Results 121 to 130 of about 92,761 (280)

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

Advanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin, Wangqiong Chen, Danlu Yang, Qing Liu, Baolong Bai, Zirui Dai, Xirong Liu, Zirong Zhu, Jie Rang, Liqiu Xia   +9 more
wiley   +1 more source

Editorial: Advanced Bioremediation Technologies and Processes for the Treatment of Synthetic Organic Compounds

Frontiers in Bioengineering and Biotechnology, 2021
Kunal R. Jain, Chirayu Desai, Eric D. van Hullebusch, Datta Madamwar   +3 more
doaj   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

PROPOSAL FOR THE DESIGN OF AN INDUSTRIAL PLANT FOR THE TREATMENT OF SOLID URBAN WASTE FOR THE MUNICIPALITY OF ARANDAS, JALISCO

Ra Ximhai, 2018
One of the biggest problems in cities is the management and disposal of urban solid waste, since large volumes are generated and there is no separation at the generation points.
Norberto Santiago-Olivares, Samuel Íñiguez-Gómez, Javier Isaac Contreras-Ochoa, Guadalupe Jacqueline Hernández-Hernández   +3 more
doaj  

Advances in Bioprocess Engineering for Optimising Chlorella vulgaris Fermentation: Biotechnological Innovations and Applications

Foods
Chlorella vulgaris, a unicellular green microalga, has obtained significant attention due to its high protein content, abundance of bioactive compounds, and broad biotechnological potential.
Ana R. Mendes, Maria P. Spínola, Madalena Lordelo, José A. M. Prates   +3 more
doaj   +1 more source

Relating Methanogen Community Structure and Anaerobic Digester Function [PDF]

, 2015
Much remains unknown about the relationships between microbial community structure and anaerobic digester function. However, knowledge of links between community structure and function, such as specific methanogenic activity (SMA) and COD removal rate ...
Bocher, Benjamin T.W., Cherukuri, Keerthi, Johnson, M., Maki, James, Zitomer, Daniel   +4 more
core   +1 more source

Recent Advances in Sustainable Single‐Atom Catalysts from Biomass and Solid Waste: Design, Synthesis and Applications

Advanced Science, EarlyView.
Biomass‐ and solid waste‐derived sustainable single‐atom catalysts (Sus‐SACs) provide a cost‐effective and renewable approach to catalyst design. This review summarizes precursor selection, including AI‐assisted screening, synthesis strategies with emphasis on ultrafast methods, and advanced characterization techniques.
Hongzhe He, Yuhang Qiu, Ruoqun Zhang, Sasha Yang, Jingwei Wang, Jianglong Yu, Lian Zhang, Ning Chen, Baiqian Dai   +8 more
wiley   +1 more source

Aproximación al cultivo de condrocitos en la Universidad Nacional de Colombia.: Reporte técnico Approach to chondrocytes culture in National University of Colombia.: A technical report

Revista Cubana de Investigaciones Biomédicas, 2010
La pérdida de un tejido o de su función, debido a defectos congénitos, enfermedad o trauma, es uno de los problemas más difíciles, frecuentes y costosos que enfrenta la medicina humana. La degeneración del cartílago articular se conoce como osteoartrosis
Nancy Stella Landínez Parra, Diego Alexander Garzón Alvarado, Carmen Alicia Cardozo de Martínez   +2 more
doaj