Results 101 to 110 of about 6,578 (240)

Synthesis of 6β-N(5)-Methyl-5,6,7,8-tetrahydro-L-biopterin [PDF]

, 2017
Summary 6β-N(5)-methyl-5.6J,8-tetrahydro-L-biopterin·2 HC1. a new derivate of biological interest, was synthesized from 6β-5,6,7,8-tetrahydro-L-biopteril·2 HC1 and characterized.
Bosshard, Rene, Heizmann, Claus W., Viscontini, Max   +2 more
core  

Cerebrospinal fluid neopterin analysis in neuropediatric patients: establishment of a new cut off-value for the identification of inflammatory-immune mediated processes [PDF]

, 2018
OBJECTIVE: A high level of cerebrospinal fluid (CSF) neopterin is a marker of central nervous system inflammatory-immune mediated processes. We aimed to assess data from 606 neuropediatric patients, describing the clinical and biochemical features of ...
Artuch Iriberri, Rafael, Cambra Lasaosa, Francisco José, Fernández-Ureña, Sergio, Garcia-Cazorla, Àngels, Jordán García, Iolanda, Molero Luis, Marta, Neopterin Workin Group, Ormazabal Herrero, Aida, Serrano, Mercedes   +8 more
core   +1 more source

Attenuation of Biopterin Synthesis Prevents Escherichia coli K1 Invasion of Brain Endothelial Cells and the Development of Meningitis in Newborn Mice [PDF]

, 2012
Muthusamy V. Shanmuganathan, Subramanian Krishnan, Xiaowei Fu, Nemani V. Prasadarao   +3 more
openalex   +1 more source

Oxidative Stress and Pteridines in Pediatric Asthma: Relationship to Exhaled Nitric Oxide

Pteridines, 2012
Fractional exhaled nitric oxide (FeNO) is a useful marker of airway inflammation in asthmatics. Nitric oxide synthase (NOS) requires tetrahydrobiopterin as a cofactor and produces superoxide during NO generation.
Takeda Taisuke, Hamazaki Takashi, Wakahara Ryohei, Fujioka Hiroki, Niihira Shizuhiro, Shintaku Haruo   +5 more
doaj   +1 more source

Pretreatment cognitive and neural differences between sapropterin dihydrochloride responders and non-responders with phenylketonuria [PDF]

, 2017
Sapropterin dihydrochloride (BH4) reduces phenylalanine (Phe) levels and improves white matter integrity in a subset of individuals with phenylketonuria (PKU) known as “responders.” Although prior research has identified biochemical and genotypic ...
Christ, Shawn E, Grange, Dorothy K, Hawks, Zoe, Rutlin, Jerrel, Shimony, Joshua, White, Desiree A   +5 more
core   +4 more sources

Serum biopterin — a novel marker for immune activation during pre-diabetes in the BB rat [PDF]

, 1994
Andrew Davies, A. J. Bone, Terence J. Wilkin, Della Cole, H. Rokos   +4 more
openalex   +1 more source

739 TRANSIENT BIOPTERIN SYNTHETASE DEFICIENCY IN A NEW-BORN WITH PHENYLKETONURIA [PDF]

, 1981
Reuben Matalon, K. Michals, Chinq-Lun Lee, J. C. Nixon   +3 more
openalex   +1 more source

Concentrations of neopterin, biopterin, and cortisol associated with surgical castration of piglets with lidocaine

Czech Journal of Animal Science, 2015
The effect of surgical castration with local anesthesia using lidocaine on neopterin, biopterin, and cortisol blood plasma concentrations in piglets was studied.
P. Maršálek, M. Svoboda, J. Bernardy, V. Večerek   +3 more
doaj   +1 more source

Pharmacokinetics of orally administered tetrahydrobiopterin in patients with phenylalanine hydroxylase deficiency [PDF]

, 2018
Summary: The oral loading test with tetrahydrobiopterin (BH4) is used to discriminate between variants of hyperphenylalaninaemia and to detect BH4-responsive patients.
Blau, N., Demirkol, M., Fiege, B., Fiori, L., Giovannini, M., Gärtner, K., Ozen, I., Thöny, B., Zurflüh, M.   +8 more
core  

The Influence of 2,4-Diamino-6-Hydroxypyrimidine and Food Restriction on Tetrahydrobiopterin Metabolism, Neurotransmitters and Behaviour in the Rat

Pteridines, 1991
Administration of 2,4-diamino-6-hydroxypyrimidine (DAHP) in the diet of rats reduced total biopterins in plasma, brain and liver. The levels of dihydropteridine reductase (DHPR) and the rate of biopterin biosynthesis were unaffected.
Cox J., Armstrong R. A., Blair J. A.
doaj   +1 more source