Results 21 to 30 of about 681,288 (296)

A Cysteine-Reloading Process Initiating the Biosynthesis of the Bicyclic Scaffold of Dithiolopyrrolones

open access: yesAntibiotics, 2023
Dithiolopyrrolone antibiotics are well known for their outstanding biological activities, and their biosynthesis has been studied vigorously. However, the biosynthesis mechanism of the characteristic bicyclic scaffold is still unknown after years of ...
Yan Chen   +4 more
doaj   +1 more source

Biosynthesis of Pectin [PDF]

open access: yesPlant Physiology, 2010
The plant cell wall is composed of polysaccharides and proteins. In addition, some cells have walls impregnated with lignin. In all cases, the polysaccharides constitute the major part of the wall.
Harholt, Jesper   +2 more
openaire   +4 more sources

Oxidation of unsaturated fatty acids by leaf tissue

open access: yesJournal of Lipid Research, 1964
Plant leaf systems have been incubated under various conditions with uniformly labeled oleic acid, and the breakdown products identified by gas–liquid chromatography.
C. Hitchcock, A.T. James
doaj   +1 more source

Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system

open access: yesNature Communications, 2021
Angustmycin A is a nucleoside antibiotic having anti-mycobacterial and cytokinin activities. Here, the authors report the whole pathway leading to angustmycin A biosynthesis in Streptomyces and achieve the heterologous production of angustmycin A in E ...
Le Yu   +8 more
doaj   +1 more source

Natural Products from Mangrove Actinomycetes

open access: yesMarine Drugs, 2014
Mangroves are woody plants located in tropical and subtropical intertidal coastal regions. The mangrove ecosystem is becoming a hot spot for natural product discovery and bioactivity survey.
Dong-Bo Xu   +4 more
doaj   +1 more source

Biosynthesis of Prostaglandins [PDF]

open access: yesAnnual Review of Nutrition, 1991
Highly purified cyclooxygenase from sheep vesicular glands is stimulated by the presence of protoporphyrin IX compounds. This stimulation may be due to the conversion of an apoenzyme to the holoenzyme, and full activity is achieved when half of the enzyme subunits (70,000 daltons) bind heme.
openaire   +3 more sources

Collagen Biosynthesis [PDF]

open access: yesEnvironmental Health Perspectives, 1984
Collagen is the major structural protein of the lung. At least five genetically distinct collagen types have been identified in lung tissue. However, the precise role of collagen in nonrespiratory lung function is not well understood, in part because of the difficulties inherent in studying lung collagen, regardless of the type of assay used.
Last, JA, Reiser, KM
openaire   +4 more sources

Effect of very low nicotine content cigarettes on smoking behavior in Chinese smokers with genotype-stratified nicotine metabolism rates

open access: yesFrontiers in Psychiatry
BackgroundSmoking is a major public health issue worldwide, particularly in China where it is linked to serious diseases like lung cancer and cardiovascular disease. The genetic basis of nicotine metabolism, which varies significantly between Chinese and
Wanwan Ma   +15 more
doaj   +1 more source

A new type of DNA phosphorothioation-based antiviral system in archaea

open access: yesNature Communications, 2019
The prokaryote defence system Dnd relies on phosphorothioation (PT) of DNA backbone to distinguish between self and non-self DNA. Here, Xiong et al. describe a previously uncharacterized PT-based antiviral system that is independent of the canonical Dnd ...
Lei Xiong   +12 more
doaj   +1 more source

Puromycin A, B and C, cryptic nucleosides identified from Streptomyces alboniger NRRL B-1832 by PPtase-based activation

open access: yesSynthetic and Systems Biotechnology, 2018
Natural product discovery is pivot for drug development, however, this endeavor is often challenged by the wide inactivation or silence of natural products biosynthetic pathways.
Xiaoli Yan   +8 more
doaj   +1 more source

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