Results 81 to 90 of about 971 (184)
Two new bisindole alkaloids, biscarpamontamine A (1), possessing an aspidosperma−iboga-type skeleton, and biscarpamontamine B (2), having an aspidosperma−aspidosperma-type skeleton, were isolated from stems of Tabernaemontana sphaerocarpa, and their ...
Motoo Shiro (1670407) +9 more
core +2 more sources
Circular dichroism studies of bisindole Vinca alkaloids
Abstract The analysis of a series of seventeen vinblastine analogs by circular dichroism is described. Exciton coupling of the indole and indoline chromophores of these compounds provides a general, non-empirical method for the assignment of the C16′ configuration with the bioactive C16′-S and the inactive C16′-R analogs giving rise, respectively, to
Craig A. Parish +5 more
openaire +1 more source
Cyphostemma adenocaule is a therapeutic plant traditionally used to treat rabies, snake bite, diarrhea, and wound healing. To address the bioactive compounds exhibiting these activities, we performed a comprehensive study on the roots of the plant.
Hadush Gebrehiwot +8 more
wiley +1 more source
A reinvestigation of the roots of Strychnos icaja resulted in the isolation of a new bisindole alkaloid named strychnobaillonine (1) with original C-17–N-1′ and C-23–C-17′ junctions, in addition to sungucine, bisnordihydrotoxiferine, and strychnohexamine
Georges Dive (1816540) +6 more
core +1 more source
Ajmaline, Oxindole, and Cytotoxic Macroline–Akuammiline Bisindole Alkaloids from Alstonia penangiana
Examination of the EtOH extract of the Malayan Alstonia penangiana resulted in the isolation of 10 new alkaloids, comprising two ajmaline (1, 2), four macroline oxindole (3–6), and four macroline–akuammiline bisindole alkaloids (7–10).
Suerialoasan Navanesan (785142) +7 more
core +3 more sources
Synthesis of the indenotryptoline bisindole alkaloid, BE-54017, was accomplished using osmium-promoted cis-dihydroxylation of maleimide as a key step. After optical resolution, the absolute configuration of this molecule was determined by comparing its ...
Tomoyuki Kimura (1896370) +5 more
core +1 more source
Macroline–Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana
A methanol extract of the stem bark of the Malayan Alstonia penangiana provided seven new bisindole alkaloids, comprising six macroline-sarpagine alkaloids (angustilongines E-K, 1-6) and one macroline-pleiocarpamine bisindole alkaloid (angustilongine L ...
Low, Yun Yee +6 more
core +1 more source
Cytotoxic Bisindole Alkaloids from a Marine Sponge Spongosorites sp.
Three new bisindole alkaloids of the hamacanthin class (1−3) and one new bisindole alkaloid of the topsentin class (6) were isolated along with known bisindole alkaloids (4, 5, 7−11) from the MeOH extract of a marine sponge Spongosorites sp.
Qishi Sun (2681866) +7 more
core +1 more source
Synthesis of Topsentin‐A, A Bisindole Alkaloid of the Marine Sponge Topsentia genitrix
AbstractThe synthesis of topsentin‐A, a bisindole alkaloid isolated from the maring sponge Topsentia genitrix, has been achieved starting from 3‐acetylindole.
Braekman, Jean Claude +2 more
openaire +3 more sources
Angustifonines A and B, Cytotoxic Bisindole Alkaloids from Bousigonia angustifolia
Two new bisindole alkaloids, angustifonines A (1) and B (2), comprising the union of a rearranged monoterpenoid quinoline and an aspidospermine alkaloid, as well as 27 known indole alkaloids were isolated from the twigs and leaves of Bousigonia ...
Yu Zhang (12946) +5 more
core +1 more source

