DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
Advanced Materials, EarlyView.DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding +5 more
wiley +1 more source
Biotin: From Nutrition to Therapeutics.
Journal of NutriLife, 2017 Although frank symptomatic biotin deficiency is rare, some evidence suggests that marginal biotin deficiency occurs spontaneously in a substantial proportion of women during normal human pregnancy and might confer an increased risk of birth defects ...
D. Mock
semanticscholar +1 more source
Biotinidase Deficiency: Prevalence, Impact And Management Strategies
Pediatric Health, Medicine and Therapeutics, 2020 Ebru Canda, Sema Kalkan Uçar, Mahmut Çoker Department of Pediatrics, Faculty of Medicine, Ege University, Izmir, TurkeyCorrespondence: Ebru CandaDepartment of Pediatrics, Faculty of Medicine, Ege University, Izmir 35040, TurkeyTel + 90 232 ...
Canda E, Kalkan Uçar S, Çoker M
doaj
Nanophotonic waveguide enhanced Raman spectroscopy of biological submonolayers [PDF]
arXiv, 2016 Characterizing a monolayer of biological molecules has been a major challenge. We demonstrate nanophotonic wave-guide enhanced Raman spectroscopy (NWERS) of monolayers in the near-infrared region, enabling real-time measurements of the hybridization of DNA strands and the density of sub-monolayers of biotin-streptavidin complex immobilized on top of a ...
arxiv
Polyethylene imine-based receptor immobilization for label free bioassays [PDF]
, 2013 Polyethylene imine (PEI) based immobilization of antibodies is described and the concept is proved on the label free assay of C-Reactive Protein (CRP).
A. Hainard +35 more
core +1 more source
De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties
Advanced Materials, EarlyView.NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang +25 more
wiley +1 more source
LSR/angulin-1 is a tricellular tight junction protein involved in blood-brain barrier formation. [PDF]
, 2015 The blood-brain barrier (BBB) is a term used to describe the unique properties of central nervous system (CNS) blood vessels. One important BBB property is the formation of a paracellular barrier made by tight junctions (TJs) between CNS endothelial ...
Arnold, Thomas D +10 more
core +2 more sources
Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance
Advanced Materials, EarlyView.This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee +14 more
wiley +1 more source
Biotin Treatment Mimicking Graves' Disease.
New England Journal of Medicine, 2016 In six children, biotin produced changes in thyroid-function tests that mimic those seen in Graves' disease.
S. Kummer, D. Hermsen, F. Distelmaier
semanticscholar +1 more source
Insights Into the Carboxyltransferase Reaction of Pyruvate Carboxylase From the Structures of Bound Product and Intermediate Analogs [PDF]
, 2013 Pyruvate carboxylase (PC) is a biotin-dependent enzyme that catalyzes the MgATP- and bicarbonate-dependent carboxylation of pyruvate to oxaloacetate, an important anaplerotic reaction in central metabolism.
Lietzan, Adam D., Maurice, Martin St.
core +2 more sources