Results 61 to 70 of about 92,761 (280)

Multiaxial rotational loading compromises the transition zone of the intervertebral disc: Ex vivo study using next‐generation bioreactors

open access: yesBioengineering & Translational Medicine
Bioreactors have become indispensable tools in spine research, enabling long‐term intervertebral disc culture under controlled biological and mechanical conditions.
Amra Šećerović   +8 more
doaj   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee   +7 more
wiley   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

open access: yesAdvanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu   +4 more
wiley   +1 more source

Experimental laboratory research and evaluation of periodic operation small size bioreactors / Periodinio veikimo mažų matmenų bioreaktorių laboratoriniai eksperimentiniai tyrimai ir vertinimas

open access: yesMokslas: Lietuvos Ateitis, 2016
The investigation device – small size periodic operation bioreactors, which are developed for the production of biogas from different organic, vegetable waste.
Vitalij Kolodynskij, Pranas Baltrėnas
doaj   +1 more source

Minimal time control of fed-batch processes with growth functions having several maxima [PDF]

open access: yes, 2010
We address the issue of minimal time optimal control of fedbatch reactor in presence of complex non monotonic kinetics, that can be typically characterized by the combination of two Haldane models. The optimal synthesis may present several singular arcs.
Dochain, Denis, Rapaport, Alain
core   +7 more sources

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami   +4 more
wiley   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi   +2 more
wiley   +1 more source

Improving Bioprocess Conditions for the Production of Prodigiosin Using a Marine Serratia rubidaea Strain

open access: yesMarine Drugs
The enormous potential attributed to prodigiosin regarding its applicability as a natural pigment and pharmaceutical agent justifies the development of sound bioprocesses for its production.
Ricardo F. S. Pereira   +1 more
doaj   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan   +9 more
wiley   +1 more source

Tissue engineering approaches to develop cultured meat from cells: A mini review

open access: yesCogent Food & Agriculture, 2017
Cultured meat production is an innovative and emerging process to produce animal meat in laboratories, using tissue-engineering techniques. This novel approach to produce meat involves in vitro culture of the animal muscle tissues rather than rearing ...
Muhammad Sajid Arshad   +5 more
doaj   +1 more source

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