YH, Dallmann A, Govada A, Heimbach T, Hingle M, Kollipara S, Kotzagiorgis E, Lindahl A, Mackie C, Malamatari M, Mitra A, Moody R, Pepin X, Polli J, Raines K, Rullo G, Sanghavi M, Savkur R, Singh R, Sjögren E, Suarez-Sharp S, Thomas S, Veerasingham S, Wei K, Wu F, Xu Y, Yoon M, Rege B.   +32 more
europepmc   +1 more source

Using generalized quantitative structure–property relationship (QSPR) models to predict host cell protein retention in ion‐exchange chromatography

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Selecting an optimal chromatography resin during biopharmaceutical downstream process development is a great challenge. This is especially the case for recombinant subunit vaccines, where product properties vary greatly and recovery often involves cell lysis, which yields a complex mixture of different host cell materials. Host cell
Tim Neijenhuis, Olivier Le Bussy, Geoffroy Geldhof, Marieke E Klijn, Marcel Ottens   +4 more
wiley   +1 more source

Contribution of Organic Anion Transporter 3 in Delayed Elimination of Methotrexate by Concomitant Administration of Febuxostat. [PDF]

Biopharm Drug Dispos
Ikemura K, Kobayashi S, Wang D, Okuda M.
europepmc   +1 more source