Results 51 to 60 of about 48,569 (170)

Flabellipparicine, a Flabelliformide-Apparicine-Type Bisindole Alkaloid from Tabernaemontana divaricata [PDF]

open access: yes, 2018
Four new monoterpenoid bisindole alkaloids, flabellipparicine (1), 19,20-dihydrovobparicine (2), 10′-demethoxy-19,20-dihydrovobatensine D (3), and 3′-(2-oxopropyl)ervahanine A (4), and 10 known monoterpenoid indole alkaloids were isolated from the stems ...
Mándi, Attila   +10 more
core   +1 more source

1H NMR Spectroscopy and MVA Analysis of Diplodus sargus Eating the Exotic Pest Caulerpa cylindracea

open access: yesMarine Drugs, 2015
The green alga Caulerpa cylindracea is a non-autochthonous and invasive species that is severely affecting the native communities in the Mediterranean Sea. Recent researches show that the native edible fish Diplodus sargus actively feeds on this alga and
Sandra A. De Pascali   +5 more
doaj   +1 more source

Ligand‐Based Pharmacophore Mapping and Virtual Screening for the Search of Biguanide‐Like Molecules With Antidiabetic Potentials Targeting Liver Kinase B1

open access: yesBiochemistry Research International, Volume 2026, Issue 1, 2026.
Type 2 diabetes mellitus (T2DM) is a state where the body’s glucose metabolism is compromised. AMP‐activated protein kinase, or AMPK, has an important part to play in glucose metabolism, and the liver kinase B1 (LKB1) protein functions as a major upstream kinase for AMPK activation, thereby making it appealing therapeutic targets for treating and ...
Rumman Reza   +6 more
wiley   +1 more source

Studies of New Indole Alkaloid Coupling Methods for the Synthesis of Haplophytine

open access: yes, 2016
The two novel bisindole alkaloid structures shown can be synthesized in a few steps from the canthiphytine derivative ...
Yuan Tian (225002)   +2 more
core   +5 more sources

Aspidosperma pyrifolium, a medicinal plant from the Brazilian caatinga, displays a high antiplasmodial activity and low cytotoxicity

open access: yesMalaria Journal, 2018
Background Several species of Aspidosperma plants are referred to as remedies for the treatment of malaria, especially Aspidosperma nitidum. Aspidosperma pyrifolium, also a medicinal plant, is used as a natural anti-inflammatory.
Isabela P. Ceravolo   +5 more
doaj   +1 more source

Arenaria serpyllifolia as a Natural Antiviolaceum Agent: Phytochemical, Biological, and Molecular Approaches

open access: yesChemistryOpen, Volume 14, Issue 11, November 2025.
Arenaria serpyllifolia extract exhibits strong antioxidant, antimicrobial, antibiofilm, and antiquorum sensing activities. Key compounds, including levoglucosan and guanosine, show potent CviR receptor binding. Violacein inhibition and molecular dynamics confirm their stability, highlighting their potential as quorum sensing inhibitors and therapeutic ...
Meryem Burcu Külahcı   +5 more
wiley   +1 more source

Huncaniterine A, a New Bisindole Alkaloid from Hunteria zeylanica

open access: yes, 2007
A new bisindole alkaloid, huncaniterine A (1) consisting of corynantheine-type and aspidospermane-type skeletons, has been isolated from the bark of Hunteria zeylanica (Apocynaceae) and the structure was elucidated on the basis of spectroscopic data ...
Hirasawa, Yusuke   +9 more
core   +1 more source

Chapter 3 Noniridoid Bisindole Alkaloids

open access: yes, 1995
This chapter discusses that indole is a reactive nucleus prone to dimerization when it is isolated or a part of tryptamine or tryptophan, which themselves are reactive toward many functionalities. For these reasons, bisindoles, the majority of which are of iridoid origin, are frequently isolated in nature. Besides these “dimers,” there exists a growing
Sapi, J., Massiot, G.
openaire   +1 more source

Bisleucocurine A, a novel bisindole alkaloid from Leuconotis griffithii

open access: yes, 2010
A novel bisindole alkaloid, bisleucocurine A (1), consisting of two strychnan skeletons with an N-1-C-17\u27 and a C-12-C-2\u27 bridges, was isolated from the leaves of Leuconotis griffithii and the structure was elucidated on the basis of spectroscopic ...
Hirasawa, Y.   +5 more
core   +1 more source

Bipleiophylline, an Unprecedented Cytotoxic Bisindole Alkaloid Constituted from the Bridging of Two Indole Moieties by an Aromatic Spacer Unit

open access: yes, 2016
A cytotoxic bisindole alkaloid possessing an unprecedented structure in which two indole moieties are bridged by an aromatic spacer unit has been isolated from Alstonia angustifolia. The structure was established by analysis of the spectroscopic data and
Seik-Weng Ng (1472446)   +3 more
core   +2 more sources

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