Results 251 to 260 of about 117,043 (340)

Innovative pharmacotherapy for hepatic metabolic and chronic inflammatory diseases in China

British Journal of Pharmacology, EarlyView.
Abstract Liver disease constitutes a significant global health concern, particularly in China where it has distinctive characteristics. China grapples with a staggering 300 million cases, predominantly due to hepatitis B and metabolic non‐alcoholic fatty liver disease. Additionally, hepatocellular carcinoma has become a prevalent which is a lethal type
Feng Zhang, Jiaming Ju, Hongtao Diao, Jinglun Song, Yu bian, Baofeng Yang   +5 more
wiley   +1 more source

The transformation pathways and optimization of conditions for preparation minor ginsenosides from Panax notoginseng root by the fungus Aspergillus tubingensis. [PDF]

PLoS One
Li FX, Lin DM, Yang J, Cui XM, Yang XY.
europepmc   +1 more source

Studies on the biotransformation and anti-ulcer effects of 2-(nicotinoylaminoethanesulfonylamino)pyridine.

, 1985
Hisashi Tanaka, Shun‐Ichi Naito
openalex   +2 more sources

Biotransformation of the Fluoroquinolone Antibiotic, Levofloxacin, by the Free and Immobilized Secretome of Coriolopsis gallica. [PDF]

J Fungi (Basel)
Staita K, Khmaissa M, Akrout I, Greff S, Ghariani B, Turbé-Doan A, Lambert J, Lomascolo A, Albert Q, Faulds CB, Sciara G, Zouari-Mechichi H, Record E, Mechichi T.   +13 more
europepmc   +1 more source

Studies on Absorption, Biotransformation and Excretion of Drug. VIII. Metabolic Fate of a New Analgesic and Anti-inflammatory Agent, 2-Oxo-3-[4-(1-oxo-2-isoindolinyl) phenyl]-butanamide (OIB) in Rats

, 1982
KAZUO KIGASAWA, M. HIIRAGI, Kouichi Maruyama, Makoto Tanaka, YASUTUGU OHSAWA, Toshihiro Hayashi   +5 more
openalex   +2 more sources

An adamantane‐based ligand as a novel chemical tool for thermosensory TRPM8 channel therapeutic modulation

The FEBS Journal, EarlyView.
Transient receptor potential cation channel subfamily M member 8 (TRPM8) is a cationic thermosensory channel crucial for cold sensation and menthol response. TRPM8 dysfunction leads to sensory symptoms such as cold allodynia. Targeting TRPM8 is important for treating diseases like peripheral neuropathies and cancer.
Angela Lamberti, Silvio Aprile, David Cabañero, Fabio Travagin, Laura Butron, Gregorio Fernández‐Ballester, Gian Cesare Tron, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel, Ubaldina Galli   +9 more
wiley   +1 more source

GutBugDB: a web resource to predict the human gut microbiome-mediated biotransformation of biotic and xenobiotic molecules. [PDF]

Gut Microbiome (Camb)
Longwani U, Sharma AK, Malwe AS, Jaiswal SK, Sharma VK.   +4 more
europepmc   +1 more source

Unraveling the functional dynamics of Caenorhabditis elegans stress‐responsive omega class GST‐44

The FEBS Journal, EarlyView.
Omega‐class glutathione S‐transferases (GSTs) are integral to redox regulation and cellular stress responses. This study characterized GST‐44 in Caenorhabditis elegans, revealing its predominant expression in the intestine and excretory H‐cell, with significant upregulation under various stress conditions.
Charlotte Sophia Kaiser, Milena Lubisch, Emma Schröder, Luka Ressmann, Marie Nicolaus, Dustin Leusder, Sven Moyzio, Robert Peuss, Antonio Miranda‐Vizuete, Eva Liebau   +9 more
wiley   +1 more source

Valorization of Oil Cakes in Two-Pot Lactone Biosynthesis Process. [PDF]

Foods
Małajowicz J, Fabiszewska A, Zieniuk B, Bryś J, Kozłowska M, Marciniak-Lukasiak K.   +5 more
europepmc   +1 more source

Characterization of a GH43 Bifunctional Glycosidase from Endophytic <i>Chaetomium globosum</i> and Its Potential Application in the Biotransformation of Ginsenosides. [PDF]

BioTech (Basel)
Lu Y, Jiang Q, Dong Y, Ji R, Xiao Y, Zhu D, Gao B.   +6 more
europepmc   +1 more source