Results 71 to 80 of about 48,569 (170)

Bisnicalaterine A, a Vobasine−Vobasine Bisindole Alkaloid from Hunteria zeylanica

, 2016
A new bisindole alkaloid, bisnicalaterine A (1), consisting of two vobasine-type skeletons, and 3-epivobasinol (2) and 3-O-methylepivobasinol (3), with vobasine-type skeletons, were isolated from the leaves of Hunteria zeylanica, and their structures ...
A. Hamid A. Hadi (112781), Hiroshi Morita (124362), Yusuke Hirasawa (1562092), Yukihiro Goda (1661827), Alfarius E. Nugroho (2196652), Khalijah Awang (236138), Nobuo Kawahara (1647856)   +6 more
core   +1 more source

Synthesis of Alkaloids and Compounds Containing the 3,4‐Benzomorphan Scaffold

European Journal of Organic Chemistry, Volume 27, Issue 1, January 2, 2024.
This review summarizes the biosynthesis and the synthesis of several biologically active natural compounds (i. e., alkaloids) and other related compounds containing the hexahydro‐2,6‐methano‐1‐benzazocine structure (i. e., 3,4‐benzomorphan scaffold). Abstract Several natural products, bearing an embedded hexahydro‐2,6‐methano‐1‐benzazocine framework (3,
Laura G. Rodríguez, Josep Bonjoch, Ben Bradshaw   +2 more
wiley   +1 more source

Mechanism of ferroptosis in breast cancer and research progress of natural compounds regulating ferroptosis

Journal of Cellular and Molecular Medicine, Volume 28, Issue 1, January 2024.
Abstract Breast cancer is the most prevalent cancer worldwide and its incidence increases with age, posing a significant threat to women's health globally. Due to the clinical heterogeneity of breast cancer, the majority of patients develop drug resistance and metastasis following treatment.
Anqi Ge, Qi He, Da Zhao, Yuwei Li, Junpeng Chen, Ying Deng, Wang Xiang, Hongqiao Fan, Shiting Wu, Yan Li, Lifang Liu, Yue Wang   +11 more
wiley   +1 more source

A New Indole Alkaloid from Voacanga grandifolia [PDF]

, 2014
A new bisindole alkaloid, voacalgine F (1), has been isolated from the bark of Indonesian Voacanga grandifollia (Miq.) Rolfe.
Osamu Shirota, -, Yusuke Hirasawa, -, Alfarius Eko Nugroho, -, Toshio Kaneda, -, Abdul Rahman, -, Idha Kusumawati, -, Azusa Haseo, -, Noor Cholies Zaini, -, Hiroshi Morita, -   +8 more
core   +1 more source

Antibacterial and Antioxidant Efficacies of Secondary Metabolites from the Roots of Cyphostemma adenocaule: A Combined In Vitro and In Silico Study

Journal of Tropical Medicine, Volume 2024, Issue 1, 2024.
Cyphostemma adenocaule is a therapeutic plant traditionally used to treat rabies, snake bite, diarrhea, and wound healing. To address the bioactive compounds exhibiting these activities, we performed a comprehensive study on the roots of the plant.
Hadush Gebrehiwot, Yadessa Melaku, Muhdin Aliye, Urgessa Ensermu, Aman Dekebo, Milkyas Endale, Daniel Rentsch, Mo Hunsen, Zhengwei Huang   +8 more
wiley   +1 more source

Flabellipparicine, a Flabelliformide-Apparicine-Type Bisindole Alkaloid from Tabernaemontana divaricata

, 2018
Four new monoterpenoid bisindole alkaloids, flabellipparicine (1), 19,20-dihydrovobparicine (2), 10′-demethoxy-19,20-dihydrovobatensine D (3), and 3′-(2-oxopropyl)­ervahanine A (4), and 10 known monoterpenoid indole alkaloids were isolated from the stems
Ze-Hong Miao (1688248), Guofu Qiu (1664314), Congkui Tian, Rong Huang (298496), Sheng-Ping Yang, Shugeng Cao, Guofu Qiu, Attila Mándi, Attila Mándi (1476106), You-Sheng Cai (2221918), Ting-Lan Zhou (5706938), You-Sheng Cai, Ting-Lan Zhou, Ze-Hong Miao, Tibor Kurtán, Ariel M. Sarotti (1366479), Congkui Tian (5706941), Shugeng Cao (116898), Tibor Kurtán (1476103), Sheng-Ping Yang (1612948), Ariel M. Sarotti, Rong Huang   +21 more
core   +1 more source

Circular dichroism studies of bisindole Vinca alkaloids

Tetrahedron, 1998
Abstract The analysis of a series of seventeen vinblastine analogs by circular dichroism is described. Exciton coupling of the indole and indoline chromophores of these compounds provides a general, non-empirical method for the assignment of the C16′ configuration with the bioactive C16′-S and the inactive C16′-R analogs giving rise, respectively, to
Craig A. Parish, Jian-Guo Dong, William G. Bornmann, Joan Chang, Koji Nakanishi, Nina Berova   +5 more
openaire   +1 more source

Macroline–Sarpagine Bisindole Alkaloids with Antiproliferative Activity from Alstonia penangiana

, 2019
A methanol extract of the stem bark of the Malayan Alstonia penangiana provided seven new bisindole alkaloids, comprising six macroline-sarpagine alkaloids (angustilongines E-K, 1-6) and one macroline-pleiocarpamine bisindole alkaloid (angustilongine L ...
Low, Yun Yee, Lim, Siew Huah, Kam, Toh Seok, Tan, Chun Hoe, Sim, Kae Shin, Yeap, Joanne Soon Yee, Saad, Hazwani Mat   +6 more
core   +2 more sources

In vivo antimalarial and antitrypanosomal activity of strychnogucine B, a bisindole alkaloid from Strychnos icaja.

, 2018
peer reviewedStrychnogucine B is a bisindole alkaloid previously isolated from Strychnos icaja that possesses promising in vitro antiplasmodial properties. This compound was synthesized in four steps from (−)-strychnine. As no acute toxicity was observed
Teijaro, Christiana, Teijaro, CN, Quetin-Leclercq, Joëlle, Andrade, Rodrigo B, Andrade, RB, Beaufays, Claire, Teijaro, Christiana N, Zhao, S, Zhao, Senzhi, Frederich, Michel, bordignon, Annélise, Ledoux, Allison, Andrade, Rodrigo, Jansen, Olivia, Beaufay, Claire   +14 more
core   +1 more source

Conofolidine: A Natural Plant Alkaloid That Causes Apoptosis and Senescence in Cancer Cells

Molecules
Natural products contribute substantially to anticancer therapy; the plant kingdom provides an important source of molecules. Conofolidine is a novel Aspidosperma-Aspidosperma bisindole alkaloid isolated from the Malayan plant Tabernaemontana corymbosa ...
Mohammed Zuhair Al-Hayali, Choy-Eng Nge, Kuan Hon Lim, Hilary M. Collins, Toh-Seok Kam, Tracey D. Bradshaw   +5 more
doaj   +1 more source