Results 21 to 30 of about 19,479 (186)

Biocatalytic hydroxylation of n-butane with in situ cofactor regeneration at low temperature and under normal pressure

Beilstein Journal of Organic Chemistry, 2012
The hydroxylation of n-alkanes, which proceeds in the presence of a P450-monooxygenase advantageously at temperatures significantly below room temperature, is described.
Svenja Staudt, Christina A. Müller, Jan Marienhagen, Christian Böing, Stefan Buchholz, Ulrich Schwaneberg, Harald Gröger   +6 more
doaj   +1 more source

Microbial Modifications of Androstane and Androstene Steroids by Penicillium vinaceum

Molecules, 2020
The biotransformation of steroid compounds is a promising, environmentally friendly route to new pharmaceuticals and hormones. One of the reaction types common in the metabolic fate of steroids is Baeyer-Villiger oxidation, which in the case of cyclic ...
Anna Panek, Paulina Łyczko, Alina Świzdor   +2 more
doaj   +1 more source

Recent Applications of Albumin as a Green and Versatile Catalyst in Organic Synthesis

Molecules
Today, biocatalytic methodologies are well established as useful tools in green organic synthesis, since biocatalysts are mild, sustainable, and environmentally friendly catalysts which provide selectivity to the reactions they catalyse.
Estefanía L. Borucki, Luis E. Iglesias
doaj   +1 more source

Δ1-Dehydrogenation and C20 Reduction of Cortisone and Hydrocortisone Catalyzed by Rhodococcus Strains

Molecules, 2020
Prednisone and prednisolone are steroids widely used as anti-inflammatory drugs. Development of the pharmaceutical industry is currently aimed at introducing biotechnological processes and replacing multiple-stage chemical syntheses.
Stefania Costa, Federico Zappaterra, Daniela Summa, Bruno Semeraro, Giancarlo Fantin   +4 more
doaj   +1 more source

New Hydroxylactones and Chloro-Hydroxylactones Obtained by Biotransformation of Bicyclic Halolactones and Their Antibacterial Activity

Molecules
The aim of this study was to obtain new halolactones with a gem-dimethyl group in the cyclohexane ring (at the C-3 or C-5 carbon) and a methyl group in the lactone ring and then subject them to biotransformations using filamentous fungi.
Małgorzata Grabarczyk, Anna Duda-Madej, Fedor Romanenko, Gabriela Maciejewska, Wanda Mączka, Agata Białońska, Katarzyna Wińska   +6 more
doaj   +1 more source

Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes

Frontiers in Pharmacology, 2015
The adverse effects to humans and environment of only few chemicals are well known. Absorption, distribution, metabolism and excretion (ADME) are the steps of pharmaco/toxicokinetics that determine the internal dose of chemicals to which the organism is ...
Hannu eRaunio
doaj   +1 more source

Glycosylation of 3-Hydroxyflavone, 3-Methoxyflavone, Quercetin and Baicalein in Fungal Cultures of the Genus Isaria

Molecules, 2018
Flavonoids are plant secondary metabolites with a broad spectrum of biological activities. In nature, they occur mainly in the form of glycosides, but their extraction is often difficult and expensive, as is chemical synthesis.
Monika Dymarska, Tomasz Janeczko, Edyta Kostrzewa-Susłow   +2 more
doaj   +1 more source

Resolution of Racemic Acids, Esters and Amines by Candida rugosa Lipase in Slightly Hydrated Organic Media

Food Technology and Biotechnology, 2004
Commercial crude lipase from Candida rugosa is widely used as a biocatalyst in the resolution of racemic mixtures and in organic synthesis in slightly hydrated organic solvents.
Andrés R. Alcántara, Pablo Domínguez de María, María Fernández, María José Hernaíz, José María Sánchez-Montero, José Vincente Sinisterra   +5 more
doaj  

Turning Mushy Lipids into Fruity Notes: Unlocking Lactone Biosynthesis Potential in Fat Industry Lipid Waste

Foods
Waste from the fat-processing industry represents a challenging stream due to its physicochemical properties and environmental impact. Valorization through recovery and reuse offers ecological, economic, and social benefits.
Jolanta Małajowicz, Katarzyna Wierzchowska, Karina Jasińska, Agata Fabiszewska   +3 more
doaj   +1 more source

Nucleotide sugar biosynthesis occurs in the glycosomes of procyclic and bloodstream form Trypanosoma brucei.

PLoS Neglected Tropical Diseases, 2021
In Trypanosoma brucei, there are fourteen enzymatic biotransformations that collectively convert glucose into five essential nucleotide sugars: UDP-Glc, UDP-Gal, UDP-GlcNAc, GDP-Man and GDP-Fuc. These biotransformations are catalyzed by thirteen discrete
Maria Lucia Sampaio Guther, Alan R Prescott, Sabine Kuettel, Michele Tinti, Michael A J Ferguson   +4 more
doaj   +1 more source