Results 21 to 30 of about 620,460 (320)

Biosynthesis of Sespendole [PDF]

open access: yesThe Journal of Antibiotics, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Satoshi Omura   +2 more
openaire   +4 more sources

Phenotypic continuum of NFU1‐related disorders

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2025-2035, December 2022., 2022
Abstract Bi‐allelic variants in Iron–Sulfur Cluster Scaffold (NFU1) have previously been associated with multiple mitochondrial dysfunctions syndrome 1 (MMDS1) characterized by early‐onset rapidly fatal leukoencephalopathy. We report 19 affected individuals from 10 independent families with ultra‐rare bi‐allelic NFU1 missense variants associated with a
Rauan Kaiyrzhanov   +45 more
wiley   +1 more source

Applications of machine Learning to improve the efficiency and range of microbial biosynthesis: a review of state-of-art techniques [PDF]

open access: yesarXiv, 2023
In the modern world, technology is at its peak. Different avenues in programming and technology have been explored for data analysis, automation, and robotics. Machine learning is key to optimize data analysis, make accurate predictions, and hasten/improve existing functions.
arxiv  

Investigation of In Vitro Apocarotenoid Expression in Perianth of Saffron (Crocus sativus L.) Under Different Soil EC [PDF]

open access: yes, 2023
Crocus sativus is a triploid sterile plant with red stigmas belonging to the family of Iridaceae, and sub-family Crocoideae. Crocin, picrocrocin, and safranal are three major carotenoid derivatives that are responsible for the color, taste, and specific aroma of Crocus.
arxiv   +1 more source

Biosynthesis of Pectin [PDF]

open access: yesPlant Physiology, 2010
The plant cell wall is composed of polysaccharides and proteins. In addition, some cells have walls impregnated with lignin. In all cases, the polysaccharides constitute the major part of the wall.
Harholt, Jesper   +2 more
openaire   +4 more sources

Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system

open access: yesNature Communications, 2021
Angustmycin A is a nucleoside antibiotic having anti-mycobacterial and cytokinin activities. Here, the authors report the whole pathway leading to angustmycin A biosynthesis in Streptomyces and achieve the heterologous production of angustmycin A in E ...
Le Yu   +8 more
doaj   +1 more source

Anomalous thermal fluctuation distribution sustains proto-metabolic cycles and biomolecule synthesis [PDF]

open access: yesPhysical Chemistry Chemical Physics 2019, 2019
An environment far from equilibrium is thought to be a necessary condition for the origin and persistence of life. In this context we report open-flow simulations of a non-enzymic proto-metabolic system, in which hydrogen peroxide acts both as oxidant and driver of thermochemical cycling. We find that a Gaussian perturbed input produces a non-Boltzmann
arxiv   +1 more source

A new type of DNA phosphorothioation-based antiviral system in archaea

open access: yesNature Communications, 2019
The prokaryote defence system Dnd relies on phosphorothioation (PT) of DNA backbone to distinguish between self and non-self DNA. Here, Xiong et al. describe a previously uncharacterized PT-based antiviral system that is independent of the canonical Dnd ...
Lei Xiong   +12 more
doaj   +1 more source

Puromycin A, B and C, cryptic nucleosides identified from Streptomyces alboniger NRRL B-1832 by PPtase-based activation

open access: yesSynthetic and Systems Biotechnology, 2018
Natural product discovery is pivot for drug development, however, this endeavor is often challenged by the wide inactivation or silence of natural products biosynthetic pathways.
Xiaoli Yan   +8 more
doaj   +1 more source

Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses [PDF]

open access: yesMol Cell Proteomics 12, 11 (2013) 3108-22, 2013
The molecular responses of macrophages to copper-based nanoparticles have been investigated via a combination of proteomic and biochemical approaches, using the RAW264.7 cell line as a model. Both metallic copper and copper oxide nanoparticles have been tested, with copper ion and zirconium oxide nanoparticles used as controls.
arxiv   +1 more source

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