Results 1 to 10 of about 4,842 (50)

Repression of ZCT1, ZCT2 and ZCT3 affects expression of terpenoid indole alkaloid biosynthetic and regulatory genes [PDF]

open access: yesPeerJ, 2021
Terpenoid indole alkaloids (TIAs) include several valuable pharmaceuticals. As Catharanthus roseus remains the primary source of these TIA pharmaceuticals, several research groups have devoted substantial efforts to increase production of these compounds
Chun Yao Li, Susan I. Gibson
doaj   +2 more sources

Genome mining as a biotechnological tool for the discovery of novel biosynthetic genes in lichens

open access: yesFrontiers in Fungal Biology, 2022
Natural products (NPs) and their derivatives are a major contributor to modern medicine. Historically, microorganisms such as bacteria and fungi have been instrumental in generating drugs and lead compounds because of the ease of culturing and ...
Garima Singh   +8 more
doaj   +1 more source

Isolation and characterization of culturable actinobacteria associated with Polytrichum strictum (Galindez Island, the maritime Antarctic)

open access: yesУкраїнський антарктичний журнал, 2021
The main objective of the study is the evaluation of the diversity of actinobacteria associated with Polytrichum strictum — dominant species of widespread Antarctic Тall moss turf subformation and their characteristics as the producers of biologically ...
O. Gromyko   +6 more
doaj   +1 more source

Diversity of Bacterial Biosynthetic Genes in Maritime Antarctica

open access: yesMicroorganisms, 2020
Bacterial natural products (NPs) are still a major source of new drug leads. Polyketides (PKs) and non-ribosomal peptides (NRP) are two pharmaceutically important families of NPs and recent studies have revealed Antarctica to harbor endemic polyketide ...
Adriana Rego   +6 more
doaj   +1 more source

Anthocyanin Accumulation and Differential Expression of the Biosynthetic Genes Result in a Discrepancy in the Red Color of Herbaceous Peony (Paeonia lactiflora Pall.) Flowers

open access: yesHorticulturae, 2022
Herbaceous peony (Paeonia lactiflora Pall.) is an ornamental plant with huge potential in the international flower market. Similar to the flowers of most other ornamental plants, the top sellers of P.
Yanqing Wu   +3 more
doaj   +1 more source

Comparative transcriptome and flavonoids components analysis reveal the structural genes responsible for the yellow seed coat color of Brassica rapa L. [PDF]

open access: yesPeerJ, 2021
Background Seed coat color is an important horticultural trait in Brassica crops, which is divided into two categories: brown/black and yellow. Seeds with yellow seed coat color have higher oil quality, higher protein content and lower fiber content ...
Yanjing Ren   +4 more
doaj   +2 more sources

Long-Read Metagenomics of Marine Microbes Reveals Diversely Expressed Secondary Metabolites

open access: yesMicrobiology Spectrum, 2023
Microbial secondary metabolites play crucial roles in microbial competition, communication, resource acquisition, antibiotic production, and a variety of other biotechnological processes.
Ranran Huang   +5 more
doaj   +1 more source

Comparative genomics and transcriptomics analyses provide insights into the high yield and regulatory mechanism of Norvancomycin biosynthesis in Amycolatopsis orientalis NCPC 2-48

open access: yesMicrobial Cell Factories, 2021
Background Norvancomycin has been widely used in clinic to treat against MRSA (Methicillin-resistant Staphylococcus aureus) and MRSE (Methicillin-resistant Staphylococcus epidermidis) infections in China.
Xingxing Li   +9 more
doaj   +1 more source

Production of Potent Antimicrobial Compounds from Streptomyces cyaneofuscatus Associated with Fresh Water Sediment

open access: yesFrontiers in Microbiology, 2017
The genus Streptomyces under phylum actinobacteria has been recognized as a prolific source for the production of bioactive secondary metabolites. An actinobacterial strain designated as DST103 isolated from a wetland fresh water sediment of Tamdil Lake,
Zothanpuia   +6 more
doaj   +1 more source

Identification of target genes of the bZIP transcription factor OsTGAP1, whose overexpression causes elicitor-induced hyperaccumulation of diterpenoid phytoalexins in rice cells. [PDF]

open access: yesPLoS ONE, 2014
Phytoalexins are specialised antimicrobial metabolites that are produced by plants in response to pathogen attack. Momilactones and phytocassanes are the major diterpenoid phytoalexins in rice and are synthesised from geranylgeranyl diphosphate, which is
Koji Miyamoto   +8 more
doaj   +1 more source

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