Results 11 to 20 of about 1,078 (162)
Insulin Reverses D-Glucose–Increased Nitric Oxide and Reactive Oxygen Species Generation in Human Umbilical Vein Endothelial Cells [PDF]
, 2015 Vascular tone is controlled by the L-arginine/nitric oxide (NO) pathway, and NO bioavailability is strongly affected by hyperglycaemia-induced oxidative stress.
Aguayo, Claudio +7 more
core +1 more source
Global Challenges, Volume 7, Issue 5, May 2023., 2023 Microalgae biomass has tremendous potential as a sustainable source of alternative proteins. Enzymatic processing of microalgae proteins yields structurally diverse peptides with multiple biofunctional properties. This review discusses recent developments in microalgae protein‐derived bioactive peptides relevant in cardiovascular disease management ...
Chukwunonso E. C. C. Ejike +3 more
wiley +1 more source
Effects of endothelin-1 on intracellular tetrahydrobiopterin levels in vascular tissue [PDF]
, 2018 Objective: Tetrahydrobiopterin (BH4) is the essential cofactor of endothelial nitric oxide synthase (eNOS) and intracellular levels of BH4 is regulated by oxidative stress.
Antoniades, Charalambos +6 more
core +2 more sources
Urinary isoxanthopterin as a novel predictor following catheter ablation for atrial fibrillation
Journal of Arrhythmia, Volume 39, Issue 2, Page 159-165, April 2023., 2023 Oxidative stress is known as one of the causes of atrial fibrillation recurrence following catheter ablation; however, representative markers have not been established. In the results of urinary analyses using high‐performance liquid chromatography, urinary isoxanthopterin could be the noninvasive predictor of atrial tachyarrhythmias following catheter
Takahisa Koi +4 more
wiley +1 more source
The role of nutraceuticals in the management of autism [PDF]
, 2013 Autism and related disorders are increasingly prevalent behavioral syndromes of impaired verbal and nonverbal communication and socialization owing to neurodevelopmental abnormalities.
Alanazi, Abdulrahman S.
core +1 more source
Neurological aspects of biopterin metabolism. [PDF]
Archives of Disease in Childhood, 1986 Plasma total biopterin concentration was measured by bioassay in 59 infants with hyperphenylalaninaemia and in 50 children with developmental regression and or movement disorder with normal plasma phenylalanine concentrations. In infants with raised phenylalanine concentrations plasma biopterin concentrations were significantly raised in proportion to ...
R. J. Leeming +3 more
openaire +3 more sources
Protein inhibitor of NOS1 plays a central role in the regulation of NOS1 activity in human dilated hearts [PDF]
, 2016 An essential factor for the production of nitric oxide by nitric oxide synthase 1 (NOS1), major modulator of cardiac function, is the cofactor tetrahydrobiopterin (BH4).
Carnicer, Ricardo +8 more
core +2 more sources
Tetrahydro‐6‐biopterin is associated with tetrahydro‐7‐biopterin in primary murine mast cells [PDF]
FEBS Letters, 1992 Murine bone marrow‐derived mast cells proliferate in response to interleukin 3. In addition to 6‐biopterin, 7‐biopterin was identified in these cells by HPLC analysis of iodine oxidized extracts and by alkaline permanganate oxidation to the 6‐ and 7‐carboxylic acids. 7‐Biopterin comprised 31.9 (± 7.7)% of the total biopterin.
Ziegler, I., Hültner, L.
openaire +4 more sources
First Synthesis of Asperopterin A, an Isoxanthopterin Glycoside from Aspergillus Oryzae [PDF]
, 2013 The key precursor, N-2-(N,N -dimethylaminomethylene)-6-hydroxymethyl-8-methyl-3-[2-(4-nitrophenyl)ethyl]-7-xanthopterin (16) was efficiently prepared from 2,5-diamino-6-methylamino-3H-pyrimidin-4-one (5) and ethyl 3-(tert-butyldimethylsilyloxy)-2 ...
Hanaya, Tadashi, Yamamoto, Hiroshi
core +1 more source
New aspects in biopterin biosynthesis in man [PDF]
FEBS Letters, 1981 Tetrahydrobiopterin is synthesized from guanosine triphosphate (GTP)in several enzymatic steps [1,2]. Details of the pathway of the biopterin biosynthesis in mammals are still unresolved [3]. In rat and human brain the rate-limiting enzyme was GTP cyclohydrolase [2], followed by D-erythro-7,8-dihydroneopterin triphosphate synthetase.
Häusermann, Max +3 more
openaire +4 more sources