Results 31 to 40 of about 437,997 (293)

The functional impairment of different subtypes and occupational states in euthymic patients with bipolar disorder

BMC Psychiatry, 2021
Background The aim was to explore the associations between clinical symptoms, demographic variables, social and neurocognitive functioning in euthymic patients with bipolar disorder (BD) stratified by subgroups of DSM-IV BD (type I (BD-I) and type II (BD-
Xinyu Liu, Xiaojuan Ma, Wenchen Wang, Jian Zhang, Xia Sun, Xingguang Luo, Yong Zhang   +6 more
doaj   +1 more source

Differential efficacy of lithium and carbamazepine in the prophylaxis of bipolar disorder: Results of the MAP study [PDF]

, 2000
In a randomized clinical trial with an observation period of 2.5 years, the differential efficacy of lithium versus carbamazepine was compared in 171 bipolar patients (DSM-IV).
Waldemar Greil, Nikolaus Kleindienst, Greil, Waldemar, Kleindienst, Nikolaus   +3 more
core   +1 more source

Bipolar Disorder

The Lancet
The hallmark of bipolar disorder is hypomania or mania, and the predominant phase of illness is depression. Affecting approximately 40 million individuals worldwide, bipolar disorder is associated with a substantial psychosocial, medical, and financial burden and increased mortality from suicide and other causes.
Iyer V, Jain A, Mitra P.
europepmc   +3 more sources

Internet-based psychoeducation for bipolar disorder: a qualitative analysis of feasibility, acceptability and impact [PDF]

, 2012
<p>Background: In a recent exploratory randomised trial we found that a novel, internet-based psychoeducation programme for bipolar disorder (Beating Bipolar) was relatively easy to deliver and had a modest effect on psychological quality of life ...
Simpson, S.A., Daniel J Smith, Poole, R., Smith, D.J., Poole, Ria, Simpson, Sharon Anne, Sharon A Simpson, Ria Poole, Smith, Daniel J., Poole Ria, Simpson Sharon A, Smith Daniel J   +11 more
core   +2 more sources

Psychotropic drug repurposing for COVID-19: a systematic review

European Psychiatry, 2022
Introduction Recently, several antidepressants, mood stabilizers, and antipsychotics have been suggested to have favorable effects in the treatment of COVID-19.
U. Isayeva, G. Fico, S. Gomes-Da-Costa, M. Sagué Villavella, A. Gimenez, M. Manchia, A. Murru   +6 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Pilot study of circulating cell-free mitochondrial DNA in relation to brain structure in youth bipolar disorder

International Journal of Bipolar Disorders
Background Mitochondrial dysfunction is implicated in the neuropathology of bipolar disorder (BD). Higher circulating cell-free mitochondrial DNA (ccf-mtDNA), generally reflecting poorer mitochondrial health, has been associated with greater symptoms ...
Suyi Shao, Yi Zou, Kody G. Kennedy, Mikaela K. Dimick, Ana C. Andreazza, L. Trevor Young, Vanessa F. Goncalves, Bradley J. MacIntosh, Benjamin I. Goldstein   +8 more
doaj   +1 more source

Patient and physician perspectives of a smartphone application for depression: a qualitative study

BMC Psychiatry, 2021
Background Despite an increasing number of smartphone apps, such therapeutic tools have not yet consistently demonstrated their efficacy and many suffer from low retention rates. To ensure the development of efficient apps associated with high adherence,
Marie-Camille Patoz, Diego Hidalgo-Mazzei, Olivier Blanc, Norma Verdolini, Isabella Pacchiarotti, Andrea Murru, Laurent Zukerwar, Eduard Vieta, Pierre-Michel Llorca, Ludovic Samalin   +9 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source