Results 21 to 30 of about 1,068,298 (347)
Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae
Ergosterol is an essential component of fungal cell membranes that determines the fluidity, permeability and activity of membrane-associated proteins.
Tania Jordá, S. Puig
semanticscholar +1 more source
Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis.
The gastrointestinal (GI) tract contains much of the body's serotonin (5-hydroxytryptamine, 5-HT), but mechanisms controlling the metabolism of gut-derived 5-HT remain unclear.
J. Yano +9 more
semanticscholar +1 more source
Expression and gene regulatory network of SNHG1 in hepatocellular carcinoma
Background Small nucleolar RNA host gene 1 (SNHG1), a long noncoding RNA (lncRNA), is a transcript that negatively regulates tumour suppressor genes, such as p53. Abnormal SNHG1 expression is associated with cell proliferation and cancer.
Chaoran Zheng, Shicheng Yu
doaj +1 more source
Revolution of vitamin E production by starting from microbial fermented farnesene to isophytol
Vitamin E is one of the most widely used vitamins. In the classical commercial synthesis of vitamin E (α-tocopherol), the chemical synthesis of isophytol is the key technical barrier.
Ziling Ye +12 more
doaj +1 more source
Collagen is the major structural protein of the lung. At least five genetically distinct collagen types have been identified in lung tissue. However, the precise role of collagen in nonrespiratory lung function is not well understood, in part because of the difficulties inherent in studying lung collagen, regardless of the type of assay used.
Last, JA, Reiser, KM
openaire +4 more sources
The effects of estrogen on targeted cancer therapy drugs
Improving the efficacy of anticancer drugs is especially challenging. Estrogen is a sex hormone that not only promotes the development of female secondary sexual characteristics, but also supports many important physiological functions.
Ying Zhao +4 more
doaj +1 more source
Histidine (His) is one of the standard amino acids in proteins, and plays a critical role in plant growth and development. The chemical properties of the imidazole side group allow His to participate in acid-base catalysis, and in the co-ordination of metal ions.
openaire +2 more sources
The Taxus genome provides insights into paclitaxel biosynthesis
The ancient gymnosperm genus Taxus is the exclusive source of the anticancer drug paclitaxel, yet no reference genome sequences are available for comprehensively elucidating the paclitaxel biosynthesis pathway. We have completed a chromosome-level genome
Xingyao Xiong +18 more
semanticscholar +1 more source
Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system
Angustmycin A is a nucleoside antibiotic having anti-mycobacterial and cytokinin activities. Here, the authors report the whole pathway leading to angustmycin A biosynthesis in Streptomyces and achieve the heterologous production of angustmycin A in E ...
Le Yu +8 more
doaj +1 more source
Collagens--structure, function, and biosynthesis.
The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions.
Kolja Gelse, E. Pöschl, Thomas Aigner
semanticscholar +1 more source

