Results 81 to 90 of about 71,391 (320)

Mapping molecular pathways for embryonic Sertoli cells derivation based on differentiation model of mouse embryonic stem cells

Stem Cell Research & Therapy, 2020
Background Embryonic Sertoli cells (eSCs) have been known for playing important roles in male reproductive development system. In current studies, eSCs were mainly generated from induced intermediate mesoderm.
Chenze Xu, Yichen Dai, Ali Mohsin, Haifeng Hang, Yingping Zhuang, Meijin Guo   +5 more
doaj   +1 more source

Robust Controlled Degradation of Enzyme Loaded PCL‐Based Fibrous Scaffolds Toward Scarless Skin Tissue Regeneration

Advanced Science, EarlyView.
A novel biodegradable wound dressing (E‐PCLs) based on polycaprolactone (PCL) and an enzyme complex (RHP‐BCL) is developed using a fiber microfluidic electrospinning technique. The dressing achieves complete degradation within 14 days, eliminates microplastic residues, and promotes scar‐free healing (99% in 21 days).
Lingling Fan, Weiliang Dong, Jianqi Lu, Yujia Peng, Bin Xie, Ping Wei, Min Jiang, Su Chen   +7 more
wiley   +1 more source

Microtechnology in Space Bioreactors

CHIMIA, 1999
Space biology is a young and rapidly developing discipline comprising basic research and biotechnology. In the next decades it will play a prominent role in the International Space Station (ISS). Therefore, there is an increasing demand for sophisticated instrumentation to satisfy the requirements of the future projects in space biology.
Isabelle Walther, Bart van der Schoot, Marc Boillat, Otfried Müller, Augusto Cogoli   +4 more
openaire   +4 more sources

Tailored 3D Lattice Microstructures for Enhanced Functionality in Blood‐Gas Exchange

Advanced Science, EarlyView.
Common hollow fiber structures are associated with inhomogeneous flow, leading to many complications in the medical application of extracorporeal membrane oxygenation. Using locally adapted lattice structures, the overall flow distribution can be manipulated.
Kai P. Barbian, Teresa Lemainque, Ina Grunden, Roman Iwa, Bettina Wiegmann, John Linkhorst, Matthias Wessling, Jan Heyer, Ulrich Steinseifer, Michael Neidlin, Sebastian V. Jansen   +10 more
wiley   +1 more source

IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex

Advanced Science, EarlyView.
This study reveals IFITM2 as a key regulator of endocytosis in radial glial cells (RGCs) during brain development. IFITM2's YXXø motif and phosphoinositide‐binding residues (K82/K87) are essential for endosome formation. IFITM2 deficiency disrupts the embryonic cortical neurogenesis, revealing a conserved mechanism linking endocytic dynamics to neural ...
Yuqing Lv, Wenzheng Zou, Lin Li, Shukui Zhang, Jiaqi Liang, Jiali Pu, Jianwei Jiao   +6 more
wiley   +1 more source

Enhancement of cellulase production in Trichoderma reesei RUT-C30 by comparative genomic screening

Microbial Cell Factories, 2019
Background Cellulolytic enzymes produced by the filamentous fungus Trichoderma reesei are commonly used in biomass conversion. The high cost of cellulase is still a significant challenge to commercial biofuel production. Improving cellulase production in
Pei Liu, Aibo Lin, Guoxiu Zhang, Jiajia Zhang, Yumeng Chen, Tao Shen, Jian Zhao, Dongzhi Wei, Wei Wang   +8 more
doaj   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

Advanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang, Shiying Zhang, Irene Shuping Zhao, Xueqi Gan, Yang Zhang   +4 more
wiley   +1 more source

Numerical Solution of a Complete Formulation of Flow in a Perfusion Bone-Tissue Bioreactor Using Lattice Boltzmann Equation Method [PDF]

arXiv, 2011
We report the key findings from numerical solutions of a model of transport within an established perfusion bioreactor design. The model includes a complete formulation of transport with fully coupled convection-diffusion and scaffold cell attachment. It also includes the experimentally determined internal (Poly-L-Lactic Acid (PLLA)) scaffold boundary,
arxiv  

Characterization and Reuse of Lithium‐ion Battery Cathode Material Recovered Through a Bacterial Process

Advanced Energy Materials, EarlyView.
A sustainable bacteria‐based lithium‐ion battery cathode recycling method is optimized using engineering biology. The resulting biomineralized manganese carbonate species is found to be easily converted into an electrode material, via simple calcination.
Virginia Echavarri‐Bravo, Isolde Marsland, Mai‐Britt V. Jensen, Caroline Kirk, Louise E. Horsfall   +4 more
wiley   +1 more source

Competition between biodetoxification fungus and lactic acid bacterium in the biorefinery processing chain for production of cellulosic L-lactic acid

Bioresources and Bioprocessing
Biodetoxification fungus selectively degrades toxic inhibitors generated from pretreatment of lignocellulose without consuming fermentable sugars.
Zhibin Li, Lingxiao Zhang, Niling He, Bin Zhang, Jie Bao   +4 more
doaj   +1 more source