Results 121 to 130 of about 1,078 (162)

Long-term safety of sapropterin in paediatric and adult individuals with phenylalanine hydroxylase deficiency: Final results of the Kuvan® Adult Maternal Paediatric European Registry multinational observational study. [PDF]

open access: yesJ Inherit Metab Dis
Feillet F   +12 more
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Synthesis of (‐)‐Biopterin

Liebigs Annalen der Chemie, 1989
AbstractThe synthesis of (‐)‐biopterin (1) was accomplished by employing (1S,2S)‐1‐(2‐furyl)‐2‐(trityloxy)‐1‐propanol (6), derived from ethyl (S)‐lactate, as building block for the side chain.
Kenji Mori, Haruhiko Kikuchi
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Biosynthesis of Biopterin by Rat Brain

Journal of Neurochemistry, 1982
Abstract: A method for the determination of [14C]biopterin biosynthesis from [14C]guanosine‐5′‐triphosphate by a desalted preparation from rat striatum, based on sequential reverse‐phase and cation‐exchange high performance liquid chromatography, is described.
Gregory Kapatos   +2 more
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Physiological and clinical chemistry of biopterin

Medicinal Research Reviews, 1989
Chimie, dosage de la biopterine. Biosynthese de la tetrahydrobiopterine. Role physiologique de la tetrahydrobiopterine comme cofacteur des monooxygenases necessitant la pterine.
Toshiharu Nagatsu   +2 more
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A new synthesis of biopterin

Journal of the Chemical Society C: Organic, 1969
An unambiguous synthesis of biopterin [2-amino-6-(L-erythro-1,2-dihydroxypropyl)pteridin-4-(3H)-one] is described; based on an improved synthesis of L-neopterin. The synthesis yields biopterin, a naturally occurring pteridine, in a pure, crystalline form without recourse to chromatography. D-Biopterin and D-neopterin are also described.
B. P. Tong   +2 more
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Biopterin and neopterin in human saliva

Life Sciences, 1989
Presence of biopterin and neopterin in human saliva was investigated by HPLC after iodine oxidation in acidic medium. Concentrations of biopterin and neopterin (M +/- SEM) were 1.271 +/- 0.254 and 0.358 +/- 0.075 ng per ml, respectively, in saliva of apparently healthy young male adults, ages 20 to 22 years (n = 9).
Setsuko Katoh   +3 more
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Pteridine diuretics as biopterin antagonists

Biochemical Pharmacology, 1974
Abstract A series of pteridines having varying degrees of diuretic activity were tested for their effects on the growth of the pteridine-requiring flagellate, Crithidia fasciculata . Inhibition of growth was correlated with diuretic activity insofar as compounds devoid of diuretic effects were uninhibitory and active inhibitors were also good to ...
George W. Kidder, Virginia C. Dewey
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ChemInform Abstract: PTERIDINES, LXXV. SYNTHESIS AND PROPERTIES OF BIOPTERIN AND BIOPTERIN ANALOGS

Chemischer Informationsdienst, 1985
AbstractAus dem Desoxy‐arabinose‐hydrazon (II) und den Diaminen ( l) werden Biopterin ( 111a), dessen Dimethyl‐Derivat (IIIc) und Biolumazin (IIIb) hergestellt.
M. Kappel   +2 more
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