Results 71 to 80 of about 971 (184)
Food Science &Nutrition, Volume 12, Issue 12, Page 9951-9973, December 2024.This study discussed the therapeutic capacity of various polyphenols, terpenoids, and alkaloids on CRC via the PI3K/Akt/mTOR pathway. Each bioactive component causes various physiological processes, such as triggering free radical production, disruption of mitochondrial membrane potential, cell cycle arrest, inhibition of CRC stem cell migration ...
Kübra Demir +4 more
wiley +1 more source
, 2018 Four new monoterpenoid bisindole alkaloids, flabellipparicine (1), 19,20-dihydrovobparicine (2), 10′-demethoxy-19,20-dihydrovobatensine D (3), and 3′-(2-oxopropyl)ervahanine A (4), and 10 known monoterpenoid indole alkaloids were isolated from the stems
Ze-Hong Miao (1688248) +21 more
core +1 more source
Mechanochemistry in Organic Synthesis: An Italian Journey through Innovations
European Journal of Organic Chemistry, Volume 27, Issue 30, August 12, 2024.The contribution of Italy to the development of mechanochemistry dates back to 1988 with the first studies on metal alloys. With the progress of time, it has flourished not only in the field of organic chemistry, but also in other scientific fields due to the enormous interest of Italian researchers in the various advantages brought by this technique ...
Francesco Basoccu +2 more
wiley +1 more source
Molecular Networking‐Guided Discovery of Kyonggic Acids in Massilia spp.
European Journal of Organic Chemistry, Volume 27, Issue 17, May 3, 2024.The metabolomes of six Massilia strains were analyzed using a molecular‐networking guided approach, revealing interconnections among metabolites. A closer inspection of the most promising strains led to the discovery of novel N‐acylated amino acids, termed kyonggic acids.
Till Steinmetz +3 more
wiley +1 more source
The Plant Genome, Volume 17, Issue 1, March 2024.Abstract Terpenoids are the main active components in the Zanthoxylum armatum leaves, which have extensive medicinal value. The Z. armatum leaf is the main by‐product in the Z. armatum industry. However, the transcription factors involved in the biosynthesis of terpenoids are rarely reported.
Xiaomeng Liu +9 more
wiley +1 more source
BiomoleculesCandidiasis is considered an emerging public health concern because of the occurrence of drug-resistant Candida strains and the lack of an available structurally diverse antifungal drug armamentarium.
Joe Anthony H. Manzano +4 more
doaj +1 more source
Synthesis of Alkaloids and Compounds Containing the 3,4‐Benzomorphan Scaffold
European Journal of Organic Chemistry, Volume 27, Issue 1, January 2, 2024.This review summarizes the biosynthesis and the synthesis of several biologically active natural compounds (i. e., alkaloids) and other related compounds containing the hexahydro‐2,6‐methano‐1‐benzazocine structure (i. e., 3,4‐benzomorphan scaffold). Abstract Several natural products, bearing an embedded hexahydro‐2,6‐methano‐1‐benzazocine framework (3,
Laura G. Rodríguez +2 more
wiley +1 more source
The Raputindoles: Novel Cyclopentyl Bisindole Alkaloids from Raputia simulans
Organic Letters, 2010 A novel class of bisindole alkaloids is established by the isolation and structural determination of raputindoles A-D (1-4) from the Amazonian plant Raputia simulans Kallunki (Rutaceae). Complete spectroscopic characterization was accomplished by means of NMR spectroscopy and APCI (+) HRMS.
Vougogiannopoulou, K. +4 more
openaire +3 more sources
Journal of Cellular and Molecular Medicine, Volume 28, Issue 1, January 2024.Abstract Breast cancer is the most prevalent cancer worldwide and its incidence increases with age, posing a significant threat to women's health globally. Due to the clinical heterogeneity of breast cancer, the majority of patients develop drug resistance and metastasis following treatment.
Anqi Ge +11 more
wiley +1 more source
, 2018 peer reviewedStrychnogucine B is a bisindole alkaloid previously isolated from Strychnos icaja that possesses promising in vitro antiplasmodial properties. This compound was synthesized in four steps from (−)-strychnine. As no acute toxicity was observed
Teijaro, Christiana +14 more
core +1 more source