Results 21 to 30 of about 1,261,328 (293)

A truncated lipoglycan from mycobacteria with altered immunological properties [PDF]

, 2010
Maintenance of cell-wall integrity in Mycobacterium tuberculosis is essential and is the target of several antitubercular drugs. For example, ethambutol targets arabinogalactan and lipoarabinomannan (LAM) biosynthesis through the inhibition of several ...
Alderwick, Luke J., Appelmelk, B. J., Besra, Gurdyal S, Bhatt, Apoorva, Birch, Helen, Eggeling, Lothar, Geurtsen, J, Maaskant, J, Nigou, Jerome, Singh, Albel   +9 more
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Oxidation of unsaturated fatty acids by leaf tissue

Journal of Lipid Research, 1964
Plant leaf systems have been incubated under various conditions with uniformly labeled oleic acid, and the breakdown products identified by gas–liquid chromatography.
C. Hitchcock, A.T. James
doaj   +1 more source

Diversity and biosynthetic potential of culturable microbes associated with toxic marine animals [PDF]

, 2013
Tetrodotoxin (TTX) is a neurotoxin that has been reported from taxonomically diverse organisms across 14 different phyla. The biogenic origin of tetrodotoxin is still disputed, however, TTX biosynthesis by host-associated bacteria has been reported.
Chau, Rocky, Kalaitzis, John, Neilan, Brett, Wood, Susanna A.   +3 more
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Structures and functions of mitochondrial ABC transporters [PDF]

, 2015
A small number of physiologically important ATP-binding cassette (ABC) transporters are found in mitochondria. Most are half transporters of the B group forming homodimers and their topology suggests they function as exporters.
Aller, Ardehali, Balk, Bayeva, Belinda Faust, Bernard, Chen, Chen, Chen, Chitra A. Shintre, Chloupková, Christensen, Csere, Dawson, Dudek, Elisabeth P. Carpenter, Feissner, Giegé, Gompf, Graf, Gutmann, Hendrik W. van Veen, Higgins, Higgins, Hofacker, Hogue, Hyde, Ichikawa, Janneke Balk, Jin, Kessler, Kispal, Kispal, Kiss, Kiss, Krishnamurthy, Krüssel, Kuhnke, Kushnir, Lee, Leighton, Li, Liesa, Lill, Lill, Mikolay, Mitsuhashi, Paterson, Pondarré, Pondarré, Poor, Qi, Rayapuram, San Francisco, Schaedler, Senbongi, Shintre, Shirihai, Srinivasan, Teschner, Theresia A. Schaedler, Tiranti, Tsuchida, Vasundara Srinivasan, Ward, Yamamoto, Young, Zhang   +67 more
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Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system

Nature Communications, 2021
Angustmycin A is a nucleoside antibiotic having anti-mycobacterial and cytokinin activities. Here, the authors report the whole pathway leading to angustmycin A biosynthesis in Streptomyces and achieve the heterologous production of angustmycin A in E ...
Le Yu, Wenting Zhou, Yixuan She, Hongmin Ma, You-Sheng Cai, Ming Jiang, Zixin Deng, Neil P. J. Price, Wenqing Chen   +8 more
doaj   +1 more source

Group V Phospholipase A2 Induces Leukotriene Biosynthesis in Human Neutrophils through the Activation of Group IVA Phospholipase A2 [PDF]

, 2002
We reported previously that exogenously added human group V phospholipase A2 (hVPLA2) could elicit leukotriene B4 (LTB4) biosynthesis in human neutrophils (Han, S. K., Kim, K. P., Koduri, R., Bittova, L., Munoz, N. M., Leff, A. R., Wilton, D. C., Gelb, M.
Cho, Wonhwa, Han, Sang Kyou, Kim, Kwang Pyo, Kim, Young Jun, Leff, Alan R., Munoz, Nilda M., Sano, Hiroyuki, Zhu, Xiangdong   +7 more
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Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature [PDF]

, 2009
A microarray analysis was performed to study the effect of varying combinations of water activity and temperature on the activation of aflatoxin biosynthesis genes in Aspergillus flavus grown on YES medium. Generally A.
Abdel-Hadi, Ahmed, Geisen, Rolf, Magan, Naresh, Schmidt-Heydt, Markus   +3 more
core   +1 more source

A seed-specific regulator of triterpene saponin biosynthesis in Medicago truncatula [PDF]

, 2020
Plants produce a vast array of defense compounds to protect themselves from pathogen attack or herbivore predation. Saponins are a specific class of defense compounds comprising bioactive glycosides with a steroidal or triterpenoid aglycone backbone. The
Arendt, Philipp, Bicalho, Keylla, Buitink, Julia, Calegario, Gabriela, Ceulemans, Evi, Goossens, Alain, Gryffroy, Lore, Lacchini, Elia, Mertens, Jan, Pollier, Jacob, Ribeiro, Bianca, Vanden Bossche, Robin   +11 more
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De novo formation of an aggregation pheromone precursor by an isoprenyl diphosphate synthase-related terpene synthase in the harlequin bug. [PDF]

, 2018
Insects use a diverse array of specialized terpene metabolites as pheromones in intraspecific interactions. In contrast to plants and microbes, which employ enzymes called terpene synthases (TPSs) to synthesize terpene metabolites, limited information ...
Ghosh, Saikat Kumar B, Gundersen-Rindal, Dawn E, Khrimian, Ashot, Kuhar, Thomas P, Köllner, Tobias G, Lancaster, Jason, Lehner, Bryan, Luck, Katrin, Marek, Paul E, Muchlinski, Andrew, Sparks, Michael E, Tholl, Dorothea, Tittiger, Claus, Tokuhisa, James G, Wallingford, Anna, Weber, Donald C, Young, Sharon, Zerbe, Philipp   +17 more
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Effect of very low nicotine content cigarettes on smoking behavior in Chinese smokers with genotype-stratified nicotine metabolism rates

Frontiers in Psychiatry
BackgroundSmoking is a major public health issue worldwide, particularly in China where it is linked to serious diseases like lung cancer and cardiovascular disease. The genetic basis of nicotine metabolism, which varies significantly between Chinese and
Wanwan Ma, Wanwan Ma, Yaning Fu, Yaning Fu, Huan Chen, Huan Chen, Hongjuan Wang, Hongjuan Wang, Shulei Han, Shulei Han, Yushan Tian, Yushan Tian, Hongwei Hou, Hongwei Hou, Qingyuan Hu, Qingyuan Hu   +15 more
doaj   +1 more source