Exploring the production of high-value compounds in plant Catharanthus roseus hairy roots and yeast Yarrowia lipolytica [PDF]
, 2017 This dissertation focuses on studying the production of two categories of high-value compounds in bio organisms. The first group is terpenoid indole alkaloids (TIAs) in plant Catharanthus roseus, and the second group is wax esters, one of fatty acid ...
Zhao, Le
core +3 more sources
Calmodulin in Complex with Proteins and Small Molecule Ligands: Operating with the Element of Surprise. Implications for Structure-Based Drug Design [PDF]
, 2009 Calmodulin plays a role in several life processes, its flexibility allows binding of a number of different ligands from small molecules to amphiphilic peptide helices and proteins. Through the diversity of its functions, it is quite difficult to find new
Keserű, György Miklós +2 more
core
The Chemistry of Grandifoline, a Bisindole Alkaloid
, 1979 Department of Pure Chemistry, University College of Science, 92, Acharya P. C.
openaire +1 more source
MOLECULAR DOCKING OF HYRTIMOMINE A-K FROM MARINE SPONGE HYRTIOS SPP. AS ANTICANCER TARGET OF PHOSPHOINOSITIDE-DEPENDENT KINASE 1 [PDF]
, 2019 Objective: The hyrtimomine A-K class of indole-based compounds extracted from Hyrtios spp. of sponges from the sea has not been studied for their anticancer properties.
RAMA ADIGA
core +1 more source
Synthesis of 3,6-Bis(5’-bromo-3’-indolyl)-1,4-dimethypiperazine-2,5-dione [PDF]
, 2009 The one-pot synthesis of 3,6-bis(5’-bromo-3’-indolyl)-1,4-dimethylpiperazine- 2,5-dione is reported. Sarcosine anhydride is brominated and immediately reacted with 5-bromoindole to produce the product, which is characterized by 1H NMR, MS and ...
Crooke, Stephen N. +2 more
core +1 more source
Development and Praxis of Ph Drug Delivery System Contra Zika
, 2023 As the effects of global warming continue to spread throughout the world, another critical issue is slowly gaining attention in many urban tropical countries.
Rodriguez, Julissa
core +1 more source
Metabolomic characteristics of Catharanthus roseus plants in time and space [PDF]
, 2014 The thesis aims at combining metabolomics with other methods to investigate the regulation of the TIA biosynthesis and how this is connected with other pathways and the plant__s physiology and development.
Qifang, P.
core +1 more source
Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling. [PDF]
Oncotarget, 2017 Jie C +9 more
europepmc +1 more source
Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling. [PDF]
Oncotarget, 2016 Kong LM +8 more
europepmc +1 more source
NaHMDS/B(C<sub>6</sub>F<sub>5</sub>)<sub>3</sub>-promoted diastereoselective Friedel-Crafts alkylation of indoles/pyrroles with <i>N-tert</i>-butanesulfinylimines: towards the asymmetric synthesis of bisindole alkaloid Calcicamide B. [PDF]
RSC AdvZhang G +11 more
europepmc +1 more source