Results 61 to 70 of about 2,891 (172)

Pterin determination in cerebrospinal fluid: state of the art

open access: yesPteridines, 2017
The analysis of pterins in the cerebrospinal fluid (CSF) is mandatory for the etiologic diagnosis of inborn errors of dopamine and serotonin metabolism.
Guibal Pierre   +3 more
doaj   +1 more source

Metabolomic Analysis of Phytophthora parasitica Growth in the Presence of β‐sitosterol Indicates Adaptive Mechanisms Modulated by Sterols

open access: yesJournal of Basic Microbiology, Volume 66, Issue 2, February 2026.
ABSTRACT Phytophthora parasitica is a generalist phytopathogenic oomycete that infects a series of crops with great economic interest, including tomato, tobacco, and citrus species. Sterols are essential lipids in eukaryotic organisms, playing a fundamental role in the structure and function of the cell membrane.
Pâmela Ponce Martins   +7 more
wiley   +1 more source

Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization

open access: yesJournal of Basic Microbiology, Volume 66, Issue 2, February 2026.
ABSTRACT Monascus fungi are valued for their production of Monacolin K (MK), a bioactive compound with recognized lipid‐lowering and multifunctional properties. To enhance MK yield in solid‐state fermentation, this study combined atmospheric and room‐temperature plasma (ARTP) mutagenesis with L‐arginine supplementation.
Chen Yang, Yang Yajing, Hong Housheng
wiley   +1 more source

Late-stage systemic immune effectors in Plasmodium berghei ANKA infection: biopterin and oxidative stress

open access: yesPteridines, 2015
To investigate the involvement of systemic oxidative stress in the pathogenesis of murine cerebral malaria, mice were infected with the Plasmodium berghei (P. berghei) ANKA 6653 strain.
Dogruman-Al Funda   +4 more
doaj   +1 more source

Inhibitory Effects of Pteridines on the Cytochrome P-450 Enzyme System

open access: yesPteridines, 1997
The effects of 17 different pteridine derivatives on rat liver microsomal cytochrome P-450 catalyzed degradation of aminoantipyrin were studied.
Horejsi Renate   +5 more
doaj   +1 more source

Tetrahydrobiopterin Synthesis in Rat Cardiac Myocytes; An Event Required for Cytokine-induced NO Generation

open access: yesPteridines, 1998
Cardiac myocytes are known to express the high-capacity inducible isoform of nitric oxide (NO) synthase (iNOS). Since tetrahydrobiopterin (BH4) is an essential cofactor for NO formation, we investigated whether BH4 synthesis is required for cytokine ...
Hattori Yoshiyuki   +3 more
doaj   +1 more source

Oxidative Stress and Pteridines in Pediatric Asthma: Relationship to Exhaled Nitric Oxide

open access: yesPteridines, 2012
Fractional exhaled nitric oxide (FeNO) is a useful marker of airway inflammation in asthmatics. Nitric oxide synthase (NOS) requires tetrahydrobiopterin as a cofactor and produces superoxide during NO generation.
Takeda Taisuke   +5 more
doaj   +1 more source

The Influence of 2,4-Diamino-6-Hydroxypyrimidine and Food Restriction on Tetrahydrobiopterin Metabolism, Neurotransmitters and Behaviour in the Rat

open access: yesPteridines, 1991
Administration of 2,4-diamino-6-hydroxypyrimidine (DAHP) in the diet of rats reduced total biopterins in plasma, brain and liver. The levels of dihydropteridine reductase (DHPR) and the rate of biopterin biosynthesis were unaffected.
Cox J., Armstrong R. A., Blair J. A.
doaj   +1 more source

Early Diagnosis of 6-Pyruvoyl-tetrahydropterin Synthase Deficiency

open access: yesPteridines, 1994
6-Pyruvoyl-tetrahydropterin synthase (PTPS) deficiency, which used to be called dihydrobiopterin synthase deficiency, is the most common kind of tetrahydrobiopterin deficiency. Early treatment by administration of tetrahydrobiopterin and neurotransmitter
Shintaku Haruo
doaj   +1 more source

Guanosine triphosphate cyclohydrolase I deficiency: a rare cause of hyperphenylalaninemia

open access: yesThe Turkish Journal of Pediatrics, 1999
Tetrahydrobiopterin (BH4) deficiencies are a heterogeneous group of disorders caused by a defect in two of the three enzymes involved in its biosynthesis or in the two recycling enzymes.
T Coşkun   +6 more
doaj  

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