Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Indole Alkaloids Isolated from Catharanthus roseus (L.) G. Don Cultivated Conventionally and Derived from In vitro Cultures [PDF]
, 2016 Catharanthus roseus (periwinkle) is a medicinal plant commonly known for its wide biological activity. In many countries different parts of this plant are used for the treatment of diabetes, hypertension and for menstrual regulation.
GRZESZCZUK, Monika +3 more
core +2 more sources
Stereoselective Synthesis of 2-(2-Aminoalkyl)- and 1,3-Disubstituted Tetrahydro-1H-pyrido[4,3-b]- Benzofuran and Indole Derivatives [PDF]
, 2016 The addition of an allenyl indium intermediate to chiral N-tert-butanesulfinyl imines 7 proceeds with high levels of diastereocontrol. The resulting homopropargylic amine derivatives 10 were transformed into 2-(2-aminoalkyl)benzofuran and indole ...
Foubelo, Francisco +2 more
core +3 more sources
Exploring the production of high-value compounds in plant Catharanthus roseus hairy roots and yeast Yarrowia lipolytica [PDF]
, 2017 This dissertation focuses on studying the production of two categories of high-value compounds in bio organisms. The first group is terpenoid indole alkaloids (TIAs) in plant Catharanthus roseus, and the second group is wax esters, one of fatty acid ...
Zhao, Le
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Natural Product CommunicationsObjective Isatin (2,3-indolinedione, ISA), as an indole oxide, is widely distributed in mammalian tissues and fluids, with concentrations varying from less than 0.1 to greater than 10 μM. Indirubin (2-(2-oxo-1h-indol-3-ylidene)-1h-indol-3-one, IND), as a
Yonghua Liu +7 more
doaj +1 more source
The Chemistry of Grandifoline, a Bisindole Alkaloid
, 1979 Department of Pure Chemistry, University College of Science, 92, Acharya P. C.
openaire +1 more source
MOLECULAR DOCKING OF HYRTIMOMINE A-K FROM MARINE SPONGE HYRTIOS SPP. AS ANTICANCER TARGET OF PHOSPHOINOSITIDE-DEPENDENT KINASE 1 [PDF]
, 2019 Objective: The hyrtimomine A-K class of indole-based compounds extracted from Hyrtios spp. of sponges from the sea has not been studied for their anticancer properties.
RAMA ADIGA
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Synthesis of 3,6-Bis(5’-bromo-3’-indolyl)-1,4-dimethypiperazine-2,5-dione [PDF]
, 2009 The one-pot synthesis of 3,6-bis(5’-bromo-3’-indolyl)-1,4-dimethylpiperazine- 2,5-dione is reported. Sarcosine anhydride is brominated and immediately reacted with 5-bromoindole to produce the product, which is characterized by 1H NMR, MS and ...
Crooke, Stephen N. +2 more
core +1 more source
Development and Praxis of Ph Drug Delivery System Contra Zika
, 2023 As the effects of global warming continue to spread throughout the world, another critical issue is slowly gaining attention in many urban tropical countries.
Rodriguez, Julissa
core +1 more source
Radical mediated heterocycle functionalization: methodology development and natural product synthesis [PDF]
, 2015 Substituted heterocycles are common building-blocks for biologically relevant molecules and represent challenging synthetic targets. Due to limited methods available for their preparation and derivatization, direct C-H functionalization protocols offer ...
Furst, Laura
core +1 more source
Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling. [PDF]
Oncotarget, 2017 Jie C +9 more
europepmc +1 more source