Results 91 to 100 of about 971 (184)

Effect and Structure-Activity Relationship Between Isatin and its Dimer Indirubin on Neural Development of Transgenic Zebrafish

Natural Product Communications
Objective Isatin (2,3-indolinedione, ISA), as an indole oxide, is widely distributed in mammalian tissues and fluids, with concentrations varying from less than 0.1 to greater than 10 μM. Indirubin (2-(2-oxo-1h-indol-3-ylidene)-1h-indol-3-one, IND), as a
Yonghua Liu, Ke Zhou, Peida Feng, Chenli Xu, Jiayu Zhou, Chengniu Wang, Xiaofang Tan, Ying Chen   +7 more
doaj   +1 more source

Macroline–Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana

, 2019
A methanol extract of the stem bark of the Malayan Alstonia penangiana provided seven new bisindole alkaloids, comprising six macroline–sarpagine alkaloids (angustilongines E–K, 1–6) and one macroline–pleiocarpamine bisindole alkaloid (angustilongine L ...
Yun-Yee Low, Toh-Seok Kam, Joanne Soon-Yee Yeap (5205269), Kae-Shin Sim, Chun-Hoe Tan, Siew-Huah Lim (1426534), Hazwani Mat Saad (7533452), Hazwani Mat Saad, Siew-Huah Lim, Joanne Soon-Yee Yeap, Yun-Yee Low (1426531), Chun-Hoe Tan (7533455), Kae-Shin Sim (666138), Toh-Seok Kam (1426537)   +13 more
core   +1 more source

Ajmaline, Oxindole, and Cytotoxic Macroline–Akuammiline Bisindole Alkaloids from Alstonia penangiana

, 2018
Examination of the EtOH extract of the Malayan Alstonia penangiana resulted in the isolation of 10 new alkaloids, comprising two ajmaline (1, 2), four macroline oxindole (3-6), and four macroline-akuammiline bisindole alkaloids (7-10).
Yong, Kien Thai, Yun-Yee Low, Toh-Seok Kam, Low, Yun Yee, Lim, Siew Huah, Suerialoasan Navanesan, Kae-Shin Sim, Sim, Kae Shin, Yeap, Joanne Soon Yee, Kien-Thai Yong, Subramaniam Gurusamy, Navanesan, Suerialoasan, Siew-Huah Lim, Kam, Toh Seok, Joanne Soon-Yee Yeap, Gurusamy, Subramaniam   +15 more
core   +1 more source

Cytotoxic Vobasine, Tacaman, and Corynanthe-Tryptamine Bisindole Alkaloids from Tabernaemontana and Structure Revision of Tronoharine

, 2016
Seven new indole alkaloids (1–7) comprising four vobasine, two tacaman, and one corynanthe-tryptamine bisindole alkaloid were isolated from the stem-bark extract of a Malayan Tabernaemontana.
Kam-Weng Chong (1715197), Yun-Yee Low (1426531), Dawn Su-Yin Sim (1715200), Kae-Shin Sim (666138), Toh-Seok Kam (1426537), Choy-Eng Nge (1701916)   +5 more
core   +1 more source

Qualitative and quantitative evaluation of bisindole usambarane alkaloids in Strychnos usambarensis roots by high performance liquid chromatography diode-array

, 1998
peer reviewedA high performance liquid chromatographic method for the simultaneous determination of bisindole usambarane alkaloids from the roots of Strychnos usambarensis using a diode-array detector is proposed, The system, consisting of a RP-8 Select ...
Angenot, Luc, Frederich, Michel, Cunha, M.A., van den Berg, K.J., Tits, Monique, Pereira, H., Bento, M.F., Boon, J.J., Moutinho, A.M.C.   +8 more
core   +1 more source

Conolodinines A–D, Aspidosperma–Aspidosperma Bisindole Alkaloids with Antiproliferative Activity from Tabernaemontana corymbosa

, 2019
Examination of the EtOH extract of the leaves of the Malayan Tabernaemontana corymbosa resulted in the isolation of four new (1-4) and two known bisindole alkaloids (5, 6) of the Aspidosperma-Aspidosperma type.
Sim, Dawn Su Yin, Navanesan, Suerialoasan, Low, Yun Yee, Lim, Siew Huah, Kam, Toh Seok, Gurusamy, Subramaniam, Sim, Kae Shin   +6 more
core   +1 more source

Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling. [PDF]

Oncotarget, 2017
Jie C, Luo Z, Chen H, Wang M, Yan C, Mao ZF, Xiao GK, Kurihara H, Li YF, He RR.   +9 more
europepmc   +1 more source

12'-hydroxyisostrychnobiline, a new alkaloid from Strychnos variabilis [PDF]

, 1979
peer reviewedThe structure of a new bisindole alkaloid, 12'-hydroxyisostrychnobiline, has been proposed from the analysis of its 300 MHz H NMR spectrum and comparison of the spectroscopic data with those of various monomeric and dimeric alkaloids ...
Angenot, Luc, Tavernier, Dirk, Tits, Monique   +2 more
core  

16,17-didehydroisostrychnobiline, new asymmetrical bisdindole alkaloid from Strychnos variabilis [PDF]

, 1983
peer reviewedWe describe a new asymmetrical bisindole alkaloid, 16,17-didehydroisostrychnobiline, that was isolated by reverse phase liquid chromatography from the root barks of Strychnos variabilis.
Angenot, Luc, Tavernier, Dirk, Tits, Monique   +2 more
core  

Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling. [PDF]

Oncotarget, 2016
Kong LM, Feng T, Wang YY, Li XY, Ye ZN, An T, Qing C, Luo XD, Li Y.   +8 more
europepmc   +1 more source