Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin +15 more
wiley +1 more source
Genome-wide identification and comparative analysis of strigolactone biosynthetic genes in major solanaceous crops. [PDF]
Guo R +14 more
europepmc +1 more source
Soil bacteria from Muna Island, Southeast Sulawesi, Indonesia: Antibacterial and antibiofilm activities, and the presence of antibiotic-biosynthetic genes [PDF]
Egiyanti Nur Widhia Hening +5 more
openalex +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Bioproduction of raspberry ketone using <i>Phyllostachys</i> bamboo cells expressing raspberry ketone biosynthetic genes. [PDF]
Koeduka T, Yoshida K, Nomura T.
europepmc +1 more source
GLIS3 regulates transcription of thyroid hormone biosynthetic genes in coordination with other thyroid transcription factors. [PDF]
Kang HS +4 more
europepmc +1 more source
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li +11 more
wiley +1 more source
Delonix regia pollen extract enhances growth and bioactive compound production in Coriandrum sativum by upregulating key biosynthetic genes. [PDF]
Bassiouni EM +3 more
europepmc +1 more source
Cyclodextrins Increase Triterpene Production in Solanum lycopersicum Cell Cultures by Activating Biosynthetic Genes. [PDF]
Sabater-Jara AB +3 more
europepmc +1 more source

