Results 81 to 90 of about 4,698 (199)

Identification of Transport-critical Residues in a Folate Transporter from the Folate-Biopterin Transporter (FBT) Family*

open access: yesJournal of Biological Chemistry, 2009
The Synechocystis Slr0642 protein and its plastidial Arabidopsis (Arabidopsis thaliana) ortholog At2g32040 belong to the folate-biopterin transporter (FBT) family within the major facilitator superfamily. Both proteins transport folates when expressed in
A. Eudes   +7 more
semanticscholar   +1 more source

Late-stage systemic immune effectors in Plasmodium berghei ANKA infection: biopterin and oxidative stress

open access: yesPteridines, 2015
To investigate the involvement of systemic oxidative stress in the pathogenesis of murine cerebral malaria, mice were infected with the Plasmodium berghei (P. berghei) ANKA 6653 strain.
Dogruman-Al Funda   +4 more
doaj   +1 more source

Inhibitory Effects of Pteridines on the Cytochrome P-450 Enzyme System

open access: yesPteridines, 1997
The effects of 17 different pteridine derivatives on rat liver microsomal cytochrome P-450 catalyzed degradation of aminoantipyrin were studied.
Horejsi Renate   +5 more
doaj   +1 more source

Tetrahydrobiopterin Synthesis in Rat Cardiac Myocytes; An Event Required for Cytokine-induced NO Generation

open access: yesPteridines, 1998
Cardiac myocytes are known to express the high-capacity inducible isoform of nitric oxide (NO) synthase (iNOS). Since tetrahydrobiopterin (BH4) is an essential cofactor for NO formation, we investigated whether BH4 synthesis is required for cytokine ...
Hattori Yoshiyuki   +3 more
doaj   +1 more source

Oxidative Stress and Pteridines in Pediatric Asthma: Relationship to Exhaled Nitric Oxide

open access: yesPteridines, 2012
Fractional exhaled nitric oxide (FeNO) is a useful marker of airway inflammation in asthmatics. Nitric oxide synthase (NOS) requires tetrahydrobiopterin as a cofactor and produces superoxide during NO generation.
Takeda Taisuke   +5 more
doaj   +1 more source

The Influence of 2,4-Diamino-6-Hydroxypyrimidine and Food Restriction on Tetrahydrobiopterin Metabolism, Neurotransmitters and Behaviour in the Rat

open access: yesPteridines, 1991
Administration of 2,4-diamino-6-hydroxypyrimidine (DAHP) in the diet of rats reduced total biopterins in plasma, brain and liver. The levels of dihydropteridine reductase (DHPR) and the rate of biopterin biosynthesis were unaffected.
Cox J., Armstrong R. A., Blair J. A.
doaj   +1 more source

Early Diagnosis of 6-Pyruvoyl-tetrahydropterin Synthase Deficiency

open access: yesPteridines, 1994
6-Pyruvoyl-tetrahydropterin synthase (PTPS) deficiency, which used to be called dihydrobiopterin synthase deficiency, is the most common kind of tetrahydrobiopterin deficiency. Early treatment by administration of tetrahydrobiopterin and neurotransmitter
Shintaku Haruo
doaj   +1 more source

Neopterin In Immunological Reactions In Cancer and In the Brain Possible Involvement of Macrophages and Microglia

open access: yesPteridines, 1995
Neopterin, a compound derived from GTP, is a percursor molecule of biopterin and is an essential cofactor in neurotransmitter synthesis. It has recently reported that in vivo as well as in vitro immune responses are accompaniced by an increased release ...
Sawada Makuto
doaj   +1 more source

Regulation of cortical and peripheral GCH1 expression and biopterin levels in schizophrenia-spectrum disorders.

open access: yesPsychiatry Research, 2018
J. Clelland   +3 more
semanticscholar   +1 more source

Guanosine triphosphate cyclohydrolase I deficiency: a rare cause of hyperphenylalaninemia

open access: yesThe Turkish Journal of Pediatrics, 1999
Tetrahydrobiopterin (BH4) deficiencies are a heterogeneous group of disorders caused by a defect in two of the three enzymes involved in its biosynthesis or in the two recycling enzymes.
T Coşkun   +6 more
doaj  

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