Results 111 to 120 of about 126,870 (331)
Advanced Science, EarlyView.BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou +9 more
wiley +1 more source
Piv study of mixing characteristics in a stirred vessel with a non-Newtonian fluid [PDF]
, 2012 PIV is used to analyze the flow induced by a Rushton turbine in a shear-thinning fluid, at constant input power, constant impeller velocity but different concentrations. The rheology of each shear-thinning fluid is first addressed.
Anne-Archard, Dominique +4 more
core
Principles for Rigorous Design and Application of Synthetic Microbial Communities
Advanced Science, EarlyView.SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang +21 more
wiley +1 more source
Non-GMP plasmid production for transient transfection in bioreactors [PDF]
, 2001 Georg H. Schmid +2 more
openalex +1 more source
Advanced Science, EarlyView.This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu +10 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a conductive‐piezoelectric integrated microstructured conduit for peripheral nerve regeneration. The conduit combines reduced graphene oxide with a piezoelectric nanofiber membrane, enhancing nerve repair through physical guidance, oxidative stress inhibition, and ultrasound‐activated electrical stimulation.
Dong Zhou +9 more
wiley +1 more source
Disposable bioreactors: the current state-of-the-art and recommended applications in biotechnology [PDF]
, 2018 Disposable bioreactors have increasingly been incorporated into preclinical, clinical, and production-scale biotechnological facilities over the last few years.
Eibl, Dieter +3 more
core
Advanced Science, EarlyView.This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh +14 more
wiley +1 more source
Influent Wastewater Microbiota and Temperature Influence Anaerobic Membrane Bioreactor Microbial Community [PDF]
, 2016 Sustainable municipal wastewater recovery scenarios highlight benefits of anaerobic membrane bioreactors (AnMBRs). However, influences of continuous seeding by influent wastewater and temperature on attached-growth AnMBRs are not well understood. In this
Berg, K. J. +2 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Organoid research offers valuable insights into human biology and disease, but reproducibility and scalability remain significant challenges, particularly for epithelial organoids. Here, we present an integrated microfluidic platform that addresses these limitations by enabling high‐throughput generation of uniform hydrogel microparticles ...
Barbora Lavickova +8 more
wiley +1 more source