Results 1 to 10 of about 1,355,379 (265)

Introduction of human m6Am methyltransferase PCIF1 facilitates the biosynthesis of terpenoids in Saccharomyces cerevisiae [PDF]

open access: yesMicrobial Cell Factories
Background The application of synthetic biology techniques has been recognized as an efficient alternative for the biosynthesis of high-value natural products, and various metabolic engineering strategies have been employed to develop microbial cell ...
Guoli Wang   +8 more
doaj   +2 more sources

Collagens - structure, function and biosynthesis. [PDF]

open access: yesAdvanced Drug Delivery Reviews, 2003
The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions.
Aigner, T, Gelse, K, Poschl, E
core   +2 more sources

Glutamate, Ornithine, Arginine, Proline, and Polyamine Metabolic Interactions: The Pathway Is Regulated at the Post-Transcriptional Level [PDF]

open access: yes, 2016
The metabolism of glutamate into ornithine, arginine, proline, and polyamines is a major network of nitrogen-metabolizing pathways in plants, which also produces intermediates like nitric oxide, and γ-aminobutyric acid (GABA) that play critical roles in ...
Boubker eBarchi   +7 more
core   +10 more sources

The Flavonoid Biosynthesis Network in Plants

open access: yesInternational Journal of Molecular Sciences, 2021
Flavonoids are an important class of secondary metabolites widely found in plants, contributing to plant growth and development and having prominent applications in food and medicine.
Weixin Liu   +6 more
semanticscholar   +1 more source

Increasing glycolysis by deletion of kcs1 and arg82 improved S-adenosyl-l-methionine production in Saccharomyces cerevisiae

open access: yesAMB Express, 2021
Reprogramming glycolysis for directing glycolytic metabolites to a specific metabolic pathway is expected to be useful for increasing microbial production of certain metabolites, such as amino acids, lipids or considerable secondary metabolites.
Hailong Chen   +7 more
doaj   +1 more source

Salicylic Acid: Biosynthesis and Signaling.

open access: yesAnnual Review of Plant Biology, 2021
Salicylic acid (SA) is an essential plant defense hormone that promotes immunity against biotrophic and semibiotrophic pathogens. It plays crucial roles in basal defense and the amplification of local immune responses, as well as the establishment of ...
Yujun Peng   +3 more
semanticscholar   +1 more source

Biocatalytic routes to stereo-divergent iridoids

open access: yesNature Communications, 2022
Iridoid compounds are an important class of natural products. Here, the authors report on the discovery and engineering of nepetalactol-related short chain reductases and their application for the biosynthesis of nepetalactol or nepetalactone ...
Néstor J. Hernández Lozada   +12 more
doaj   +1 more source

Directed Biosynthesis of New to Nature Alkaloids in a Heterologous Nicotiana benthamiana Expression Host

open access: yesFrontiers in Plant Science, 2022
Plants produce a wide variety of pharmacologically active molecules classified as natural products. Derivatization of these natural products can modulate or improve the bioactivity of the parent compound. Unfortunately, chemical derivatization of natural
Marianna Boccia   +4 more
doaj   +1 more source

Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner

open access: yesCell Death and Disease, 2021
Increased reactive oxygen species levels in the mitochondrial matrix can induce Parkin-dependent mitophagy, which selectively degrades dysfunctional mitochondria via the autolysosome pathway. Phosphorylated mitofusin-2 (MFN2), a receptor of parkin RBR E3
Cheng Zhang   +11 more
doaj   +1 more source

SspABCD-SspFGH Constitutes a New Type of DNA Phosphorothioate-Based Bacterial Defense System

open access: yesmBio, 2021
We recently found that SspABCD, catalyzing single-stranded (ss) DNA phosphorothioate (PT) modification, coupled with SspE provides protection against phage infection.
Shiwei Wang   +12 more
doaj   +1 more source

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