Results 21 to 30 of about 2,355 (158)
Antioxidants, 2022 Our previous study showed that bisdemethoxycurcumin (BUR) exerts anti-inflammatory properties in lipopolysaccharide-induced intestinal injury, and studies have revealed that NOD-like receptor superfamily, pyrin domain containing 3 (NLRP3) inflammasome ...
Jingfei Zhang +7 more
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The impact of curcumin derived polyphenols on the structure and flexibility COVID-19 main protease binding pocket: a molecular dynamics simulation study [PDF]
PeerJ, 2021 The newly occurred SARS-CoV-2 caused a leading pandemic of coronavirus disease (COVID-19). Up to now it has infected more than one hundred sixty million and killed more than three million people according to 14 May 2021 World Health Organization report ...
Aweke Mulu +3 more
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Antioxidants, 2022 Curcuma longa constitutes an important source of secondary metabolites that have been associated with multiple health benefits. For instance, curcumin, demethoxycurcumin and bisdemethoxycurcumin, have been found to perform important biological activities,
María Isabel Quirós-Fallas +8 more
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Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids
BMC Cancer, 2004 Background Multidrug resistance (MDR) is a phenomenon that is often associated with decreased intracellular drug accumulation in patient's tumor cells resulting from enhanced drug efflux.
Buddhasukh Duang +2 more
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Molecules, 2021 The Curcuma longa plant is endowed with multiple traditional and therapeutic utilities and is here explored for its phytochemical constituents and cytotoxic potential.
Madhuri Grover +12 more
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Molecules, 2022 Bovine Serum Albumin (BSA) lipid hybrid nanoparticles are part of the new solutions to overcome low bioavailability of poor solubility drugs such as curcuminoids, which possess multiple biological advantages; however, they are counterbalanced by its ...
Andrea Mariela Araya-Sibaja +5 more
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Toxins, 2021 Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen of nosocomial infection, which is resistant to most antibiotics. Presently, anti-virulence therapy and anti-biofilm therapy are considered to be promising alternatives. In the current
Shu Wang, Ok-Hwa Kang, Dong-Yeul Kwon
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Novel Zn(II) Coordination Polymers Based on the Natural Molecule Bisdemethoxycurcumin [PDF]
Crystal Growth & Design, 2020 This article introduces a new family of coordination polymers (CPs) that contains a renewable curcumin derivative, the bisdemethoxycurcumin (BDMC), coordinated to Zn(II) centers. The reaction between BDMC and zinc acetate, performed under mild conditions in ethanol, provides a new 1D phase termed BDMCZn-1.
Laura Rodríguez-Cid +5 more
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Molecules, 2018 Deuterium oxide (D2O) has been reported to be active toward various in vitro cell lines in combination with phytochemicals. Our objective was to describe, for the first time, the effect of D2O on the proliferation of hepatic stellate cells (HSCs).
Phil Jun Lee +3 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 Curcuminoids are functional food additives, and the effect on gonadal hormone biosynthesis remains unclear. Gonads contain 3β-hydroxysteroid dehydrogenase isoforms, h3β-HSD2 (humans) and r3β-HSD1 (rats), which catalyse pregnenolone into progesterone. The
Xinyi Qiao +9 more
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