Patents on Endophytic Fungi Related to Secondary Metabolites and Biotransformation Applications
Endophytic fungi are an important group of microorganisms and one of the least studied. They enhance their host’s resistance against abiotic stress, disease, insects, pathogens and mammalian herbivores by producing secondary metabolites with a wide ...
Daniel Torres-Mendoza +2 more
semanticscholar +1 more source
Alcohol dehydrogenases (ADHs) are best known for reducing ketones to chiral alcohols, but their oxidative potential is rarely exploited. Here, we show that selected ADHs catalyze newly discovered promiscuous transformations: the oxidative coupling of primary alcohols with amines or thiols, enabling the direct and efficient synthesis of a broad range of
Matteo Damian +4 more
wiley +2 more sources
Comparison in antioxidant and antitumor activities of pine polyphenols and its seven biotransformation extracts by fungi [PDF]
Microbial transformation can strengthen the antioxidant and antitumor activities of polyphenols. Polyphenols contents, antioxidant and antitumor activities of pine polyphenols and its biotransformation extracts by Aspergillus niger, Aspergillus oryzae ...
Hui Li, Zhenyu Wang
doaj +2 more sources
Biocatalytic preparation and absolute configuration of enantiomerically pure fungistatic anti-2-benzylindane derivatives. Study of the detoxification mechanism by Botrytis cinerea [PDF]
Enantiomerically pure 2-benzylindane derivatives were prepared using biocatalytic methods and their absolute configuration determined. (1R,2S)-2-Benzylindan-1-ol ((1R,2S)-2) and (S)-2-benzylindan-1-one ((S)-3) were produced by fermenting baker’s yeast.
Aleu +23 more
core +2 more sources
Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler +4 more
wiley +2 more sources
In this paper we describe the chemoenzymatic synthesis of enantiopure l-2-arylthiazol-4-yl alanines starting from their racemic N-acetyl derivatives; by combining the lipase-catalysed dynamic kinetic resolution of oxazol-5(4H)-ones with a chemical and an
Denisa Leonte +5 more
doaj +1 more source
Biotransformation of halogenated compounds by lyophilized cells of Rhodococcus erythropolis in a continuous solid-gas biofilter [PDF]
The irreversible hydrolysis of 1-chlorobutane to 1-butanol and HCl by lyophilized cells of Rhodococcus erythropolis NCIMB 13064, using a solid–gas biofilter, is described as a model reaction.
Erable, Benjamin +4 more
core +4 more sources
Recent Advances in Biotransformation of Saponins
Saponins are a class of glycosides whose aglycones can be either triterpenes or helical spirostanes. It is commonly recognized that these active ingredients are widely found in various kinds of advanced plants.
Yi He +9 more
semanticscholar +1 more source
Mycotoxins: Biotransformation and Bioavailability Assessment Using Caco-2 Cell Monolayer
The determination of mycotoxins content in food is not sufficient for the prediction of their potential in vivo cytotoxicity because it does not reflect their bioavailability and mutual interactions within complex matrices, which may significantly alter ...
Van Nguyen Tran, J. Viktorová, T. Ruml
semanticscholar +1 more source
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco +8 more
wiley +1 more source

