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The Flavonoid Biosynthesis Network in Plants
International Journal of Molecular Sciences, 2021 Flavonoids are an important class of secondary metabolites widely found in plants, contributing to plant growth and development and having prominent applications in food and medicine.
Weixin Liu +6 more
semanticscholar +1 more source
Salicylic Acid: Biosynthesis and Signaling.
Annual Review of Plant Biology, 2021 Salicylic acid (SA) is an essential plant defense hormone that promotes immunity against biotrophic and semibiotrophic pathogens. It plays crucial roles in basal defense and the amplification of local immune responses, as well as the establishment of ...
Yujun Peng +3 more
semanticscholar +1 more source
MYB-Mediated Regulation of Anthocyanin Biosynthesis
International Journal of Molecular Sciences, 2021 Anthocyanins are natural water-soluble pigments that are important in plants because they endow a variety of colors to vegetative tissues and reproductive plant organs, mainly ranging from red to purple and blue. The colors regulated by anthocyanins give
Huiling Yan +8 more
semanticscholar +1 more source
AMB Express, 2021 Reprogramming glycolysis for directing glycolytic metabolites to a specific metabolic pathway is expected to be useful for increasing microbial production of certain metabolites, such as amino acids, lipids or considerable secondary metabolites.
Hailong Chen +7 more
doaj +1 more source
Frontiers in Plant Science, 2022 Plants produce a wide variety of pharmacologically active molecules classified as natural products. Derivatization of these natural products can modulate or improve the bioactivity of the parent compound. Unfortunately, chemical derivatization of natural
Marianna Boccia +4 more
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Biocatalytic routes to stereo-divergent iridoids
Nature Communications, 2022 Iridoid compounds are an important class of natural products. Here, the authors report on the discovery and engineering of nepetalactol-related short chain reductases and their application for the biosynthesis of nepetalactol or nepetalactone ...
Néstor J. Hernández Lozada +12 more
doaj +1 more source
Cell Death and Disease, 2021 Increased reactive oxygen species levels in the mitochondrial matrix can induce Parkin-dependent mitophagy, which selectively degrades dysfunctional mitochondria via the autolysosome pathway. Phosphorylated mitofusin-2 (MFN2), a receptor of parkin RBR E3
Cheng Zhang +11 more
doaj +1 more source
Frontiers in Microbiology, 2020 Microbial natural products have been a cornerstone of the pharmaceutical industry, but the supply of novel bioactive secondary metabolites has diminished due to extensive exploration of the most easily accessible sources, namely terrestrial Streptomyces ...
Soheila Matroodi +6 more
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SspABCD-SspFGH Constitutes a New Type of DNA Phosphorothioate-Based Bacterial Defense System
mBio, 2021 We recently found that SspABCD, catalyzing single-stranded (ss) DNA phosphorothioate (PT) modification, coupled with SspE provides protection against phage infection.
Shiwei Wang +12 more
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Microbial Cell Factories, 2022 Background Saccharomyces cerevisiae is often used as a cell factory for the production of S-adenosyl-l-methionine (SAM) for diverse pharmaceutical applications. However, SAM production by S.
Hailong Chen +7 more
doaj +1 more source