Impacts of in vivo and in vitro exposures to tamoxifen: comparative effects on human cells and marine organisms [PDF]
, 2019 Tamoxifen (TAM) is a first generation-SERM administered for hormone receptor-positive (HER+) breast cancer in both pre- and post-menopausal patients and may undergo metabolic activation in organisms that share similar receptors and thus face comparable ...
Abessa, D. M. S. +5 more
core +1 more source
New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites. [PDF]
, 2019 Synthetic cannabinoids (SCs) were initially developed as pharmacological tools to probe the endocannabinoid system and as novel pharmacotherapies, but are now highly abused.
Diao, Xingxing, Huestis, Marilyn A.
core +2 more sources
Arsenic biotransformation potential of six marine diatom species: effect of temperature and salinity
Scientific Reports, 2019 Temperature and salinity effects on marine diatom species growth has been studied extensively; however, their effect on arsenic (As) biotransformation has been imprecise.
Rimana Islam Papry +7 more
semanticscholar +1 more source
A Critical Review of Bioaccumulation and Biotransformation of Organic Chemicals in Birds [PDF]
, 2022 A literature review of bioaccumulation and biotransformation of organic chemicals in birds was undertaken, aiming to support scoping and prioritization of future research.
Deglin, Sandrine +9 more
core +1 more source
Environmental Science and Technology, 2019 Biotransformation of chemical contaminants is of importance in various natural and engineered systems. However, in complex microbial communities and with chemical contaminants at low concentrations, our current understanding of biotransformation at the ...
Stefan Achermann +4 more
semanticscholar +1 more source
The Phenion (R) Full-Thickness Skin Model for Percutaneous Absorption Testing [PDF]
, 2010 In recent years many efforts have been made to replace dermal toxicity testing of chemicals in the animal by in vitro assays. As a member of a German research consortium, we have previously contributed to the validation of an in vitro test protocol for ...
Ackermann, K. +4 more
core +1 more source
Biodiesel via in situ wet microalgae biotransformation: Zwitter-type ionic liquid supported extraction and transesterification [PDF]
, 2017 The production of biodiesel derived from microalgae is among the most forthcoming technologies that provide an ecologic alternative to fossil fuels.
Bauer, Gerald +4 more
core +2 more sources
Biodegradation and Biotransformation of Indole: Advances and Perspectives
Frontiers in Microbiology, 2018 Indole is long regarded as a typical N-heterocyclic aromatic pollutant in industrial and agricultural wastewater, and recently it has been identified as a versatile signaling molecule with wide environmental distributions. An exponentially growing number
Q. Ma, Xuwang Zhang, Y. Qu
semanticscholar +1 more source
Drug Metabolism And Disposition, 2019 For therapeutic proteins, the currently established standard development path generally does not foresee biotransformation studies by default because it is well known that the clearance of therapeutic proteins proceeds via degradation to small peptides ...
S. Schadt +10 more
semanticscholar +1 more source
Structural characterization of humic acids, extracted from sewage sludge during composting, by thermochemolysis–gas chromatography–mass spectrometry [PDF]
, 2006 Thermochemolysis coupled with gas chromatography and mass spectrometry were applied to determine the structure of humic acids (HA) extracted from a sewage sludge and straw mixture at different steps of composting.
Amblès, André +8 more
core +4 more sources