Results 11 to 20 of about 681,288 (296)
The biosynthesis of the cannabinoids [PDF]
Abstract Cannabis has been integral to Eurasian civilization for millennia, but a century of prohibition has limited investigation. With spreading legalization, science is pivoting to study the pharmacopeia of the cannabinoids, and a thorough understanding of their biosynthesis is required to engineer strains with specific ...
M. Nazir Tahir +3 more
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AbstractStrychnine is a natural product that, through isolation, structural elucidation and synthetic efforts, shaped the field of organic chemistry. Currently, strychnine is used as a pesticide to control rodents1because of its potent neurotoxicity2,3.
Benke Hong +8 more
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The biosynthesis of pyoverdines [PDF]
Pyoverdines are fluorescent siderophores of pseudomonads that play important roles for growth under iron-limiting conditions. The production of pyoverdines by fluorescent pseudomonads permits their colonization of hosts ranging from humans to plants.
Michael T. Ringel, Thomas Brüser
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The biosynthesis of glucosamine [PDF]
Abstract A partially purified enzyme has been prepared from Neurospora crassa which catalyzes the formation of glucosamine phosphate from hexose-6-phosphate and glutamine. The glucosamine phosphate was identified by colour reactions, by dephosphorylation and paper chromatography and by its behaviour towards an acetylating system.
Leloir, Luis Federico +1 more
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Streptovaricin C is an antibiotic containing a methylenedioxy bridge (MDB) moiety essential for its activity. Here, the authors show that a P450 monooxygenase StvP2 catalyses MDB formation, report its crystal structure in complex with the substrate, and ...
Guo Sun +9 more
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Revolution of vitamin E production by starting from microbial fermented farnesene to isophytol
Vitamin E is one of the most widely used vitamins. In the classical commercial synthesis of vitamin E (α-tocopherol), the chemical synthesis of isophytol is the key technical barrier.
Ziling Ye +12 more
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The biosynthesis of porphyrins [PDF]
This article is intended as a summary of some of the work which has been done, over the past ten years, on the biosynthesis of porphyrins. The treatment accorded to this subject should not be considered to be that of an exhaustive review article. It will consider only those papers which, in the author’s opinion, are most pertinent to the particular ...
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Biosynthesis of Sespendole [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Satoshi Omura +2 more
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The effects of estrogen on targeted cancer therapy drugs
Improving the efficacy of anticancer drugs is especially challenging. Estrogen is a sex hormone that not only promotes the development of female secondary sexual characteristics, but also supports many important physiological functions.
Ying Zhao +4 more
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Expression and gene regulatory network of SNHG1 in hepatocellular carcinoma
Background Small nucleolar RNA host gene 1 (SNHG1), a long noncoding RNA (lncRNA), is a transcript that negatively regulates tumour suppressor genes, such as p53. Abnormal SNHG1 expression is associated with cell proliferation and cancer.
Chaoran Zheng, Shicheng Yu
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