Results 71 to 80 of about 467,470 (351)

Insight into the Carboxyl Transferase Domain Mechanism of Pyruvate Carboxylase from \u3cem\u3eRhizobium etli\u3c/em\u3e [PDF]

, 2009
The effects of mutations in the active site of the carboxyl transferase domain of Rhizobium etli pyruvate carboxylase have been determined for the forward reaction to form oxaloacetate, the reverse reaction to form MgATP, the oxamate-induced ...
Attwood, Paul V, Cleland, W Wallace, Jitrapakdee, Sarawut, Maurice, Martin St., Wallace, John C., Zeczycki, Tonya N.   +5 more
core   +1 more source

Structural divergence of paralogous S components from ECF-type ABC transporters [PDF]

, 2012
Energy coupling factor (ECF) proteins are ATP-binding cassette transporters involved in the import of micronutrients in prokaryotes. They consist of two nucleotide-binding subunits and the integral membrane subunit EcfT, which together form the ECF ...
Beek, Josy ter,, Berntsson, Ronnie P.-A.,, Duurkens, Ria H.,, Majsnerowska, Maria,, Poolman, Bert,, Puri, Pranav,, Slotboom, Dirk-Jan,   +6 more
core   +4 more sources

Biological Precursors of Biotin and/or Biotin L-Sulfoxide

Experimental Biology and Medicine, 1955
SummaryPimelic and azelaic acids were found to be precursors of biotin L-sulfoxide in the growth of Aspergillus niger. Shorter chain dicarboxylic acids as well as suberic and se-bacic acids are inactive. A number of other miscellaneous compounds including oleic acid, Tween 80, and certain “traumatic acids, v with structural or functional relationships ...
L D, WRIGHT, E L, CRESSON, C A, DRISCOLL
openaire   +2 more sources

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

MicroRNA detection on microsensor arrays by SPR imaging measurements with enzymatic signal enhancement. [PDF]

, 2019
We investigated sequence-specific and simultaneous microRNA (miRNA) detections by surface plasmon resonance (SPR) imaging measurements on SPR chips possessing an Au spot array modified with probe DNAs based on a miRNA-detection-selective SPR signal ...
Aoki, Hiroshi, Corn, Robert M, Matthews, Brandon   +2 more
core  

Chemoenzymatic Probes for Detecting and Imaging Fucose-α(1-2)-galactose Glycan Biomarkers [PDF]

, 2012
The disaccharide motif fucose-α(1-2)-galactose (Fucα(1-2)Gal) is involved in many important physiological processes, such as learning and memory, inflammation, asthma, and tumorigenesis.
Becker D. J., Blixt O., Blixt O., Chang C.-F., Chang W.-W., Chithra Krishnamurthy, Clark P. M., David F. Smith, Delves P. J., Hanson S. R., Jean-Luc Chaubard, Khidekel N., Kim Y., Laughlin S. T., Lee J. S., Linda C. Hsieh-Wilson, Manimala J. C., Manimala J. C., Miyake M., Murrey H. E., Murrey H. E., Peracaula R., Pohle W., Rexach J. E., Schröder F. H., Tanaka Y., Tiunova A. A., Wen Yi, Yi W., Zhang S., Zheng T.   +30 more
core   +3 more sources

Relationship of Biotin Deposition in Turkey Eggs to Dietary Biotin and Biotin-Binding Proteins

Poultry Science, 1987
The biotin and biotin-binding protein contents of egg yolk, egg albumen, and hen plasma were determined on eight groups of four turkey hens each that had been fed diets ranging from less than 10 to 3,475 micrograms available biotin per kilogram. Biotin deposition in the yolk was strongly dependent upon available dietary biotin below 100 micrograms/kg ...
H B, White, C C, Whitehead, J, Armstrong
openaire   +2 more sources

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Molecular cytotaxonomy of primates by chromosomal in situ suppression hybridization [PDF]

, 1990
A new strategy for analyzing chromosomal evolution in primates is presented using chromosomal in situ suppression (CISS) hybridization. Biotin-labeled DNA libraries from flow-sorted human chromosomes are hybridized to chromosome preparations of ...
Anna Jauch, Bickmore, Cremer, Cremer, de Grouchy, Dutrillaux, Holmquist, Johannes Wienberg, Lalley, Lichter, Lichter, Lichter, O'Brien, Ohno, Pinkel, Roscoe Stanyon, Seuánez, Stanyon, Thomas Cremer, Van Dilla, Weber, Wienberg, Yunis   +22 more
core   +1 more source

Wafer‐Scale Integration of α‐quartz Thin Films toward Super High Frequency Piezoelectric bioNEMS for Chikungunya Virus Detection

Advanced Functional Materials, EarlyView.
Epitaxial piezoelectric α‐quartz/Si BioNEMS sensors, made using soft chemistry, effectively detect the Chikungunya virus. They have a mass sensitivity of 205 pg Hz−1 in liquid and can detect the virus at a limit of 9 ng mL−1. This development enables high‐frequency mass devices for point‐of‐care testing in healthcare and other electronic applications ...
Raissa Rathar, Sijie Ding, David Sanchez‐Fuentes, Claire Jolly, Charlotte André‐Arpin, Rudy Desgarceaux, Nicolas Guillaume, Gustavo Ardila, Ricardo Garcia‐Bermejo, Jaume Gazquez, Sergi Plana‐Ruiz, Laura Picas, Adrian Carretero‐Genevrier   +12 more
wiley   +1 more source